Adipostatins A–D from Streptomyces sp. 4875 inhibiting Brugia malayi asparaginyl-tRNA synthetase and killing adult Brugia malayi parasites

Rateb, Mostafa E ¹ ; Yang, Dong ¹ ; Vodanovic-Jankovic, Sanja ² ; Yu, Zhiguo ¹ ; Kron, Michael A ² ; Shen, Ben <sup>3 

1</sup>  Department of Chemistry, The Scripps Research Institute, Jupiter, FL, USA 
²  Biotechnology and Bioengineering Center and Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA 
³  Department of Chemistry, The Scripps Research Institute, Jupiter, FL, USA; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL, USA; Natural Products Library Initiative, The Scripps Research Institute, Jupiter, FL, USA