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ABSTRACT
Nowadays, with the rapid developments in nanotechnology, there has been a significant increase in the usage of nanoparticles within the biomedical field. Nanoparticles are known as particles ranging in size between 1 and 100 nm. Especially, silver nanoparticles (AgNPs) have been extensively carried out biomedical areas because of their physicochemical, and biological therapeutic properties. Recent studies have shown that there are anti-fungal, anti-viral, anti-inflammatory, anti-angiogenic biological activities, especially anti-bacterial and anti-cancer features of silver nanoparticles. Also, the appropriate knowledge of these characteristics is crucial since this knowledge enhances their potential usage in many areas while decreasing their possible dangers for human and environment. Recent researches demonstrate that multifunctional cytotoxic biological activities of biosynthesized silver nanoparticles can be used as an anti-cancer agent. In this work, it is aimed to give a literature review of the studies on silver nanoparticles, synthesis techniques and their possible usages especially in cancer therapy.
Key Words: Silver nanoparticles, Anticancer, Nanotechnology
Introduction
Nanotechnology, developing area, has several interdisciplinary fields, like electronics, medicine and biomaterials. Nanomedicine, in the long run aims to improve the health care system by dealing with mortal diseases more efficiently. Nanotechnology, ranging in size from 10 nm to 1000 nm, involves the design, synthesis and manipulation of structures in particles.
For creation of nanoscale value properties, microbial origins and plants are used because of their physical and chemical properties. Currently, nanobiotechnology is seen as means of producing the synthesis of nanoparticles an economical option for chemical and physical methods (1,2). Nanoparticles have unique chemical, physical and biological properties, and they are used in a lot of fields like therapeutics, cosmetics and drug delivery (3).
Nanoparticles present a new perspective for detection, protection and treatment of tumors. Because of, the speed improvement of varied diagnostic devices and therapeutic strategies, the mortality of cancer, known as one of the most deadly disease, has been significantly inhibited. Unfortunately, there is no method to select and bind cancer cells in order to prevent toxicity and side effects in all current cancer treatments. To overcome this situation, the synthesis of nanoparticles emerges as a new additive. To over come this problem, nanoparticles synthesis are emerged as a new contribution (4). Also, nanoparticles have been currently widely used in biomedical area due...