Brief Report: Severe Symptoms of

Abstract

A patient who appeared to have typical acute promyelocytic leukemia, both morphologically and cytogenetically, in whom tretinoin induced a marked increase in basophils and hyperhistaminemia resulting in shock and severe gastric and duodenal ulceration, is discussed.

Details

Title

Brief Report: Severe Symptoms of Hyperhistaminemia After the Treatment of Acute Promyelocytic Leukemia with Tretinoin (All-Trans-Retinoic Acid)

Author

Koike, Tadashi, MD; Tatewaki, Wataru, MD; Aoki, Azusa, MD; Yoshimoto, Haruko, MD; Yagisawa, Kumiko; Hashimoto, Shigeo, MD; Furukawa, Tatsuo, MD; Saitoh, Hiroyuki, MD; Takahashi, Masuhiro, MD; Li-bo, Yang, MD; Ying, Wang, MD; Shibata, Akira, MD

Pages

385-387

Section

Original Article

Publication year

1992

Publication date

Aug 6, 1992

Publisher

Massachusetts Medical Society

Website

http://www.nejm.org

ISSN

00284793

e-ISSN

15334406

Source type

Scholarly Journal

Language of publication

English

ProQuest document ID

223946978

Brief Report: Severe Symptoms of Hyperhistaminemia After the Treatment of Acute Promyelocytic Leukemia with Tretinoin (All-Trans-Retinoic Acid)

Content area

Abstract

Details

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