Abstract

The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the environment. This paper proposes a biomimetic ocular prosthesis system that mimics the human light modulation response capable of pupil and corneal reflections. First, photoinduced synaptic properties of the quantum dot embedded photonic synapse and its biosimilar signal transmission is confirmed. Subsequently, the pupillary light reflex is emulated by incorporating the quantum dot embedded photonic synapse, electrochromic device, and CMOS components. Moreover, a solenoid-based eyelid is connected to the pupillary light reflex system to emulate the corneal reflex. The proposed ocular prosthesis system represents a platform for biomimetic prosthesis that can accommodate an appropriate amount of stimulus by self-regulating the intensity of external stimuli.

The adoption of photonic synapses with biosimilarity to realize analog signal transmission is of significance in realizing artificial illuminance modulation responses. Here, the authors report a biomimetic ocular prosthesis system based on quantum dots embedded photonic synapses with improved depression properties through mid-gap trap.

Details

Title
A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections
Author
Kim, Seongchan 1 ; Choi, Yoon Young 2 ; Kim, Taewan 3   VIAFID ORCID Logo  ; Kim, Yong Min 4   VIAFID ORCID Logo  ; Ho, Dong Hae 5 ; Choi, Young Jin 6 ; Roe, Dong Gue 7 ; Lee, Ju-Hee 8 ; Park, Joongpill 9 ; Choi, Ji-Woong 10 ; Kim, Jeong Won 10   VIAFID ORCID Logo  ; Park, Jin-Hong 11   VIAFID ORCID Logo  ; Jo, Sae Byeok 12   VIAFID ORCID Logo  ; Moon, Hong Chul 4   VIAFID ORCID Logo  ; Jeong, Sohee 3   VIAFID ORCID Logo  ; Cho, Jeong Ho 6   VIAFID ORCID Logo 

1  Sungkyunkwan University, SKKU Advanced Institute of Nanotechnology (SAINT), Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X); The Pennsylvania State University, Department of Engineering Science and Mechanics, University Park, USA (GRID:grid.29857.31) (ISNI:0000 0001 2097 4281) 
2  University of Illinois at Urbana Champaign, Department of Mechanical Science and Engineering, Urbana, USA (GRID:grid.35403.31) (ISNI:0000 0004 1936 9991) 
3  Sungkyunkwan University, Department of Energy Science and Center for Artificial Atoms, Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X); Sungkyunkwan University, Sungkyun Institute of Energy Science and Technology (SIEST), Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X) 
4  University of Seoul, Department of Chemical Engineering, Seoul, Korea (GRID:grid.267134.5) (ISNI:0000 0000 8597 6969) 
5  Soft Materials and Structures Lab, Virginia Tech, Mechanical Engineering, Blacksburg, USA (GRID:grid.438526.e) (ISNI:0000 0001 0694 4940) 
6  Yonsei University, Department of Chemical and Biomolecular Engineering, Seoul, Korea (GRID:grid.15444.30) (ISNI:0000 0004 0470 5454) 
7  Yonsei University, School of Electrical and Electronic Engineering, Seoul, Korea (GRID:grid.15444.30) (ISNI:0000 0004 0470 5454) 
8  Sungkyunkwan University, Department of Electrical and Computer Engineering, Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X) 
9  Sungkyunkwan University, Department of Energy Science and Center for Artificial Atoms, Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X) 
10  Korea Research Institute of Standards and Science (KRISS), Daejeon, Korea (GRID:grid.410883.6) (ISNI:0000 0001 2301 0664) 
11  Sungkyunkwan University, SKKU Advanced Institute of Nanotechnology (SAINT), Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X); Sungkyunkwan University, Department of Electrical and Computer Engineering, Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X) 
12  Sungkyunkwan University (SKKU), School of Chemical Engineering, Suwon, Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X) 
Publication year
2022
Publication date
2022
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41467-022-34448-6
ProQuest document ID
2734481511
Copyright
© The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.