Details
Title
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
Author
Gusach, Anastasiia 1
; Luginina, Aleksandra 1 ; Marin, Egor 1 ; Brouillette, Rebecca L 2 ; Élie Besserer-Offroy 2
; Longpré, Jean-Michel 2 ; Ishchenko, Andrii 3
; Popov, Petr 4 ; Patel, Nilkanth 5 ; Fujimoto, Taku 6 ; Maruyama, Toru 6 ; Stauch, Benjamin 7
; Ergasheva, Margarita 1 ; Romanovskaia, Daria 8
; Stepko, Anastasiia 1
; Kovalev, Kirill 9 ; Shevtsov, Mikhail 1 ; Gordeliy, Valentin 9 ; Han, Gye Won 7 ; Katritch, Vsevolod 10
; Borshchevskiy, Valentin 11
; Sarret, Philippe 2 ; Mishin, Alexey 1
; Cherezov, Vadim 12
1 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia
2 Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada
3 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA; Merck Research Laboratories, Merck & Co Inc., West Point, PA, USA
4 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Center for Computational and Data Intensive Science and Engineering, Skolkovo Institute of Science and Technology, Moscow, Russia
5 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
6 Ono Pharmaceutical Co., Ltd., Osaka, Japan
7 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA
8 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
9 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Center Jülich, Jülich, Germany; Institut de Biologie Structurale Jean-Pierre Ebel, Université Grenoble Alpes–Commissariat à l’Energie Atomique et aux Energies Alternatives–CNRS, Grenoble, France; JuStruct: Jülich Center for Structural Biology, Research Center Jülich, Jülich, Germany; Institute of Crystallography, RWTH Aachen University, Aachen, Germany
10 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA; Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
11 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Center Jülich, Jülich, Germany; JuStruct: Jülich Center for Structural Biology, Research Center Jülich, Jülich, Germany
12 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA; Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
; Luginina, Aleksandra 1 ; Marin, Egor 1 ; Brouillette, Rebecca L 2 ; Élie Besserer-Offroy 2
; Longpré, Jean-Michel 2 ; Ishchenko, Andrii 3
; Popov, Petr 4 ; Patel, Nilkanth 5 ; Fujimoto, Taku 6 ; Maruyama, Toru 6 ; Stauch, Benjamin 7
; Ergasheva, Margarita 1 ; Romanovskaia, Daria 8
; Stepko, Anastasiia 1
; Kovalev, Kirill 9 ; Shevtsov, Mikhail 1 ; Gordeliy, Valentin 9 ; Han, Gye Won 7 ; Katritch, Vsevolod 10
; Borshchevskiy, Valentin 11
; Sarret, Philippe 2 ; Mishin, Alexey 1
; Cherezov, Vadim 12
1 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia
2 Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada
3 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA; Merck Research Laboratories, Merck & Co Inc., West Point, PA, USA
4 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Center for Computational and Data Intensive Science and Engineering, Skolkovo Institute of Science and Technology, Moscow, Russia
5 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
6 Ono Pharmaceutical Co., Ltd., Osaka, Japan
7 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA
8 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
9 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Center Jülich, Jülich, Germany; Institut de Biologie Structurale Jean-Pierre Ebel, Université Grenoble Alpes–Commissariat à l’Energie Atomique et aux Energies Alternatives–CNRS, Grenoble, France; JuStruct: Jülich Center for Structural Biology, Research Center Jülich, Jülich, Germany; Institute of Crystallography, RWTH Aachen University, Aachen, Germany
10 Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA; Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
11 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Center Jülich, Jülich, Germany; JuStruct: Jülich Center for Structural Biology, Research Center Jülich, Jülich, Germany
12 Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia; Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA; Department of Chemistry, University of Southern California, Los Angeles, CA, USA; Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA
Pages
1-9
Publication year
2019
Publication date
Dec 2019
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2322188088
Copyright
© 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.