Content area
Abstract
A red pigment produced by Zooshikella ganghwensis, was purified by solvent extraction and fractionation. The pigment was identified to be prodigiosin on the basis of spectroscopic data such as 1H-NMR, 13C-NMR, DEPT, 2D-NMR, IR, and FAB-MS. Prodigiosin inhibited matrix metalloproteinase-1 gene expression and the growth of human cancer cell lines, SK-BR-3, HCT-116, SK-OV-3, HeLa, HepG2, and SK-MEL-5.
Details
Title
Red pigment produced by Zooshikella ganghwensis inhibited the growth of human cancer cell lines and MMP-1 gene expression
Author
Eun-Ji, Oh 1 ; Jung-Hwa, Kwon 1 ; Su-Yeon, Kim 1 ; In Seo-Ji 1 ; Dong-Geol, Lee 2 ; Mi-Yeon, Cha 2 ; Kang Hee-Cheol 2 ; Hwang-Bo Jeon 1 ; Youn-Hyung, Lee 3 ; Chung In-Sik 1 ; Baek Nam-In 1
1 Kyung Hee University, Department of Oriental Medicine and Biotechnology, Graduate School of Biotechnology, Yongin, Republic of Korea (GRID:grid.289247.2) (ISNI:0000000121717818)
2 GFC Co., Ltd., Research and Development Center, Suwon, Republic of Korea (GRID:grid.289247.2)
3 Kyung Hee University, Department of Horticultural Biotechnology, Yongin, Republic of Korea (GRID:grid.289247.2) (ISNI:0000000121717818)
1 Kyung Hee University, Department of Oriental Medicine and Biotechnology, Graduate School of Biotechnology, Yongin, Republic of Korea (GRID:grid.289247.2) (ISNI:0000000121717818)
2 GFC Co., Ltd., Research and Development Center, Suwon, Republic of Korea (GRID:grid.289247.2)
3 Kyung Hee University, Department of Horticultural Biotechnology, Yongin, Republic of Korea (GRID:grid.289247.2) (ISNI:0000000121717818)
Pages
567-571
Publication year
2016
Publication date
Aug 2016
ISSN
24680834
e-ISSN
24680842
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2399163374
Copyright
© The Korean Society for Applied Biological Chemistry 2016.