Content area
Abstract
Although opioids are recommended and frequently used in the acute phase of ST-elevation myocardial infarction (STEMI), their use is accompanied by serious side effects. In particular, gastrointestinal adverse effects may disturb absorption of essential oral medication like platelet inhibitors. This may cause suboptimal platelet inhibition and increased risk of acute stent thrombosis. Some clinical studies have already demonstrated these negative results. Alternative strategies to optimize platelet inhibition and pain relief in STEMI are being investigated. Clinicians should become more aware of the potential side effects of opioids in STEMI.
Details
Title
Risks of Opioids in ST-Elevation Myocardial Infarction: A Review
Author
Tavenier, Anne Henrieke 1 ; Hermanides, Renicus Suffridus 1 ; Ottervanger, Jan Paul 1 ; Ter Horst, Peter Gerrit Johannes 2 ; Kedhi, Elvin 1 ; van't Hof, Adriaan W J
1 Department of Cardiology, Isala, Dr. van Heesweg 2, 8025 AB Zwolle, The Netherlands
2 Department of Clinical Pharmacy, Isala, Zwolle, The Netherlands
1 Department of Cardiology, Isala, Dr. van Heesweg 2, 8025 AB Zwolle, The Netherlands
2 Department of Clinical Pharmacy, Isala, Zwolle, The Netherlands
Pages
1303-1308
Section
REVIEW ARTICLE
Publication year
2018
Publication date
Dec 2018
ISSN
01145916
e-ISSN
11791942
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2190333078
Copyright
Copyright Springer Nature B.V. Dec 2018