Tocolysis in preterm labour – current recommendations

Abstract

Common use of tocolytic drugs in preterm labor has not been shown to reduce the rate of neonatal mortality and morbidity. Currently, tocolytics should be administered in the course of a 48-h administration of antepartum glucocorticoids and/or transfer of the gravida to a center with neonatal intensive care unit. Only oxytocin receptor antagonist – atosiban and short-acting beta-agonists – fenoterol are licensed to reduce preterm uterine activity. Owing to its safety and efficacy, atosiban should be the first-choice tocolytic, especially in women with other diseases or multiple gestations.Tokoliza w porodzie przedwczesnym – aktualne wytyczne