Abstract
Background
The sequence of establishing a proximal stability or function before facilitation of the distal body part has long been recognized in stroke rehabilitation practice but lacks scientific evidence. This study plans to examine the effects of proximal priority robotic priming and impairment-oriented training (PRI) and distal priority robotic priming and impairment-oriented training (DRI).
Methods
This single-blind, randomized, comparative efficacy study will involve 40 participants with chronic stroke. Participants will be randomized into the PRI or DRI groups and receive 18 intervention sessions (90 min/day, 3 days/weeks for 6 weeks). The Fugl-Meyer Assessment Upper Extremity subscale, Medical Research Council Scale, Revised Nottingham Sensory Assessment, and Wolf Motor Function Test will be administered at baseline, after treatment, and at the 3-month follow-up. Two-way repeated-measures analysis of variance and the chi-square automatic interaction detector method will be used to examine the comparative efficacy and predictors of outcome, respectively, after PRI and DRI.
Discussion
Through manipulating the sequence of applying wrist and forearm robots in therapy, this study will attempt to examine empirically the priming effect of proximal or distal priority robotic therapy in upper extremity impairment-oriented training for people with stroke. The findings will provide directions for further studies and empirical implications for clinical practice in upper extremity rehabilitation after stroke.
Trial Registration
ClinicalTrials.gov NCT04446273. Registered on June 23, 2020.
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Details
; Chen, Chia-ling 3 ; Wu, Yi-hsuan 4 ; Kuo, Chihchieh 5 ; Yeh, Yi-ping 1 ; Liu, Ting-xuan 1 1 National Taiwan University, School of Occupational Therapy, College of Medicine, Taipei City, Taiwan (GRID:grid.19188.39) (ISNI:0000 0004 0546 0241)
2 National Taiwan University, School of Occupational Therapy, College of Medicine, Taipei City, Taiwan (GRID:grid.19188.39) (ISNI:0000 0004 0546 0241); National Taiwan University Hospital, Division of Occupational Therapy, Department of Physical Medicine and Rehabilitation, Taipei City, Taiwan (GRID:grid.412094.a) (ISNI:0000 0004 0572 7815)
3 Graduate Institute of Early Intervention, Chang Gung University, Taoyuan City, Taiwan (GRID:grid.145695.a); Linkou Chang Gung Memorial Hospital, Department of Physical Medicine and Rehabilitation, Taoyuan City, Taiwan (GRID:grid.454211.7) (ISNI:0000 0004 1756 999X)
4 National Taiwan University Hospital, Division of Occupational Therapy, Department of Physical Medicine and Rehabilitation, Taipei City, Taiwan (GRID:grid.412094.a) (ISNI:0000 0004 0572 7815)
5 Ministry of Health and Welfare, Rehabilitation Department, Feng Yuan Hospital, Taichung City, Taiwan (GRID:grid.454740.6)




