Left Bundle Branch Block and Mortality in COVID-19 Patients

Abstract

The prevalence of left bundle branch block (LBBB) in general population is commonly low but its prevalence significant increase in patients with chronic heart failure (HF).1 Recent analyses have demonstrated that COVID-19 patients have a significant incidence of acute HF while those with a history of chronic HF are prone to developing acute decompensation. [...]these patients frequently develop acute present cardiac injuries which significantly increase the risk of death during the infection.2 However, the prognostic role of LBBB in patients with SARS-CoV-2 infection has not yet been evaluated. Mortality risk data were pooled using the Mantel–Haenszel random effects models with odds ratio (OR) as the effect measure with 95% CI. Unfortunately, we were not able to assess if LBBB was already present before COVID-19 infection or it may be due to a cardiac complication/injury. [...]data regarding the prevalence of chronic HF were reported only two investigations not allowing a meta-regression for this variable.