Abstract
[...]exploring the effects and mechanisms of YXST in improving statin-induced muscle injury can be beneficial for the exercise rehabilitation and prognosis of patients with cardiovascular disease. Exercise capacity was evaluated at the end of the treatment using the running tolerance test (ZhiShuDuoBao, Beijing, China). [...]total cholesterol and creatine kinase concentrations were measured at the end of treatment. See PDF] Statins reduce exercise capacity, and long-term use can lead to decreased skeletal muscle strength and increased risk of falling in elderly patients.
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Details
1 Central Research Institute, Shanghai Pharmaceuticals Holding Co., Ltd., Shanghai 200120, China
2 Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 200120, China; Department of Pharmacology of Chinese Materia Medica, School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, Guangdong 510006, China
3 Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 200120, China
4 SPH Qingdao Growful Pharmaceutical Co., Ltd., Qingdao, Shandong 266510, China