Content area
Abstract
Narcolepsy is a sleep disorder caused by selective loss of orexin-producing neurons. Scammell and colleagues describe the functions of orexin neurons and the effects of their loss and review evidence implicating the immune system in the pathogenesis of the disorder.
Details
Title
The neurobiological basis of narcolepsy
Author
Mahoney, Carrie E 1
; Cogswell, Andrew 2 ; Koralnik, Igor J 2 ; Scammell, Thomas E 1
1 Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
2 Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA
; Cogswell, Andrew 2 ; Koralnik, Igor J 2 ; Scammell, Thomas E 1 1 Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
2 Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA
Pages
83-93
Publication year
2019
Publication date
Feb 2019
ISSN
1471003X
e-ISSN
14693178
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2169822942
Copyright
Copyright Nature Publishing Group Feb 2019