Central unilocular mucoepidermoid carcinoma of the mandible: A case report and literature review

Abstract

[1,2] This malignant tumor composed a mixture of the epithelial, mucin-producing, and intermediate cells. this malignancy may occur in all ages, but its prevalence increases in the fourth and fifth decades of life. Various possible origins have been considered, as follows: a. Entrapment of the retromolar mucous glands within the mandibular jaw, which shows neoplastic transformation thereafter b. Embryonic remnants of the submandibular and sublingual glands trapped within the mandible during development c. Neoplastic transformation and invasion from the lining of the maxillary sinus d. Neoplastic transformation of the mucous-secreting cells from the epithelial lining of the dentigerous cyst associated with impacted third molars e. Neoplastic transformation of entrapped minor salivary glands within the maxilla. CASE REPORT A 47-year-old woman referred to the Department of Oral and Maxillofacial Surgery at Dental School of Isfahan University of Medical Sciences, exhibiting a lesion in the right posterior region of the mandible, which had been present for the previous 4 months. High grade was characterized by larger bone destruction, enlarged frequency of relapses, and presence of regional and distant metastases.1[16] CONCLUSION CMEC is rare in the jaws; however, since the lesion's behavior is different clinically and radiographically, it is important that the clinician should be aware of the various presentations of a particular disease process and try to achieve the diagnosis accurate and fast.