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Title
Identification of SARS-CoV-2-against aptamer with high neutralization activity by blocking the RBD domain of spike protein 1
Author
Yang, Ge 1 ; Li Ziyue 1 ; Mohammed, Irfan 1 ; Zhao, Liping 1 ; Wei, Wei 2 ; Xiao Haihua 3
; Guo Weisheng 4 ; Zhao Yongxiang 5
; Qu Feng 1 ; Huang Yuanyu 1
1 Beijing Institute of Technology, School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing, China (GRID:grid.43555.32) (ISNI:0000 0000 8841 6246)
2 Chinese Academy of Sciences, State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Beijing, China (GRID:grid.9227.e) (ISNI:0000000119573309)
3 Chinese Academy of Sciences, Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Beijing, China (GRID:grid.9227.e) (ISNI:0000000119573309)
4 Guangzhou Medical University, Translational Medicine Center, Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Second Affiliated Hospital, Guangzhou, China (GRID:grid.410737.6) (ISNI:0000 0000 8653 1072)
5 Guangxi Medical University, National Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research, Nanning, China (GRID:grid.256607.0) (ISNI:0000 0004 1798 2653)



1 Beijing Institute of Technology, School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing, China (GRID:grid.43555.32) (ISNI:0000 0000 8841 6246)
2 Chinese Academy of Sciences, State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Beijing, China (GRID:grid.9227.e) (ISNI:0000000119573309)
3 Chinese Academy of Sciences, Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Beijing, China (GRID:grid.9227.e) (ISNI:0000000119573309)
4 Guangzhou Medical University, Translational Medicine Center, Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Second Affiliated Hospital, Guangzhou, China (GRID:grid.410737.6) (ISNI:0000 0000 8653 1072)
5 Guangxi Medical University, National Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research, Nanning, China (GRID:grid.256607.0) (ISNI:0000 0004 1798 2653)
Publication year
2021
Publication date
2021
ISSN
20959907
e-ISSN
20593635
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2539746017
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.