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© 2021 Deng et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Studies on associations between Blastocystis and gut microbiota compositions. https://doi.org/10.1371/journal.ppat.1009253.t001 The beneficial associations of Blastocystis on gut microbiota A retrospective metagenomics approach to studying Blastocystis first revealed that the presence of Blastocystis was positively associated with the Prevotella- or Ruminococcus-driven enterotype and higher bacterial richness, whereas individuals with intestinal microbiota dominated by Bacteroides were much less likely to carry Blastocystis [16]. [...]the same research team verified these findings by analyzing another set of fecal samples, observing that individuals who were Blastocystis-colonized alone or along with Dientamoeba fragilis had relatively low abundance of Bacteroides and Clostridial cluster XIVa and high levels of Prevotella [17]. Nieves-Ramírez and colleagues [22] evaluated the fecal bacterial and eukaryotic microbiota from 156 asymptomatic adult subjects by amplification and sequencing of the 16S rRNA gene and 18S rRNA genes, respectively, and further compared the composition differences between Blastocystis-colonized and Blastocystis-free individuals. Blastocystis ST4 colonization in rats can increase the relative abundance of Oscillospira and decrease the level of Clostridium, which is linked to lower amounts of short-chain fatty acids (SCFAs) [45]. [...]ST3 and ST4 showed inverse (negative and positive, respectively) correlations to Akkermansia abundance in fecal samples from Flemish gut Flora Project (FgFP) [11], a bacteria that has been linked to delayed onset of obesity and its associated metabolic disorders in murine models [47].

Details

Title
New insights into the interactions between Blastocystis , the gut microbiota, and host immunity
Author
Deng, Lei; Lukasz Wojciech  VIAFID ORCID Logo  ; Gascoigne, Nicholas R J  VIAFID ORCID Logo  ; Peng, Guangneng; Tan, Kevin S W  VIAFID ORCID Logo 
First page
e1009253
Section
Review
Publication year
2021
Publication date
Feb 2021
Publisher
Public Library of Science
ISSN
15537366
e-ISSN
15537374
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2501885414
Copyright
© 2021 Deng et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.