It appears you don't have support to open PDFs in this web browser. To view this file, Open with your PDF reader
Abstract
Eating disorders (EDs) in patients with Parkinson’s disease (PD) are mainly described through impulse control disorders but represent one end of the spectrum of food addiction (FA). Although not formally recognized by DSM-5, FA is well described in the literature on animal models and humans, but data on prevalence and risk factors compared with healthy controls (HCs) are lacking. We conducted a cross-sectional study including 200 patients with PD and 200 age- and gender-matched HCs. Characteristics including clinical data (features of PD/current medication) were collected. FA was rated using DSM-5 criteria and the Questionnaire on Eating and Weight Patterns-Revised (QEWP-R). Patients with PD had more EDs compared to HCs (27.0% vs. 13.0%, respectively, p < 0.001). They mainly had FA (24.5% vs. 12.0%, p = 0.001) and night eating syndrome (7.0% vs. 2.5% p = 0.03). In PD patients, FA was associated with female gender (p = 0.04) and impulsivity (higher attentional non-planning factor) but not with the dose or class of dopaminergic therapy. Vigilance is necessary, especially for PD women and in patients with specific impulsive personality traits. Counterintuitively, agonist dopaminergic treatment should not be used as an indication for screening FA in patients with PD.
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details
1 CHU Clermont-Ferrand, EA7280, Université Clermont Auvergne, Service de Psychiatrie B, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151)
2 CHU Clermont-Ferrand, EA7280, Université Clermont Auvergne, Service de Neurologie A, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151)
3 CHU Clermont-Ferrand, Unité de Biostatistiques (DRCI), Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151)
4 CHU Clermont-Ferrand, EA7280, Université Clermont Auvergne,, Explorations Fonctionnelles du Système Nerveux, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151)
5 CHU Clermont-Ferrand, Service de Nutrition Clinique, INRA, UMR 1019, UNH, CRNH Auvergne, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151); CHU Clermont-Ferrand, Centre Référent Troubles Des Conduites Alimentaires, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151)
6 CHU Clermont-Ferrand, EA7280, Université Clermont Auvergne, Service de Psychiatrie B, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151); CHU Clermont-Ferrand, EA7280, Université Clermont Auvergne, Service de Neurologie A, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151); CHU Clermont-Ferrand, Unité de Biostatistiques (DRCI), Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151); CHU Clermont-Ferrand, EA7280, Université Clermont Auvergne,, Explorations Fonctionnelles du Système Nerveux, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151); CHU Clermont-Ferrand, Service de Nutrition Clinique, INRA, UMR 1019, UNH, CRNH Auvergne, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151); CHU Clermont-Ferrand, Centre Référent Troubles Des Conduites Alimentaires, Clermont-Ferrand, France (GRID:grid.411163.0) (ISNI:0000 0004 0639 4151)