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Abstract
Caffeine (120 mg/kg) was administered intragastrically to pregnant rats daily on gestational days 8-21. An increase in serum concentration of glucose and total protein was found in animals, which were given caffeine. The protein content proved to be highly significant in the experimental group of animals. The control group showed a negative interdependence between body weight gain and glucose concentration. No correlation was found between body weight gain and total protein concentration, yet the glucose concentration significantly influenced the total protein concentration in this group of animals. Among animals which received caffeine, correlations between total protein and glucose concentrations were observed. The analysis did not show that the glucose or total protein concentration significantly influenced the body weight gain of pregnant female rats in the experimental group. The research conducted suggests the possibility of modulating effects of caffeine on adaptive processes during pregnancy.
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Details
1 Department of Human Anatomy, Medical University in Lublin, 20-090 Lublin, Poland
2 Department of Animal Anatomy and Histology, University of Life Sciences in Lublin, 20-950 Lublin, Poland
3 Department of Biochemistry and Toxicology, University of Life Sciences in Lublin, 20-059 Lublin, Poland
4 Department of Nephrology, Medical University in Lublin, 20-090 Lublin, Poland
5 Department of Human Anatomy, Medical University in Lublin, 20-090 Lublin, Poland; Department of Radiology, St. John’s Cancer Center, 20-090 Lublin, Poland