Abstract

Background

Patients with acquired hemophilia A (AHA) who require open heart surgery have a life-threatening risk of hemorrhage. Limited data exist to guide perioperative management of these patients.

Case presentation

A 53-year-old female with rheumatoid arthritis, concomitant aortic valve endocarditis, and severe aortic regurgitation presented to our hospital. Bleeding and abnormal coagulation tests were noted during the initial workup, and she was diagnosed with AHA. The perioperative management plan included the use of pharmaceuticals, porcine recombinant factor VIII, and blood products. Extensive preoperative coagulation data were obtained, and factor VIII levels were continuously monitored to mitigate bleeding complications. The aortic valve replacement and root repair were uneventful.

Conclusion

Cardiac surgery in patients with AHA is possible as long as complex perioperative hemostatic and hematology management is used.

Details

Title
Aortic root repair in a patient with acquired hemophilia A: case report
Author
Gok Emre 1 ; Akay, Mehmet H 1 ; de Armas Ismael Salas 1 ; Klein, Kimberly 1 ; Hlaing, Tint 1 ; Allison, Paul M 2 ; Chen, Alice J 2 ; Akkanti Bindu 1 ; Kar Biswajit 1 ; Gregoric, Igor D 1   VIAFID ORCID Logo 

1  University of Texas Health Science Center at Houston, Center for Advanced Heart Failure, Houston, USA (GRID:grid.267308.8) (ISNI:0000 0000 9206 2401) 
2  Gulf Coast Pathology Associates, Houston, USA (GRID:grid.267308.8) 
Publication year
2021
Publication date
Dec 2021
Publisher
International Academic Publishing Co Ltd.
e-ISSN
21987793
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s40792-021-01256-x
ProQuest document ID
2557918209
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.