Details
Title
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
Author
Park, Tae-Eun 1
; Mustafaoglu, Nur 2 ; Herland, Anna 3 ; Hasselkus, Ryan 2
; Mannix, Robert 4 ; FitzGerald, Edward A 2
; Prantil-Baun, Rachelle 2 ; Watters, Alexander 2 ; Henry, Olivier 2 ; Benz, Maximilian 2
; Sanchez, Henry 2 ; McCrea, Heather J 5 ; Goumnerova, Liliana Christova 5
; Song, Hannah W 6 ; Palecek, Sean P 6 ; Shusta, Eric 6 ; Ingber, Donald E 7
1 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea
2 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA
3 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Division of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden; Swedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
4 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Vascular Biology Program and Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA
5 Department of Neurosurgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA
6 Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI, USA
7 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA; Vascular Biology Program and Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA
; Mustafaoglu, Nur 2 ; Herland, Anna 3 ; Hasselkus, Ryan 2
; Mannix, Robert 4 ; FitzGerald, Edward A 2
; Prantil-Baun, Rachelle 2 ; Watters, Alexander 2 ; Henry, Olivier 2 ; Benz, Maximilian 2
; Sanchez, Henry 2 ; McCrea, Heather J 5 ; Goumnerova, Liliana Christova 5
; Song, Hannah W 6 ; Palecek, Sean P 6 ; Shusta, Eric 6 ; Ingber, Donald E 7
1 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea
2 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA
3 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Division of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden; Swedish Medical Nanoscience Center, Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
4 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Vascular Biology Program and Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA
5 Department of Neurosurgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA
6 Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI, USA
7 Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA; Vascular Biology Program and Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA
Pages
1-12
Publication year
2019
Publication date
Jun 2019
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2239631445
Copyright
© 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.