Full text

Turn on search term navigation

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

The [Zn3(CitH)2] (1) (CitH4= citric acid), was dispersed in sodium lauryl sulphate (SLS) to form the micelle of SLS@[Zn3(CitH)2] (2). This material 2 was incorporated in hydrogel made by hydroxyethyl-methacrylate (HEMA), an ingredient of contact lenses, toward the formation of pHEMA@(SLS@[Zn3(CitH)2]) (3). Samples of 1 and 2 were characterized by UV-Vis, 1H-NMR, FT-IR, FT-Raman, single crystal X-ray crystallography, X-ray fluorescence analysis, atomic absorption and TG/DTA/DSC. The antibacterial activity of 13 as well as of SLS against Gram-positive (Staphylococcus epidermidis (St. epidermidis) and Staphylococcus aureus (St. aureus)) and Gram-negative (Pseudomonas aeruginosa (PAO1), and Escherichia coli (E. coli)) bacteria was evaluated by the means of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and inhibitory zone (IZ). 2 showed 10 to 20-fold higher activity than 1 against the bacteria tested. Moreover the 3 decreases the abundance of Gram-positive microbes up to 30% (St. aureus) and up to 20% (PAO1) the Gram-negative ones. The noteworthy antimicrobial activity of the obtained composite 3 suggests an effective antimicrobial additive for infection-free contact lenses.

Details

Title
An Efficient Disinfectant, Composite Material {SLS@[Zn3(CitH)2]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens
Author
Karetsi, V A 1 ; Banti, C N 1   VIAFID ORCID Logo  ; Kourkoumelis, N 2   VIAFID ORCID Logo  ; Papachristodoulou, C 3 ; Stalikas, C D 4 ; Raptopoulou, C P 5   VIAFID ORCID Logo  ; Psycharis, V 5   VIAFID ORCID Logo  ; Zoumpoulakis, P 6   VIAFID ORCID Logo  ; Mavromoustakos, T 7   VIAFID ORCID Logo  ; Sainis, I 8 ; Hadjikakou, S K 1   VIAFID ORCID Logo 

 Inorganic Chemistry laboratory, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece; [email protected] 
 Medical Physics Laboratory, Medical School, University of Ioannina, 45110 Ioannina, Greece; [email protected] 
 Department of Physics, University of Ioannina, 45110 Ioannina, Greece; [email protected] 
 Laboratory of Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece; [email protected] 
 Institute of Nanoscience and Nanotechnology, NCSR “Demokritos”, 15341 Athens, Greece[email protected] (V.P.) 
 Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, 11635 Athens, Greece; [email protected] 
 Organic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, 15571 Athens, Greece; [email protected] 
 Cancer Biobank Center, University of Ioannina, 45110 Ioannina, Greece; [email protected] 
First page
213
Publication year
2019
Publication date
2019
Publisher
MDPI AG
e-ISSN
20796382
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2545923144
Copyright
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.