Abstract

The coronavirus disease 2019 (COVID-19) pandemic resulted in severe interruptions to clinical research worldwide. This global public health crisis required investigators and researchers to rapidly develop and implement new strategies and solutions to mitigate its negative impact on the progress of clinical trials. In this paper, we describe the challenges, strategies, and lessons learned regarding the continuation of a supportive oncology clinical trial during the pandemic. We hope to provide insight into the implementation of clinical trials during a public health emergency to be better prepared for future instances.

Trial registration: ClinicalTrials.gov, a service of the US National Institute of Health (NCT 03030859). Registered on 22 January 2017.

Details

Title
Conducting a supportive oncology clinical trial during the COVID-19 pandemic: challenges and strategies
Author
Deng, Jie 1   VIAFID ORCID Logo  ; Lukens, John N. 1 ; Cohn, Joy C. 1 ; McMenamin, Erin 1 ; Murphy, Barbara 2 ; Spinelli, Bryan A. 3 ; Murphy, Niya 1 ; Steinmetz, Alicia K. 1 ; Landriau, Megan A. 1 ; Lin, Alexander 1 

1  University of Pennsylvania, Philadelphia, USA (GRID:grid.25879.31) (ISNI:0000 0004 1936 8972) 
2  Vanderbilt-Ingram Cancer Center, Nashville, USA (GRID:grid.412807.8) (ISNI:0000 0004 1936 9916) 
3  Thomas Jefferson University, Philadelphia, USA (GRID:grid.265008.9) (ISNI:0000 0001 2166 5843) 
Pages
927
Publication year
2022
Publication date
Dec 2022
Publisher
Springer Nature B.V.
e-ISSN
17456215
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s13063-022-06804-w
ProQuest document ID
2733859834
Copyright
© The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.