Abstract

The most important determinant of survival post-burn injury is wound healing. For decades, allogeneic mesenchymal stem cells (MSCs) have been suggested as a potential treatment for severe burn injuries. This report describes a patient with a severe burn injury whose wounds did not heal with over 18 months of conventional burn care. When treated with allogeneic MSCs, wound healing accelerated with no adverse treatment complications. Wound sites showed no evidence of keloids or hypertrophic formation during a 6-year follow-up period. This therapeutic use of allogeneic MSCs for large non-healing burn wounds was deemed safe and effective and has great treatment potential.

Details

Title
Allogeneic mesenchymal stem cells for treatment of severe burn injury
Author
Jeschke, Marc G; Rehou, Sarah; McCann, Matthew R; Shahrokhi, Shahriar
Pages
1-6
Section
Short report
Publication year
2019
Publication date
2019
Publisher
BioMed Central
e-ISSN
17576512
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2328546590
Copyright
© 2019. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.