Content area
Abstract
Catalytic asymmetric transfer hydrogenation of aromatic alkyl ketones has been investigated using [Ru(p-cymene)Cl2]2 and new derivatives of β-amino alcohols synthesized from (S)-(−)-lactic acid and mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60–90%) and moderate to good enantioselectivities (40–86%).
Graphical Abstract
Asymmetric transfer hydrogenation of ketones has been investigated using [Ru(p-cymene)Cl2]2 and β-amino alcohols synthesized from (S)-(−)-lactic acid and Mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60–90%) and moderate to good enantioselectivities (40–86%).
Details
Title
Catalytic Asymmetric Transfer Hydrogenation of Ketones Using [Ru(p-cymene)Cl2]2 with Chiral Amino Alcohol Ligands
Author
Deshpande, Sudhindra H 1 ; Kelkar, Ashutosh A 1 ; Gonnade, Rajesh G 2 ; Shingote, Savita K 1 ; Chaudhari, Raghunath V 3
1 Chemical Engineering and Process Development Division, National Chemical Laboratory, Pune, India
2 Center for Materials Characterization, National Chemical Laboratory, Pune, India
3 Department of Chemical and Petroleum Engineering, Center for Environmentally Beneficial Catalysis, The University of Kansas, Lawrence, KS, USA
1 Chemical Engineering and Process Development Division, National Chemical Laboratory, Pune, India
2 Center for Materials Characterization, National Chemical Laboratory, Pune, India
3 Department of Chemical and Petroleum Engineering, Center for Environmentally Beneficial Catalysis, The University of Kansas, Lawrence, KS, USA
Pages
231-238
Publication year
2010
Publication date
Sep 2010
ISSN
1011372X
e-ISSN
1572879X
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2258925522
Copyright
Catalysis Letters is a copyright of Springer, (2010). All Rights Reserved.