Abstract

Background

Bariatric surgery is effective for the treatment of patients with morbid obesity and type 2 diabetes mellitus (T2DM), for body weight loss and glycemic control. However, in Japan, there has been no previous report of the effectiveness bariatric surgery in a case of morbid obesity associated with acute onset type 1 diabetes mellitus (T1DM), in which pancreatic β-cells were destroyed and endogenous insulin was depleted.

Case presentation

A 36-year-old woman with morbid obesity and T1DM, diagnosed when she was 6 years, was admitted for bariatric surgery. At her first consultation, she had a body weight of 106.7 kg and a body mass index of 42.2 kg/m2. Her HbA1c level was 9.0%, with a required daily insulin dose of 75 units. She underwent laparoscopic sleeve gastrectomy. At 1 year after surgery, her body weight had decreased to 81.0 kg and her body mass index to 32.2 kg/m2. In addition, her daily required dose of insulin had decreased to 24 units, with an improvement in her HbA1c level to 7.7%.

Conclusions

Although further evidence needs to be accumulated, including long-term outcomes, laparoscopic sleeve gastrectomy may provide an effective treatment for patients with morbid obesity and T1DM for body weight loss, improvement in HbA1c level, and insulin dose reduction.

Details

Title
Efficacy of laparoscopic sleeve gastrectomy for patient with morbid obesity and type 1 diabetes mellitus: a case report
Author
Ichikawa Hidetaka 1 ; Imoto Hirofumi 1   VIAFID ORCID Logo  ; Tanaka, Naoki 1 ; Musha Hiroaki 1 ; Sawada Shojiro 2 ; Naitoh Takeshi 3 ; Kamei Takashi 1 ; Unno Michiaki 1 

1  Tohoku University Graduate School of Medicine, Department of Surgery, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943) 
2  Tohoku University Graduate School of Medicine, Department of Metabolism and Diabetes, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943); Tohoku Medical and Pharmaceutical University, Department of Diabetes and Metabolism, Sendai, Japan (GRID:grid.412755.0) (ISNI:0000 0001 2166 7427) 
3  Tohoku University Graduate School of Medicine, Department of Surgery, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943); Kitasato University School of Medicine, Department of Colorectal Surgery, Sagamihara, Japan (GRID:grid.410786.c) (ISNI:0000 0000 9206 2938) 
Publication year
2021
Publication date
Jan 2021
Publisher
International Academic Publishing Co Ltd.
e-ISSN
21987793
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s40792-020-00989-5
ProQuest document ID
2475613905
Copyright
© The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.