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ABSTRACT
In view of the importance of the biochemical aspect and its direct and indirect relationship with the various damage that occurs in different tissues, it has been necessary to study chemical changes in natural and pathological conditions.
The present study was conducted to evaluate the effect of active substances in the aqueous and alcoholic extracts of Nerium oleander on the Protoscolies viability of the echinococcus in vivo. The protoscolies were collected from livers of sheep naturally infected with Hydatid Cysts at Tikrit slaughterhouse. The viability of these Protoscolies was measured using the eosin aqueous stain. The results showed that there are significant differences in the concentrations of Nerium oleander for aqueous and alcoholic extracts. The alcoholic extract at a concentration of (270) mg / ml achieved good results, as the values of protein, glucose, triglycerides, urea, creatine, magnesium, sodium, potassium and zinc increased, while the values of liver enzymes GOT, GPT, and ALP decreased in the treated animals.
Keywords: Biochemical, oleander, hydatid cyst
Introduction
Hydatid cyst disease is one of the serious epidemiological health problems in most parts of the world (Eckert & Deplazes, 2004). It has several names: Echinococcosis, Cystic echinococcosis and Hydatidosis (Roberts & Janovy, 2000).
It is a Zoonotic disease, and the countries of the Middle East, North Africa, Sudan, the Caspian Sea Basin and some countries of South America are highly endemic to this disease (Wen et al., 1993). The disease in humans and other intermediate hosts (sheep, cows, buffaloes, camels, horses and other animals) results from the larval stage of the tapeworm parasites of Echinococcus, which includes many species, the most important of which is E. granulosus and the E. multilocularis and this stage can attack any organ in the body of the intermediate host. The disease is more common in rural areas where there are frequent breeding of farm animals and carnivores, which helps to complete the life cycle of this parasite that needs the middle host and the final host (dogs, wolves, hyenas, leopards and other wild animals) (Marquardt et al., 2).
Disease or epidemic in humans and other intermediate hosts is caused by ingestion of food and water contaminated with tapeworm eggs produced by adult parasitic worms in dogs. Currently, granulosus is the only type...