Abstract

Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disease of the intestine, including Crohn’s disease (CD) and ulcerative colitis (UC), whose etiology and pathogenesis have not been fully understood. Due to its prolonged course and chronic recurrence, IBD imposes a heavy economic burden and psychological stress on patients. Traditional Chinese Herbal Medicine has unique advantages in IBD treatment because of its symptomatic treatment. However, the advantages of the Chinese Herbal Medicine Formula (CHMF) have rarely been discussed. In recent years, many scholars have conducted fundamental studies on CHMF to delay IBD from different perspectives and found that CHMF may help maintain intestinal integrity, reduce inflammation, and decrease oxidative stress, thus playing a positive role in the treatment of IBD. Therefore, this review focuses on the mechanisms associated with CHMF in IBD treatment. CHMF has apparent advantages. In addition to the exact composition and controlled quality of modern drugs, it also has multi-component and multi-target synergistic effects. CHMF has good prospects in the treatment of IBD, but its multi-agent composition and wide range of targets exacerbate the difficulty of studying its treatment of IBD. Future research on CHMF-related mechanisms is needed to achieve better efficacy.

Details

Title
Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment
Author
Yuan, Shuo; Wang, Qi; Jiao, Li; Jia-Chen, Xue; Li, You; Meng, Huan; Xiao-Ting, Hou; Ji-Xing, Nan; Qing-Gao, Zhang  VIAFID ORCID Logo 
Pages
1-17
Section
Review
Publication year
2022
Publication date
2022
Publisher
BioMed Central
ISSN
17498546
e-ISSN
1749-8546
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2678134335
Copyright
© 2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.