Content area
Abstract
A 35-year-old man is brought to the emergency department after ingesting automobile antifreeze. His pH is 7.30, and his urinalysis reveals calcium oxalate crystals, findings consistent with ethylene glycol poisoning. Treatment with fomepizole is recommended. Fomepizole is a competitive inhibitor of alcohol dehydrogenase that prevents the formation of the toxic metabolites of ethylene glycol and methanol.
Details
Title
Fomepizole for Ethylene Glycol and Methanol Poisoning
Author
Brent, Jeffrey, MD, PhD
Pages
2216-23
Section
50; 52; Clinical Therapeutics
Publication year
2009
Publication date
May 21, 2009
Website
ISSN
00284793
e-ISSN
15334406
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
223909406
Copyright
Copyright © 2009 Massachusetts Medical Society. All rights reserved.