Abstract

Background

Information on the prevalence of adjustment disorders among cancer patients and the value of psychological interventions in this group of patients is limited. This study investigates the prevalence of adjustment disorders among cancer patients as well as the reach, effectiveness, cost-utility and budget impact of a tailored psychological intervention.

Method

This study consists of two parts. Part 1 is an observational study among a representative group of mixed cancer patients after cancer treatment on the prevalence of adjustment disorder as well as the uptake (i.e. reach) of psychological treatment. In Part 2, patients diagnosed with an adjustment disorder are invited to participate in a randomized controlled trial. Patients will be randomized to the intervention (access to the tailored psychological intervention) or control group (waitlist period of 6 months). The psychological intervention consists of three modules: one module containing psycho-education (3 sessions, all patients) and two additional modules (maximum of 6 sessions per module) provided as continuum, in case needed. Module 2 and 3 can consist of several evidence-based interventions (e.g. group interventions, mindfulness, eHealth) The primary outcome is psychological distress (HADS). Secondary outcomes are mental adjustment to cancer (MAC) and health-related quality of life (EORTC QLQ-C30). To assess the cost-utility and budget impact, quality of life (EQ-5D-5 L) and costs (iMCQ and iPCQ) will be measured. Measures will be completed at baseline and 3 and 6-months after randomization.

Discussion

This study will provide data of the prevalence of adjustment disorders and the reach, effectiveness, cost-utility and budget impact of a tailored psychological intervention.

Trial registration

Netherlands Trial Register identifier: NL7763. Registered on 3 June 2019.

Details

Title
Prevalence of adjustment disorder among cancer patients, and the reach, effectiveness, cost-utility and budget impact of tailored psychological treatment: study protocol of a randomized controlled trial
Author
van Beek, Florie E; Wijnhoven, Lonneke M A; Jansen, Femke; Custers, José A E; Aukema, Eline J; Coupé, Veerle M H; Cuijpers, Pim; Marije L van der Lee; Lissenberg-Witte, Birgit I; Wijnen, Ben; Prins, Judith B; Verdonck-de Leeuw, Irma M
Pages
1-11
Section
Study protocol
Publication year
2019
Publication date
2019
Publisher
BioMed Central
e-ISSN
20507283
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s40359-019-0368-y
ProQuest document ID
2340806830
Copyright
© 2019. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.