It appears you don't have support to open PDFs in this web browser. To view this file, Open with your PDF reader
Abstract
Despite its physiological and pathological importance, the mechanical relationship between glucose uptake in the intestine and intestinal flows is unclear. In the intestine of the nematode Caenorhabditis elegans, the defecation motor program (DMP) causes reciprocating intestinal flows. Although the DMP is frequently activated in the intestines, its physiological function is unknown. We evaluated the mechanical signature of enhanced glucose uptake by the DMP in worms. Glucose uptake tended to increase with increasing flow velocity during the DMP because of mechanical mixing and transport. However, the increase in input energy required for the DMP was low compared with the calorie intake. The findings suggest that animals with gastrointestinal motility exploit the reciprocating intestinal flows caused by peristalsis to promote nutrient absorption by intestinal cells.
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details
1 Tohoku University, Graduate School of Engineering, Department of Finemechanics, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943)
2 Tohoku University, Graduate School of Engineering, Department of Finemechanics, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943); Tohoku University, Graduate School of Biomedical Engineering, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943)
3 Tohoku University, Graduate School of Biomedical Engineering, Sendai, Japan (GRID:grid.69566.3a) (ISNI:0000 0001 2248 6943)