Abstract

Dyslipidemia is one of the complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and it is often underestimated and undertreated. Dyslipidemia in allo-HSCT recipients has been confirmed to be associated with endocrine dysfunction, acute and chronic graft-versus-host disease (aGVHD and cGVHD), immunosuppressive agent application, etc. However, few studies have illustrated the accurate molecular signaling pathways involved in dyslipidemia, and there are no standard guidelines for dyslipidemia management after HSCT. This review will discuss the pathogenesis of dyslipidemia, especially the association with aGVHD and/or cGVHD. Comprehensive treatment methods for dyslipidemia after HSCT will also be summarized.

Details

Title
Management of dyslipidemia after allogeneic hematopoietic stem cell transplantation
Author
Lu, Yingxue; Ma, Xiaojing; Pan, Jie; Ma, Rongqiang; Jiang, Yujie
Pages
1-13
Section
Review
Publication year
2022
Publication date
2022
Publisher
BioMed Central
e-ISSN
1476511X
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2704082711
Copyright
© 2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.