Abstract

Background

Stroke can affect any portion of the central nervous system leading to a wide variety of symptoms depending on the part that is involved. Diffusion tensor imaging (DTI) is an emerging neuroimaging technique that allows measuring the integrity of white matter tracts.

Objectives

The objective of this study is to find out if the diffusion tensor tractography technique can provide prognostic information regarding clinical outcome following ischemic stroke.

Subjects and methods

Forty patients with acute ischemic stroke were studied with DTI. Size of infraction, degree of reduction of fractional anisotropy (FA), and pattern of corticospinal tract (CST) affection were identified. We assessed our patients according to the National Institute of Health Stroke Scale (NIHSS) and Medical Research Council (MRC) scale at onset of stroke and 3 months later.

Results

FA reduction was correlated with MRC and NIHSS on admission (P < 0.001, 0.004 respectively) and after 3 months (P < 0.001, 0.013 respectively). The pattern of CST affection was associated with NIHSS and MRC after 3 months (P = 0.035, 0.001 respectively).

Conclusion

DTI may be an indirect indicator of the ischemic stroke outcome.

Details

Title
Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke?
Author
Mostafa Mervat 1 ; Abdel Naseer Maged 1 ; Ramy, Edward 2 ; Edrees Mohammad 1 ; Labib, Dalia M 1 

 Cairo University, Department of Neurology, Cairo, Egypt (GRID:grid.7776.1) (ISNI:0000 0004 0639 9286) 
 Cairo University, Department of Radio-diagnosis, Cairo, Egypt (GRID:grid.7776.1) (ISNI:0000 0004 0639 9286) 
Publication year
2020
Publication date
Dec 2020
Publisher
Springer Nature B.V.
ISSN
11101083
e-ISSN
16878329
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2429904680
Copyright
© The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.