Content area

Abstract

In the biomedical literature, gene pathways are frequently included. Many high-quality gene pathways are illustrated in the form of visuals and text, making them valuable study tools for biological processes and precision medicine. Pathway maps and literature texts provide researchers with access to a huge number of new biological treatments. For general usage, these pathway maps should be logically ordered, coordinated, and converted into a computer-readable format. Currently, keeping up with the rapid increase of the literature requires the laborious extraction of information from a publication at a time.

A gene pathway map recognition system is devised and implemented in this study. Based on the pathway map and relevant information supplied by users, the system extracts gene identity and gene interaction information, and the automated extraction from pathway maps is efficient. Furthermore, the tool offers users a full view of a certain illness’s pathway, which is useful for researchers and can speed up the research process in a variety of biomedical applications.

This thesis first explains the project's goal and provides background information. The project's design ideas are then presented, as well as an analysis of the system and introductions to related platforms. After that, the system's implementations are described one by one, together with the deployment and testing processes. Finally, potential improvements and future work are discussed.

Details

1010268
Title
Pathway Curator: An Online Webserver for Extracting Genes and Interactions from Figures
Number of pages
86
Publication year
2022
Degree date
2022
School code
0133
Source
MAI 84/3(E), Masters Abstracts International
ISBN
9798351462240
Advisor
Committee member
Popescu, Mihail; Duan, Ye
University/institution
University of Missouri - Columbia
Department
Computer Science
University location
United States -- Missouri
Degree
M.S.
Source type
Dissertation or Thesis
Language
English
Document type
Dissertation/Thesis
Dissertation/thesis number
29167887
ProQuest document ID
2725640625
Document URL
https://www.proquest.com/dissertations-theses/pathway-curator-online-webserver-extracting-genes/docview/2725640625/se-2?accountid=208611
Copyright
Database copyright ProQuest LLC; ProQuest does not claim copyright in the individual underlying works.
Database
ProQuest One Academic