Content area
Full Text
Abstract
Background: The cases of mediastinal neurofibroma tumors without von Recklinghausen's disease are very rare. Clinical manifestations of tightness that do not get better with prolonged treatment using bronchodilators and steroids. After further examination and patient's history, a diagnosis of mediastinal mass can be established, that suppress the respiratory tract. Purpose: aim to know female patients of mediastinal neurofibroma without von recklinghausen's disease. Method: Old adult patients who experience mediastinal neurofibroma tumors with symptoms of shortness of breathing that are increasingly aggravated especially when cold and fatigue. Symptoms are related to compression or invasion directly to structures around the mediastinum or associated with paraneoplastic syndrome. Asymptomatic patients are usually associated with benign tumors and vice versa patients with symptomatic usually associated with malignancy. Result: The development of a malignant tumor occurs in 10% of cases of neurofibroma especially in patients with neurofibromatosis (von Recklinghausen's disease). The duration of ongoing disease coupled with complication from other diseases makes different alternatives the best indication. Conclusion: This tumor had reached the stage of surgical therapy to achieve safe and completed tumor excision. This therapy was carried out as an optimal effort to obtain a better prognosis for the patient's disease.
Keywords: Mediastinum Neurofibroma tumors, severe tightness, surgical therapy
INTRODUCTION
The prevalence of mediastinal neurogenic tumors is about 20-30% of all mediastinal tumors. Benign tumors are classified into two, namely schwannoma and neurofibroma(John, Larry, 2008).Schwannoma is the most common type of tumor (57.5%) and neurofibroma is a very rare case (18.9%). These two tumors usually develop in the posterior mediastinum (96.7%), and originate from intercostal, sympathetic or sometimes nerve vagus (Saito, et al. 2004). Almost all of these tumors are benign (70-80%), asymptomatic (40%), and found incidentally when checking routine x-rays (Rahman, et al. 2005; Saliu, et al, 2016).
The symptoms are usually related to compression or invasion directly to structures around the mediastinum or associated with paraneoplastic syndrome. Symptoms can include chest pain, coughing, tightness or neurological disorders. Asymptomatic patients are usually associated with benign tumors and vice versa patients with symptomatic usually associated malignancy (Divisi, et al. 1998) Chest CT scan is considered the main diagnostic modality in patients with posterior mediastinal tumors. however magnetic resonance imaging (MRI) can be best if there is an extension...