Abstract
While genomics links gene activity with disease, proteomics investigates gene expression i.e. the proteins which are the ultimate effector molecules; and hence more relevant to identification of biomarkers. The basic steps of proteomics include (i) albumin removal; (ii) proteins digestion; (iii) protein separation step; and (iv) analysis by mass spectrometry [2],[5],[6],[7]. The methods commonly used currently for proteomic analysis are [6] : (i) two-dimensional gel electrophoresis followed by mass spectrometry (2DE-MS); (ii) liquid chromatography followed by mass spectrometry (LC-MS).
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details
1 Department of Nephrology, All India Institute of Medical Sciences, New Delhi 110 029