Abstract

Psoriasis is a chronic inflammatory skin disease that occurs in various forms throughout the body and is associated with certain conditions such as heart disease, diabetes, and depression. The psoriasis area severity index (PASI) score, a tool used to evaluate the severity of psoriasis, is currently used in clinical trials and clinical research. The determination of severity is based on the subjective judgment of the clinician. Thus, the disease evaluation deviations are induced. Therefore, we propose optimal algorithms that can effectively segment the lesion area and classify the severity. In addition, a new dataset on psoriasis was built, including patch images of erythema and scaling. We performed psoriasis lesion segmentation and classified the disease severity. In addition, we evaluated the best-performing segmentation method and classifier and analyzed features that are highly related to the severity of psoriasis. In conclusion, we presented the optimal techniques for evaluating the severity of psoriasis. Our newly constructed dataset improved the generalization performance of psoriasis diagnosis and evaluation. It proposed an optimal system for specific evaluation indicators of the disease and a quantitative PASI scoring method. The proposed system can help to evaluate the severity of localized psoriasis more accurately.

Details

Title
Optimization of psoriasis assessment system based on patch images
Author
Cho-I, Moon 1 ; Lee, Jiwon 1 ; Yoo HyunJong 2 ; Baek YooSang 3 ; Lee, Onseok 4 

 Soonchunhyang University, Department of Software Convergence, Graduate School, Asan City, Republic of Korea (GRID:grid.412674.2) (ISNI:0000 0004 1773 6524) 
 Soonchunhyang University, Department of Computer Science & Engineering, Graduate School, Asan City, Republic of Korea (GRID:grid.412674.2) (ISNI:0000 0004 1773 6524) 
 Guro Hospital, Korea University College of Medicine, Department of Dermatology, Seoul, Republic of Korea (GRID:grid.222754.4) (ISNI:0000 0001 0840 2678) 
 Soonchunhyang University, Department of Software Convergence, Graduate School, Asan City, Republic of Korea (GRID:grid.412674.2) (ISNI:0000 0004 1773 6524); Soonchunhyang University, Department of Medical IT Engineering, College of Medical Sciences, Asan City, Republic of Korea (GRID:grid.412674.2) (ISNI:0000 0004 1773 6524) 
Publication year
2021
Publication date
2021
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2572073861
Copyright
© The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.