Content area

Abstract

Meta-analysis is a common statistical method used to summarize multiple studies that cover the same topic. It can provide less biased results and explain heterogeneity between studies. Although there exists a variety of meta-analysis softwares, they are rarely both convenient to use and capable of comprehensive analytical functions. As a result, we are motivated to establish a meta-analysis web tool called Meta-Analysis Online (Onlinemeta). Onlinemeta includes three major modules: risk bias analysis, meta-analysis and network meta-analysis. The risk bias analysis module can produce heatmaps and histograms, whereas the meta-analysis module accepts many types of data as input, including dichotomous variables, single-armed dichotomous variables, continuous variables, single-armed continuous variables, survival data, deft method and diagnostic experiments, and outputs well-tuned forest plots, sensitivity analysis forest plots, funnel plots, comparison table of effects, SROC curve, and crosshair plots. For network meta-analysis module, the tool can process dichotomous variables or continuous variables, and generate network plots, forest plots, SUCRA (Surface Under the Cumulative Ranking) plots, rank plots and heatmaps. Onlinemeta is available at https://smuonco.Shinyapps.io/Onlinemeta/.

Competing Interest Statement

The authors have declared no competing interest.

Footnotes

* Figures revised to correct order and placement.

* https://smuonco.Shinyapps.io/Onlinemeta/

Details

1009240
Title
Onlinemeta: A Web Server for Meta-Analysis Based on Shiny Framework
Publication title
bioRxiv; Cold Spring Harbor
Publication year
2025
Publication date
Feb 14, 2025
Section
New Results
Publisher
Cold Spring Harbor Laboratory Press
Source
BioRxiv
Place of publication
Cold Spring Harbor
Country of publication
United States
University/institution
Cold Spring Harbor Laboratory Press
Publication subject
ISSN
2692-8205
Source type
Working Paper
Language of publication
English
Document type
Working Paper
Publication history
 
 
Milestone dates
2022-04-14 (Version 1); 2022-04-20 (Version 2); 2025-02-10 (Version 3)
ProQuest document ID
2650103976
Document URL
https://www.proquest.com/working-papers/onlinemeta-web-server-meta-analysis-based-on/docview/2650103976/se-2?accountid=208611
Copyright
© 2025. This article is published under http://creativecommons.org/licenses/by-nc/4.0/ (“the License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Last updated
2025-02-15
Database
ProQuest One Academic