Details
Title
AAV-ie enables safe and efficient gene transfer to inner ear cells
Author
Tan, Fangzhi 1
; Chu, Cenfeng 2
; Qi, Jieyu 3 ; Li, Wenyan 4 ; You, Dan 4 ; Li, Ke 5 ; Chen, Xin 6 ; Zhao, Weidong 4 ; Cheng, Cheng 7 ; Liu, Xiaoyi 2 ; Qiao, Yunbo 8 ; Su, Bing 2 ; He, Shuijin 9 ; Zhong, Chao 10
; Li, Huawei 4 ; Chai, Renjie 11 ; Zhong, Guisheng 12
1 iHuman Institute, ShanghaiTech University, Shanghai, China
2 iHuman Institute, ShanghaiTech University, Shanghai, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China; University of the Chinese Academy of Sciences, Beijing, China
3 MOE Key Laboratory for Developmental Genes and Human Disease, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China; Co-innovation Center of Neuroregeneration, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, China
4 ENT Institute and Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Key Laboratory of Hearing Medicine of NHFPC, Shanghai Engineering Research Centre of Cochlear Implant, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
5 University of the Chinese Academy of Sciences, Beijing, China; School of Physical Science and Technology, ShanghaiTech University, Shanghai, China; Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China
6 School of Life Science and Technology, ShanghaiTech University, Shanghai, China; University of the Chinese Academy of Sciences, Beijing, China
7 Department of Otolaryngology Head and Neck Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu Provincial Key Medical Discipline (Laboratory), Nanjing, China; Research Institute of Otolaryngology, Nanjing, China
8 Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou, China
9 School of Life Science and Technology, ShanghaiTech University, Shanghai, China
10 School of Physical Science and Technology, ShanghaiTech University, Shanghai, China
11 MOE Key Laboratory for Developmental Genes and Human Disease, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China; Co-innovation Center of Neuroregeneration, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, China; ENT Institute and Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Key Laboratory of Hearing Medicine of NHFPC, Shanghai Engineering Research Centre of Cochlear Implant, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China; Institute for Stem Cell and Regeneration, Chinese Academy of Science, Beijing, China; Beijing Key Laboratory of Neural Regeneration and Repair, Capital Medical University, Beijing, China
12 iHuman Institute, ShanghaiTech University, Shanghai, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China; Co-innovation Center of Neuroregeneration, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, China
; Chu, Cenfeng 2
; Qi, Jieyu 3 ; Li, Wenyan 4 ; You, Dan 4 ; Li, Ke 5 ; Chen, Xin 6 ; Zhao, Weidong 4 ; Cheng, Cheng 7 ; Liu, Xiaoyi 2 ; Qiao, Yunbo 8 ; Su, Bing 2 ; He, Shuijin 9 ; Zhong, Chao 10
; Li, Huawei 4 ; Chai, Renjie 11 ; Zhong, Guisheng 12 1 iHuman Institute, ShanghaiTech University, Shanghai, China
2 iHuman Institute, ShanghaiTech University, Shanghai, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China; University of the Chinese Academy of Sciences, Beijing, China
3 MOE Key Laboratory for Developmental Genes and Human Disease, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China; Co-innovation Center of Neuroregeneration, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, China
4 ENT Institute and Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Key Laboratory of Hearing Medicine of NHFPC, Shanghai Engineering Research Centre of Cochlear Implant, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
5 University of the Chinese Academy of Sciences, Beijing, China; School of Physical Science and Technology, ShanghaiTech University, Shanghai, China; Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China
6 School of Life Science and Technology, ShanghaiTech University, Shanghai, China; University of the Chinese Academy of Sciences, Beijing, China
7 Department of Otolaryngology Head and Neck Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu Provincial Key Medical Discipline (Laboratory), Nanjing, China; Research Institute of Otolaryngology, Nanjing, China
8 Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou, China
9 School of Life Science and Technology, ShanghaiTech University, Shanghai, China
10 School of Physical Science and Technology, ShanghaiTech University, Shanghai, China
11 MOE Key Laboratory for Developmental Genes and Human Disease, Institute of Life Sciences, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, China; Co-innovation Center of Neuroregeneration, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, China; ENT Institute and Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Key Laboratory of Hearing Medicine of NHFPC, Shanghai Engineering Research Centre of Cochlear Implant, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China; Institute for Stem Cell and Regeneration, Chinese Academy of Science, Beijing, China; Beijing Key Laboratory of Neural Regeneration and Repair, Capital Medical University, Beijing, China
12 iHuman Institute, ShanghaiTech University, Shanghai, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China; Co-innovation Center of Neuroregeneration, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, China
Pages
1-10
Publication year
2019
Publication date
Aug 2019
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2275917826
Copyright
© 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.