Lactate detection sensors for food, clinical and biological applications: a review

Abstract

l-lactate is a major analyte in the food industry, bioprocess engineering, sports medicine and clinical care unit. l-lactate detection by standard analytical techniques is expensive, time-consuming and difficult for in situ studies. Therefore, selective l-lactate biosensors are developed to overcome the current challenges of food industries and biological sectors. High-throughput nanobiosensors appear promising for on-site detection of lactate in industrial- and laboratory-scale applications. Here, we review principles of lactate sensing techniques and trends in transduction approaches. We discuss nanomaterials, merits and demerits of enzyme-based lactate analysis and commercial testing kits. We present also non-enzymatic nanobiosensors.