Relax to grow more hair

Abstract

Since HFSCs were identified in the bulge region more than 30 years ago5-7, many regulatory molecules - such as gene-transcription factors and signalling proteins - have been shown to control the cells' quiescence and activation3,4. [...]although hair shedding in response to severe stress usually occurs during telogen, it is not well understood how a prolonged telogen contributes to the reduced anchorage of hair follicles, eventually leading to hair loss. [...]Choi et al. have shown that GAS6 promotes the expression of several genes involved in cell division in HFSCs, without interfering with known transcription factors and signalling pathways.