Abstract

Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations (HFOs, > 80 Hz) and the epileptogenic zone, suggesting that HFOs can be a potential biomarker of epileptogenicity and epileptogenesis. This consensus includes the definition and standard detection techniques of HFOs, the localizing value of pathological HFOs for epileptic foci, and different ways to distinguish physiological from epileptic HFOs. The latest clinical applications of HFOs in epilepsy and the related findings are also discussed. HFOs will advance our understanding of the pathophysiology of epilepsy.

Details

Title
Expert consensus on clinical applications of high-frequency oscillations in epilepsy
Author
Wang, Yuping  VIAFID ORCID Logo  ; Zhou, Dong; Yang, Xiaofeng; Xu, Xin; Ren, Liankun; Yu, Tao; Zhou, Wenjing; Shao, Xiaoqiu; Yang, Zhixian; Wang, Shuang; Cao, Dezhi; Liu, Chunyan; Shang, Yeong Kwan; Xiang, Jing
Pages
1-10
Section
Consensus
Publication year
2020
Publication date
2020
Publisher
Nature Publishing Group
e-ISSN
25244434
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s42494-020-00018-w
ProQuest document ID
2546649589
Copyright
© 2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.