Abstract

Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-control samples from 36 different tumor types aggregated within the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium to characterize the genomic footprints of these mechanisms. While the telomere content of tumors with ATRX or DAXX mutations (ATRX/DAXXtrunc) is increased, tumors with TERT modifications show a moderate decrease of telomere content. One quarter of all tumor samples contain somatic integrations of telomeric sequences into non-telomeric DNA. This fraction is increased to 80% prevalence in ATRX/DAXXtrunc tumors, which carry an aberrant telomere variant repeat (TVR) distribution as another genomic marker. The latter feature includes enrichment or depletion of the previously undescribed singleton TVRs TTCGGG and TTTGGG, respectively. Our systematic analysis provides new insight into the recurrent genomic alterations associated with telomere maintenance mechanisms in cancer.

In somatic cells the mechanisms maintaining the chromosome ends are normally inactivated; however, cancer cells can re-activate these pathways to support continuous growth. Here, the authors characterize the telomeric landscapes across tumour types and identify genomic alterations associated with different telomere maintenance mechanisms.

Details

Title
Genomic footprints of activated telomere maintenance mechanisms in cancer
Author
Sieverling, Lina 1   VIAFID ORCID Logo  ; Hong, Chen 1   VIAFID ORCID Logo  ; Koser, Sandra D. 1 ; Ginsbach, Philip 2 ; Kleinheinz, Kortine 3 ; Hutter, Barbara 4   VIAFID ORCID Logo  ; Braun, Delia M. 5   VIAFID ORCID Logo  ; Cortés-Ciriano, Isidro 6   VIAFID ORCID Logo  ; Xi, Ruibin 7   VIAFID ORCID Logo  ; Kabbe, Rolf 2 ; Park, Peter J. 8   VIAFID ORCID Logo  ; Eils, Roland 3 ; Schlesner, Matthias 9   VIAFID ORCID Logo  ; Akdemir, Kadir C. 10 ; Alvarez, Eva G. 11 ; Baez-Ortega, Adrian 12 ; Beroukhim, Rameen 13 ; Boutros, Paul C. 14 ; Bowtell, David D. L. 15 ; Brors, Benedikt 16 ; Burns, Kathleen H. 17 ; Campbell, Peter J. 18 ; Chan, Kin 19 ; Chen, Ken 10 ; Dueso-Barroso, Ana 20 ; Dunford, Andrew J. 21 ; Edwards, Paul A. 22 ; Estivill, Xavier 23 ; Etemadmoghadam, Dariush 15 ; Feuerbach, Lars 24 ; Fink, J. Lynn 25 ; Frenkel-Morgenstern, Milana 26 ; Garsed, Dale W. 15 ; Gerstein, Mark 27 ; Gordenin, Dmitry A. 28 ; Haan, David 29 ; Haber, James E. 30 ; Hess, Julian M. 31 ; Imielinski, Marcin 32 ; Jones, David T. W. 33 ; Ju, Young Seok 34 ; Kazanov, Marat D. 35 ; Klimczak, Leszek J. 36 ; Koh, Youngil 37 ; Korbel, Jan O. 38 ; Kumar, Kiran 21 ; Lee, Eunjung Alice 39 ; Lee, Jake June-Koo 40 ; Li, Yilong 41 ; Lynch, Andy G. 42 ; Macintyre, Geoff 43 ; Markowetz, Florian 22 ; Martincorena, Iñigo 41 ; Martinez-Fundichely, Alexander 44 ; Meyerson, Matthew 45 ; Miyano, Satoru 46 ; Nakagawa, Hidewaki 47 ; Navarro, Fabio C. P. 48 ; Ossowski, Stephan 49 ; Pearson, John V. 50 ; Puiggròs, Montserrat 20 ; Rippe, Karsten 51 ; Roberts, Nicola D. 41 ; Roberts, Steven A. 52 ; Rodriguez-Martin, Bernardo 11 ; Schumacher, Steven E. 53 ; Scully, Ralph 54 ; Shackleton, Mark 55 ; Sidiropoulos, Nikos 56 ; Stewart, Chip 21 ; Torrents, David 57 ; Tubio, Jose M. C. 11 ; Villasante, Izar 20 ; Waddell, Nicola 50 ; Wala, Jeremiah A. 58 ; Weischenfeldt, Joachim 59 ; Yang, Lixing 60 ; Yao, Xiaotong 61 ; Yoon, Sung-Soo 62 ; Zamora, Jorge 63 ; Zhang, Cheng-Zhong 64 ; Aaltonen, Lauri A. 65 ; Abascal, Federico 66 ; Abeshouse, Adam 67 ; Aburatani, Hiroyuki 68 ; Adams, David J. 66 ; Agrawal, Nishant 69 ; Ahn, Keun Soo 70 ; Ahn, Sung-Min 71 ; Aikata, Hiroshi 72 ; Akbani, Rehan 73 ; Al-Ahmadie, Hikmat 67 ; Al-Sedairy, Sultan T. 74 ; Al-Shahrour, Fatima 75 ; Alawi, Malik 76 ; Albert, Monique 77 ; Aldape, Kenneth 78 ; Alexandrov, Ludmil B. 79 ; Ally, Adrian 80 ; Alsop, Kathryn 81 ; Amary, Fernanda 82 ; Amin, Samirkumar B. 83 ; Aminou, Brice 84 ; Ammerpohl, Ole 85 ; Anderson, Matthew J. 86 ; Ang, Yeng 87 ; Antonello, Davide 88 ; Anur, Pavana 89 ; Aparicio, Samuel 90 ; Appelbaum, Elizabeth L. 91 ; Arai, Yasuhito 92 ; Aretz, Axel 93 ; Arihiro, Koji 72 ; Ariizumi, Shun-ichi 94 ; Armenia, Joshua 95 ; Arnould, Laurent 96 ; Asa, Sylvia 97 ; Assenov, Yassen 98 ; Atwal, Gurnit 99 ; Aukema, Sietse 100 ; Auman, J. 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Steven 159 ; Bowen, David T. 160 ; Bowlby, Reanne 80 ; Boyault, Sandrine 161 ; Boyce, Rich 116 ; Boyd, Jeffrey 162 ; Brazma, Alvis 116 ; Brennan, Paul 163 ; Brewer, Daniel S. 164 ; Brinkman, Arie B. 165 ; Bristow, Robert G. 166 ; Broaddus, Russell R. 167 ; Brock, Jane E. 168 ; Brock, Malcolm 169 ; Broeks, Annegien 170 ; Brooks, Angela N. 171 ; Brooks, Denise 80 ; Brunak, Søren 172 ; Bruxner, Timothy J. 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Dei 245 ; Delaneau, Olivier 246 ; Demchok, John A. 185 ; Demeulemeester, Jonas 247 ; Demidov, German M. 248 ; Demircioğlu, Deniz 249 ; Dennis, Nening M. 186 ; Denroche, Robert E. 120 ; Dentro, Stefan C. 250 ; Desai, Nikita 251 ; Deshpande, Vikram 144 ; Deshwar, Amit G. 252 ; Desmedt, Christine 253 ; Deu-Pons, Jordi 254 ; Dhalla, Noreen 80 ; Dhani, Neesha C. 255 ; Dhingra, Priyanka 256 ; Dhir, Rajiv 257 ; DiBiase, Anthony 258 ; Diamanti, Klev 259 ; Ding, Li 260 ; Ding, Shuai 261 ; Dinh, Huy Q. 262 ; Dirix, Luc 263 ; Doddapaneni, HarshaVardhan 229 ; Donmez, Nilgun 264 ; Dow, Michelle T. 207 ; Drapkin, Ronny 265 ; Drechsel, Oliver 266 ; Drews, Ruben M. 267 ; Serge, Serge 66 ; Dudderidge, Tim 268 ; Dunn, Michael 269 ; Dursi, Lewis Jonathan 270 ; Duthie, Fraser R. 271 ; Dutton-Regester, Ken 272 ; Eagles, Jenna 236 ; Easton, Douglas F. 273 ; Edmonds, Stuart 274 ; Edwards, Sandra E. 149 ; Eeles, Rosalind A. 275 ; Ehinger, Anna 276 ; Eils, Juergen 277 ; El-Naggar, Adel 237 ; Eldridge, Matthew 267 ; Ellrott, Kyle 175 ; Erkek, Serap 278 ; Escaramis, Georgia 279 ; Espiritu, Shadrielle M. G. 113 ; Eyfjord, Jorunn E. 280 ; Faltas, Bishoy M. 281 ; Fan, Daiming 282 ; Fan, Yu 73 ; Faquin, William C. 144 ; Farcas, Claudiu 207 ; Fassan, Matteo 283 ; Fatima, Aquila 284 ; Favero, Francesco 285 ; Fayzullaev, Nodirjon 84 ; Felau, Ina 185 ; Fereday, Sian 81 ; Ferguson, Martin L. 286 ; Ferretti, Vincent 287 ; Field, Matthew A. 288 ; Finocchiaro, Gaetano 289 ; Fisher, Cyril 186 ; Fittall, Matthew W. 290 ; Fitzgerald, Anna 291 ; Fitzgerald, Rebecca C. 292 ; Flanagan, Adrienne M. 293 ; Fleshner, Neil E. 294 ; Flicek, Paul 116 ; Foekens, John A. 295 ; Fong, Kwun M. 296 ; Fonseca, Nuno A. 297 ; Foster, Christopher S. 298 ; Fox, Natalie S. 113 ; Fraser, Michael 113 ; Frazer, Scott 21 ; Friedman, William 299 ; Frigola, Joan 300 ; Fronick, Catrina C. 227 ; Fujimoto, Akihiro 47 ; Fujita, Masashi 47 ; Fukayama, Masashi 301 ; Fulton, Lucinda A. 302 ; Fulton, Robert S. 260 ; Furuta, Mayuko 47 ; Futreal, P. Andrew 303 ; Füllgrabe, Anja 116 ; Gabriel, Stacey B. 21 ; Gallinger, Steven 304 ; Gambacorti-Passerini, Carlo 305 ; Gao, Jianjiong 95 ; Gao, Shengjie 306 ; Garraway, Levi 307 ; Garred, Øystein 308 ; Garrison, Erik 66 ; Gehlenborg, Nils 309 ; Gelpi, Josep L. L. 310 ; George, Joshy 311 ; Gerhard, Daniela S. 312 ; Gerhauser, Clarissa 313 ; Gershenwald, Jeffrey E. 314 ; Gerstung, Moritz 187 ; Getz, Gad 315 ; Ghori, Mohammed 66 ; Ghossein, Ronald 316 ; Giama, Nasra H. 317 ; Gibbs, Richard A. 229 ; Gibson, Bob 318 ; Gill, Anthony J. 319 ; Gill, Pelvender 320 ; Giri, Dilip D. 316 ; Glodzik, Dominik 66 ; Gnanapragasam, Vincent J. 321 ; Goebler, Maria Elisabeth 322 ; Goldman, Mary J. 231 ; Gomez, Carmen 323 ; Gonzalez, Santiago 187 ; Gonzalez-Perez, Abel 324 ; Gossage, James 325 ; Gotoh, Kunihito 326 ; Govindan, Ramaswamy 327 ; Grabau, Dorthe 328 ; Graham, Janet S. 329 ; Grant, Robert C. 330 ; Green, Anthony R. 331 ; Green, Eric 332 ; Greger, Liliana 116 ; Grehan, Nicola 292 ; Grimaldi, Sonia 148 ; Grimmond, Sean M. 333 ; Grossman, Robert L. 334 ; Grundhoff, Adam 335 ; Gundem, Gunes 67 ; Guo, Qianyun 336 ; Gupta, Manaswi 21 ; Gupta, Shailja 337 ; Gut, Ivo G. 127 ; Gut, Marta 127 ; Göke, Jonathan 338 ; Ha, Gavin 21 ; Haake, Andrea 339 ; Haas, Siegfried 340 ; Haase, Kerstin 290 ; Habermann, Nina 278 ; Hach, Faraz 341 ; Haider, Syed 113 ; Hama, Natsuko 92 ; Hamdy, Freddie C. 320 ; Hamilton, Anne 230 ; Hamilton, Mark P. 342 ; Han, Leng 343 ; Hanna, George B. 344 ; Hansmann, Martin 345 ; Haradhvala, Nicholas J. 346 ; Harismendy, Olivier 347 ; Harliwong, Ivon 86 ; Harmanci, Arif O. 348 ; Harrington, Eoghan 349 ; Hasegawa, Takanori 350 ; Haussler, David 351 ; Hawkins, Steve 267 ; Hayami, Shinya 352 ; Hayashi, Shuto 350 ; Hayes, D. 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M. Ashiqul 207 ; Ittmann, Michael 392 ; Ivkovic, Sinisa 243 ; Izarzugaza, Jose M. G. 393 ; Jacquemier, Jocelyne 394 ; Jakrot, Valerie 179 ; Jamieson, Nigel B. 395 ; Jang, Gun Ho 120 ; Jang, Se Jin 396 ; Jayaseelan, Joy C. 229 ; Jayasinghe, Reyka 302 ; Jefferys, Stuart R. 108 ; Jegalian, Karine 397 ; Jennings, Jennifer L. 398 ; Jeon, Seung-Hyup 212 ; Jerman, Lara 399 ; Ji, Yuan 400 ; Jiao, Wei 113 ; Johansson, Peter A. 272 ; Johns, Amber L. 401 ; Johns, Jeremy 236 ; Johnson, Rory 402 ; Johnson, Todd A. 403 ; Jolly, Clemency 290 ; Joly, Yann 404 ; Jonasson, Jon G. 280 ; Jones, Corbin D. 405 ; Jones, David R. 66 ; Jones, Nic 406 ; Jones, Steven J. 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A. 2 ; Khoo, David 425 ; Khoo, Vincent 186 ; Khuntikeo, Narong 426 ; Khurana, Ekta 427 ; Kilpinen, Helena 420 ; Kim, Hark Kyun 428 ; Kim, Hyung-Lae 429 ; Kim, Hyung-Yong 394 ; Kim, Hyunghwan 212 ; Kim, Jaegil 21 ; Kim, Jihoon 430 ; Kim, Jong K. 431 ; Kim, Youngwook 432 ; King, Tari A. 433 ; Klapper, Wolfram 434 ; Knappskog, Stian 435 ; Kneba, Michael 416 ; Knoppers, Bartha M. 404 ; Komorowski, Jan 436 ; Komura, Daisuke 391 ; Komura, Mitsuhiro 350 ; Kong, Gu 394 ; Kool, Marcel 437 ; Korchina, Viktoriya 229 ; Korshunov, Andrey 438 ; Koscher, Michael 438 ; Koster, Roelof 439 ; Kote-Jarai, Zsofia 149 ; Koures, Antonios 207 ; Kovacevic, Milena 243 ; Kremeyer, Barbara 66 ; Kretzmer, Helene 440 ; Kreuz, Markus 441 ; Krishnamurthy, Savitri 442 ; Kube, Dieter 443 ; Kumar, Pardeep 186 ; Kumar, Sushant 444 ; Kumar, Yogesh 381 ; Kundra, Ritika 206 ; Kübler, Kirsten 445 ; Küppers, Ralf 446 ; Lagergren, Jesper 447 ; Lai, Phillip H. 135 ; Laird, Peter W. 448 ; Lakhani, Sunil R. 449 ; Lalansingh, Christopher M. 113 ; Lalonde, Emilie 113 ; Lamaze, Fabien C. 113 ; Lambert, Adam 320 ; Lander, Eric 21 ; Landgraf, Pablo 450 ; Landoni, Luca 88 ; Langerød, Anita 102 ; Lanzós, Andrés 451 ; Larsimont, Denis 452 ; Larsson, Erik 453 ; Lathrop, Mark 454 ; Lau, Loretta M. S. 455 ; Lawerenz, Chris 456 ; Lawlor, Rita T. 148 ; Lawrence, Michael S. 457 ; Lazar, Alexander J. 458 ; Lazic, Ana Mijalkovic 243 ; Le, Xuan 459 ; Lee, Darlene 80 ; Lee, Donghoon 460 ; Lee, Hee Jin 396 ; Lee, Jeong-Yeon 461 ; Lee, Juhee 462 ; Lee, Ming Ta Michael 463 ; Lee-Six, Henry 66 ; Lehmann, Kjong-Van 410 ; Lehrach, Hans 464 ; Lenze, Dido 385 ; Leonard, Conrad R. 374 ; Leongamornlert, Daniel A. 465 ; Leshchiner, Ignaty 21 ; Letourneau, Louis 466 ; Letunic, Ivica 467 ; Levine, Douglas A. 468 ; Lewis, Lora 229 ; Ley, Tim 469 ; Li, Chang 378 ; Li, Constance H. 139 ; Li, Haiyan Irene 80 ; Li, Jun 73 ; Li, Lin 306 ; Li, Shantao 460 ; Li, Siliang 378 ; Li, Xiaobo 378 ; Li, Xiaotong 460 ; Li, Xinyue 306 ; Liang, Han 470 ; Liang, Sheng-Ben 196 ; Lichter, Peter 471 ; Lin, Pei 21 ; Lin, Ziao 472 ; Linehan, W. M. 473 ; Lingjærde, Ole Christian 474 ; Liu, Dongbing 378 ; Liu, Eric Minwei 475 ; Liu, Fei-Fei Fei 476 ; Liu, Fenglin 477 ; Liu, Jia 478 ; Liu, Xingmin 378 ; Livingstone, Julie 113 ; Livitz, Dimitri 21 ; Livni, Naomi 186 ; Lochovsky, Lucas 479 ; Loeffler, Markus 441 ; Long, Georgina V. 179 ; Lopez-Guillermo, Armando 480 ; Lou, Shaoke 444 ; Louis, David N. 144 ; Lovat, Laurence B. 420 ; Lu, Yiling 358 ; Lu, Yong-Jie 481 ; Lu, Youyong 482 ; Luchini, Claudio 136 ; Lungu, Ilinca 483 ; Luo, Xuemei 318 ; Luxton, Hayley J. 420 ; Lype, Lisa 484 ; López, Cristina 85 ; López-Otín, Carlos 485 ; Ma, Eric Z. 381 ; Ma, Yussanne 80 ; MacGrogan, Gaetan 486 ; MacRae, Shona 487 ; Madsen, Tobias 377 ; Maejima, Kazuhiro 47 ; Mafficini, Andrea 148 ; Maglinte, Dennis T. 488 ; Maitra, Arindam 145 ; Majumder, Partha P. 145 ; Malcovati, Luca 194 ; Malikic, Salem 264 ; Malleo, Giuseppe 88 ; Mann, Graham J. 489 ; Mantovani-Löffler, Luisa 490 ; Marchal, Kathleen 491 ; Marchegiani, Giovanni 88 ; Mardis, Elaine R. 492 ; Margolin, Adam A. 493 ; Marin, Maximillian G. 494 ; Markowski, Julia 388 ; Marks, Jeffrey 495 ; Marques-Bonet, Tomas 496 ; Marra, Marco A. 80 ; Marsden, Luke 320 ; Martens, John W. M. 295 ; Martin, Sancha 497 ; Martin-Subero, Jose I. 498 ; Maruvka, Yosef E. 499 ; Mashl, R. Jay 500 ; Massie, Charlie E. 267 ; Matthew, Thomas J. 494 ; Matthews, Lucy 149 ; Mayer, Erik 501 ; Mayes, Simon 502 ; Mayo, Michael 80 ; Mbabaali, Faridah 236 ; McCune, Karen 503 ; McDermott, Ultan 66 ; McGillivray, Patrick D. 48 ; McLellan, Michael D. 260 ; McPherson, John D. 504 ; McPherson, John R. 150 ; McPherson, Treasa A. 505 ; Meier, Samuel R. 21 ; Meng, Alice 506 ; Meng, Shaowu 108 ; Menzies, Andrew 66 ; Merrett, Neil D. 507 ; Merson, Sue 149 ; Meyerson, William 508 ; Mieczkowski, Piotr A. 509 ; Mihaiescu, George L. 84 ; Mijalkovic, Sanja 243 ; Mikkelsen, Tom 510 ; Milella, Michele 217 ; Mileshkin, Linda 81 ; Miller, Christopher A. 302 ; Miller, David K. 511 ; Miller, Jessica K. 236 ; Mills, Gordon B. 512 ; Milovanovic, Ana 20 ; Minner, Sarah 513 ; Miotto, Marco 88 ; Arnau, Gisela Mir 230 ; Mirabello, Lisa 202 ; Mitchell, Chris 81 ; Mitchell, Thomas J. 514 ; Miyoshi, Naoki 350 ; Mizuno, Shinichi 515 ; Molnár-Gábor, Fruzsina 516 ; Moore, Malcolm J. 255 ; Moore, Richard A. 80 ; Morganella, Sandro 66 ; Morris, Quaid D. 517 ; Morrison, Carl 518 ; Mose, Lisle E. 108 ; Moser, Catherine D. 317 ; Muiños, Ferran 254 ; Mularoni, Loris 254 ; Mungall, Andrew J. 80 ; Mungall, Karen 80 ; Musgrove, Elizabeth A. 107 ; Mustonen, Ville 519 ; Mutch, David 520 ; Muyas, Francesc 248 ; Muzny, Donna M. 229 ; Muñoz, Alfonso 116 ; Myers, Jerome 521 ; Myklebost, Ola 522 ; Möller, Peter 523 ; Nagae, Genta 68 ; Nagrial, Adnan M. 401 ; Nahal-Bose, Hardeep K. 84 ; Nakagama, Hitoshi 524 ; Nakamura, Hiromi 92 ; Nakamura, Toru 365 ; Nakano, Kaoru 47 ; Nandi, Tannistha 525 ; Nangalia, Jyoti 66 ; Nastic, Mia 243 ; Navarro, Arcadi 526 ; Neal, David E. 527 ; Nettekoven, Gerd 528 ; Newell, Felicity 374 ; Newhouse, Steven J. 116 ; Newton, Yulia 494 ; Ng, Alvin Wei Tian 529 ; Ng, Anthony 530 ; Nicholson, Jonathan 66 ; Nicol, David 186 ; Nie, Yongzhan 531 ; Nielsen, G. Petur 144 ; Nielsen, Morten Muhlig 377 ; Nik-Zainal, Serena 532 ; Noble, Michael S. 21 ; Nones, Katia 374 ; Northcott, Paul A. 533 ; Notta, Faiyaz 534 ; O’Connor, Brian D. 535 ; O’Donnell, Peter 536 ; O’Donovan, Maria 292 ; O’Meara, Sarah 66 ; O’Neill, Brian Patrick 537 ; O’Neill, J. Robert 538 ; Ocana, David 116 ; Ochoa, Angelica 67 ; Oesper, Layla 539 ; Ogden, Christopher 186 ; Ohdan, Hideki 72 ; Ohi, Kazuhiro 350 ; Ohno-Machado, Lucila 207 ; Oien, Karin A. 540 ; Ojesina, Akinyemi I. 541 ; Ojima, Hidenori 542 ; Okusaka, Takuji 543 ; Omberg, Larsson 544 ; Ong, Choon Kiat 545 ; Ott, German 546 ; Ouellette, B. F. Francis 547 ; P’ng, Christine 113 ; Paczkowska, Marta 113 ; Paiella, Salvatore 88 ; Pairojkul, Chawalit 548 ; Pajic, Marina 401 ; Pan-Hammarström, Qiang 549 ; Papaemmanuil, Elli 66 ; Papatheodorou, Irene 116 ; Paramasivam, Nagarajan 550 ; Park, Ji Wan 362 ; Park, Joong-Won 551 ; Park, Keunchil 552 ; Park, Kiejung 553 ; Parker, Joel S. 509 ; Parsons, Simon L. 554 ; Pass, Harvey 555 ; Pasternack, Danielle 236 ; Pastore, Alessandro 556 ; Patch, Ann-Marie 374 ; Pauporté, Iris 213 ; Pea, Antonio 88 ; Pedamallu, Chandra Sekhar 13 ; Pedersen, Jakob Skou 557 ; Pederzoli, Paolo 88 ; Peifer, Martin 234 ; Pennell, Nathan A. 558 ; Perou, Charles M. 559 ; Perry, Marc D. 560 ; Petersen, Gloria M. 561 ; Peto, Myron 89 ; Petrelli, Nicholas 562 ; Petryszak, Robert 116 ; Pfister, Stefan M. 563 ; Phillips, Mark 404 ; Pich, Oriol 254 ; Pickett, Hilda A. 455 ; Pihl, Todd D. 564 ; Pillay, Nischalan 565 ; Pinder, Sarah 566 ; Pinese, Mark 401 ; Pinho, Andreia V. 567 ; Pitkänen, Esa 278 ; Pivot, Xavier 568 ; Piñeiro-Yáñez, Elena 75 ; Planko, Laura 528 ; Plass, Christoph 313 ; Polak, Paz 569 ; Pons, Tirso 570 ; Popescu, Irinel 571 ; Potapova, Olga 572 ; Prasad, Aparna 573 ; Preston, Shaun R. 574 ; Prinz, Manuel 2 ; Pritchard, Antonia L. 272 ; Prokopec, Stephenie D. 113 ; Provenzano, Elena 575 ; Puente, Xose S. 576 ; Puig, Sonia 147 ; Pulido-Tamayo, Sergio 491 ; Pupo, Gulietta M. 577 ; Purdie, Colin A. 578 ; Quinn, Michael C. 374 ; Rabionet, Raquel 579 ; Rader, Janet S. 580 ; Radlwimmer, Bernhard 379 ; Radovic, Petar 243 ; Raeder, Benjamin 278 ; Raine, Keiran M. 66 ; Ramakrishna, Manasa 66 ; Ramakrishnan, Kamna 66 ; Ramalingam, Suresh 581 ; Raphael, Benjamin J. 582 ; Rathmell, W. Kimryn 583 ; Rausch, Tobias 278 ; Reifenberger, Guido 584 ; Reimand, Jüri 139 ; Reis-Filho, Jorge 316 ; Reuter, Victor 316 ; Reyes-Salazar, Iker 300 ; Reyna, Matthew A. 582 ; Reynolds, Sheila M. 484 ; Rheinbay, Esther 445 ; Riazalhosseini, Yasser 454 ; Richardson, Andrea L. 284 ; Richter, Julia 585 ; Ringel, Matthew 586 ; Ringnér, Markus 151 ; Rino, Yasushi 587 ; Roach, Jeffrey 588 ; Roberts, Lewis R. 317 ; Robertson, A. Gordon 80 ; Robertson, Alan J. 86 ; Rodriguez, Javier Bartolomé 20 ; Rodríguez-González, F. Germán 589 ; Roehrl, Michael H. A. 590 ; Rohde, Marius 591 ; Rokutan, Hirofumi 419 ; Romieu, Gilles 592 ; Rooman, Ilse 401 ; Roques, Tom 593 ; Rosebrock, Daniel 21 ; Rosenberg, Mara 346 ; Rosenstiel, Philip C. 594 ; Rosenwald, Andreas 595 ; Rowe, Edward W. 596 ; Royo, Romina 20 ; Rozen, Steven G. 597 ; Rubanova, Yulia 598 ; Rubin, Mark A. 599 ; Rubio-Perez, Carlota 600 ; Rudneva, Vasilisa A. 278 ; Rusev, Borislav C. 148 ; Ruzzenente, Andrea 601 ; Rätsch, Gunnar 602 ; Sabarinathan, Radhakrishnan 603 ; Sabelnykova, Veronica Y. 113 ; Sadeghi, Sara 80 ; Sahinalp, S. Cenk 604 ; Saini, Natalie 28 ; Saito-Adachi, Mihoko 419 ; Saksena, Gordon 21 ; Salcedo, Adriana 113 ; Salgado, Roberto 605 ; Salichos, Leonidas 444 ; Sallari, Richard 21 ; Saller, Charles 606 ; Salvia, Roberto 88 ; Sam, Michelle 236 ; Samra, Jaswinder S. 607 ; Sanchez-Vega, Francisco 206 ; Sander, Chris 608 ; Sanders, Grant 108 ; Sarin, Rajiv 609 ; Sarrafi, Iman 264 ; Sasaki-Oku, Aya 47 ; Sauer, Torill 474 ; Sauter, Guido 513 ; Saw, Robyn P. M. 179 ; Scardoni, Maria 136 ; Scarlett, Christopher J. 610 ; Scarpa, Aldo 148 ; Scelo, Ghislaine 163 ; Schadendorf, Dirk 611 ; Schein, Jacqueline E. 80 ; Schilhabel, Markus B. 594 ; Schlomm, Thorsten 612 ; Schmidt, Heather K. 302 ; Schramm, Sarah-Jane 577 ; Schreiber, Stefan 613 ; Schultz, Nikolaus 95 ; Schwarz, Roland F. 614 ; Scolyer, Richard A. 615 ; Scott, David 406 ; Seethala, Raja 616 ; Segre, Ayellet V. 617 ; Selander, Iris 505 ; Semple, Colin A. 412 ; Senbabaoglu, Yasin 556 ; Sengupta, Subhajit 618 ; Sereni, Elisabetta 88 ; Serra, Stefano 619 ; Sgroi, Dennis C. 144 ; Shah, Nimish C. 380 ; Shahabi, Sagedeh 196 ; Shang, Catherine A. 291 ; Shang, Ping 179 ; Shapira, Ofer 53 ; Shelton, Troy 235 ; Shen, Ciyue 620 ; Shen, Hui 621 ; Shepherd, Rebecca 66 ; Shi, Ruian 622 ; Shi, Yan 108 ; Shiah, Yu-Jia 113 ; Shibata, Tatsuhiro 623 ; Shih, Juliann 178 ; Shimizu, Eigo 350 ; Shimizu, Kiyo 624 ; Shin, Seung Jun 625 ; Shiraishi, Yuichi 350 ; Shmaya, Tal 626 ; Shmulevich, Ilya 484 ; Shorser, Solomon I. 113 ; Short, Charles 116 ; Shrestha, Raunak 222 ; Shringarpure, Suyash S. 627 ; Shriver, Craig 628 ; Shuai, Shimin 103 ; Siebert, Reiner 629 ; Sieuwerts, Anieta M. 295 ; Signoretti, Sabina 630 ; Sikora, Katarzyna O. 148 ; Simbolo, Michele 111 ; Simon, Ronald 513 ; Simons, Janae V. 108 ; Simpson, Jared T. 631 ; Simpson, Peter T. 449 ; Singer, Samuel 632 ; Sinnott-Armstrong, Nasa 633 ; Sipahimalani, Payal 80 ; Skelly, Tara J. 634 ; Smid, Marcel 295 ; Smith, Jaclyn 635 ; Smith-McCune, Karen 503 ; Socci, Nicholas D. 556 ; Sofia, Heidi J. 332 ; Soloway, Matthew G. 108 ; Song, Lei 202 ; Sood, Anil K. 636 ; Sothi, Sharmila 637 ; Sotiriou, Christos 207 ; Soulette, Cameron M. 494 ; Span, Paul N. 638 ; Spellman, Paul T. 89 ; Sperandio, Nicola 148 ; Spillane, Andrew J. 179 ; Spiro, Oliver 21 ; Spring, Jonathan 639 ; Staaf, Johan 151 ; Stadler, Peter F. 134 ; Staib, Peter 640 ; Stark, Stefan G. 641 ; Stebbings, Lucy 66 ; Stefánsson, Ólafur Andri 642 ; Stegle, Oliver 643 ; Stein, Lincoln D. 103 ; Stenhouse, Alasdair 644 ; Stilgenbauer, Stephan 645 ; Stobbe, Miranda D. 127 ; Stratton, Michael R. 66 ; Stretch, Jonathan R. 179 ; Struck, Adam J. 493 ; Stuart, Joshua M. 646 ; Stunnenberg, Henk G. 647 ; Su, Hong 378 ; Su, Xiaoping 167 ; Sun, Ren X. 113 ; Sungalee, Stephanie 278 ; Susak, Hana 266 ; Suzuki, Akihiro 648 ; Sweep, Fred 649 ; Szczepanowski, Monika 434 ; Sültmann, Holger 650 ; Yugawa, Takashi 624 ; Tam, Angela 80 ; Tamborero, David 254 ; Tan, Benita Kiat Tee 651 ; Tan, Donghui 509 ; Tan, Patrick 652 ; Tanaka, Hiroko 350 ; Taniguchi, Hirokazu 653 ; Tanskanen, Tomas J. 654 ; Tarabichi, Maxime 655 ; Tarnuzzer, Roy 185 ; Tarpey, Patrick 656 ; Taschuk, Morgan L. 318 ; Tatsuno, Kenji 68 ; Tavaré, Simon 657 ; Taylor, Darrin F. 86 ; Taylor-Weiner, Amaro 21 ; Teague, Jon W. 66 ; Teh, Bin Tean 658 ; Tembe, Varsha 577 ; Temes, Javier 659 ; Thai, Kevin 84 ; Thayer, Sarah P. 373 ; Thiessen, Nina 80 ; Thomas, Gilles 660 ; Thomas, Sarah 186 ; Thompson, Alan 186 ; Thompson, Alastair M. 644 ; Thompson, John F. F. 179 ; Thompson, R. Houston 661 ; Thorne, Heather 81 ; Thorne, Leigh B. 147 ; Thorogood, Adrian 404 ; Tiao, Grace 21 ; Tijanic, Nebojsa 243 ; Timms, Lee E. 236 ; Tirabosco, Roberto 662 ; Tojo, Marta 663 ; Tommasi, Stefania 664 ; Toon, Christopher W. 401 ; Toprak, Umut H. 665 ; Tortora, Giampaolo 666 ; Tost, Jörg 667 ; Totoki, Yasushi 92 ; Townend, David 668 ; Traficante, Nadia 81 ; Treilleux, Isabelle 669 ; Trotta, Jean-Rémi 670 ; Trümper, Lorenz H. P. 443 ; Tsao, Ming 671 ; Tsunoda, Tatsuhiko 672 ; Tucker, Olga 673 ; Turkington, Richard 674 ; Turner, Daniel J. 502 ; Tutt, Andrew 284 ; Ueno, Masaki 352 ; Ueno, Naoto T. 675 ; Umbricht, Christopher 676 ; Umer, Husen M. 677 ; Underwood, Timothy J. 678 ; Urban, Lara 187 ; Urushidate, Tomoko 653 ; Ushiku, Tetsuo 301 ; Uusküla-Reimand, Liis 679 ; Valencia, Alfonso 57 ; Van Den Berg, David J. 135 ; Van Laere, Steven 263 ; Van Loo, Peter 247 ; Van Meir, Erwin G. 680 ; Van den Eynden, Gert G. 263 ; Van der Kwast, Theodorus 681 ; Vasudev, Naveen 110 ; Vazquez, Miguel 682 ; Vedururu, Ravikiran 230 ; Veluvolu, Umadevi 509 ; Vembu, Shankar 683 ; Verbeke, Lieven P. C. 684 ; Vermeulen, Peter 263 ; Verrill, Clare 685 ; Viari, Alain 148 ; Vicente, David 20 ; Vicentini, Caterina 148 ; VijayRaghavan, K. 337 ; Viksna, Juris 686 ; Vilain, Ricardo E. 687 ; Vincent-Salomon, Anne 688 ; Visakorpi, Tapio 159 ; Voet, Douglas 21 ; Vyas, Paresh 689 ; Vázquez-García, Ignacio 690 ; Waddell, Nick M. 691 ; Wadelius, Claes 692 ; Wadi, Lina 113 ; Wagener, Rabea 85 ; Wang, Jian 306 ; Wang, Jiayin 693 ; Wang, Linghua 229 ; Wang, Qi 438 ; Wang, Wenyi 73 ; Wang, Yumeng 694 ; Wang, Zhining 185 ; Waring, Paul M. 548 ; Warnatz, Hans-Jörg 464 ; Warrell, Jonathan 444 ; Warren, Anne Y. 695 ; Waszak, Sebastian M. 278 ; Wedge, David C. 696 ; Weichenhan, Dieter 313 ; Weinberger, Paul 697 ; Weinstein, John N. 358 ; Weisenberger, Daniel J. 135 ; Welch, Ian 698 ; Wendl, Michael C. 699 ; Werner, Johannes 700 ; Whalley, Justin P. 701 ; Wheeler, David A. 702 ; Whitaker, Hayley C. 420 ; Wigle, Dennis 703 ; Wilkerson, Matthew D. 509 ; Williams, Ashley 207 ; Wilmott, James S. 179 ; Wilson, Gavin W. 704 ; Wilson, Julie M. 120 ; Wilson, Richard K. 705 ; Winterhoff, Boris 706 ; Wintersinger, Jeffrey A. 707 ; Wiznerowicz, Maciej 708 ; Wolf, Stephan 709 ; Wong, Bernice H. 710 ; Wong, Tina 711 ; Wong, Winghing 712 ; Woo, Youngchoon 212 ; Wood, Scott 374 ; Wouters, Bradly G. 713 ; Wright, Adam J. 113 ; Wright, Derek W. 714 ; Wright, Mark H. 627 ; Wu, Chin-Lee 144 ; Wu, Dai-Ying 715 ; Wu, Guanming 716 ; Wu, Jianmin 401 ; Wu, Kui 378 ; Wu, Yang 150 ; Wu, Zhenggang 381 ; Xi, Liu 229 ; Xia, Tian 717 ; Xiang, Qian 84 ; Xiao, Xiao 718 ; Xing, Rui 719 ; Xiong, Heng 378 ; Xu, Qinying 374 ; Xu, Yanxun 720 ; Xue, Hong 381 ; Yachida, Shinichi 721 ; Yakneen, Sergei 722 ; Yamaguchi, Rui 350 ; Yamaguchi, Takafumi N. 113 ; Yamamoto, Masakazu 94 ; Yamamoto, Shogo 68 ; Yamaue, Hiroki 352 ; Yang, Fan 622 ; Yang, Huanming 306 ; Yang, Jean Y. 723 ; Yang, Liming 185 ; Yang, Shanlin 261 ; Yang, Tsun-Po 234 ; Yang, Yang 343 ; Yaspo, Marie-Laure 464 ; Yates, Lucy 66 ; Yau, Christina 128 ; Ye, Chen 378 ; Ye, Kai 724 ; Yellapantula, Venkata D. 725 ; Yoon, Christopher J. 211 ; Yousif, Fouad 113 ; Yu, Jun 726 ; Yu, Kaixian 727 ; Yu, Willie 728 ; Yu, Yingyan 729 ; Yuan, Ke 730 ; Yuan, Yuan 73 ; Yuen, Denis 113 ; Yung, Christina K. 84 ; Zaikova, Olga 731 ; Zapatka, Marc 379 ; Zenklusen, Jean C. 185 ; Zenz, Thorsten 732 ; Zeps, Nikolajs 733 ; Zhang, Fan 734 ; Zhang, Hailei 21 ; Zhang, Hongwei 735 ; Zhang, Hongxin 95 ; Zhang, Jiashan 185 ; Zhang, Jing 460 ; Zhang, Junjun 84 ; Zhang, Xiuqing 306 ; Zhang, Xuanping 736 ; Zhang, Yan 737 ; Zhang, Zemin 356 ; Zhao, Zhongming 738 ; Zheng, Liangtao 734 ; Zheng, Xiuqing 734 ; Zhou, Wanding 621 ; Zhou, Yong 306 ; Zhu, Bin 202 ; Zhu, Hongtu 739 ; Zhu, Jingchun 231 ; Zhu, Shida 378 ; Zou, Lihua 740 ; Zou, Xueqing 66 ; deFazio, Anna 741 ; van As, Nicholas 186 ; van Deurzen, Carolien H. M. 742 ; van de Vijver, Marc J. 548 ; van’t Veer, L. 743 ; von Mering, Christian 744 

 German Cancer Research Center (DKFZ), Division of Applied Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Heidelberg University, Faculty of Biosciences, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373) 
 German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
 German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant, Department for Bioinformatics and Functional Genomics, Heidelberg, Germany (GRID:grid.7497.d) 
 German Cancer Consortium (DKTK), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany (GRID:grid.461742.2) (ISNI:0000 0000 8855 0365); German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
 Heidelberg University, Faculty of Biosciences, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); German Cancer Research Center (DKFZ) and BioQuant, Division of Chromatin Networks, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
 Harvard Medical School, Department of Biomedical Informatics, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Centre for Molecular Science Informatics, University of Cambridge, Department of Chemistry, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); Ludwig Center at Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
 Peking University, School of Mathematical Sciences and Center for Statistical Science, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
 Harvard Medical School, Department of Biomedical Informatics, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Ludwig Center at Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
 German Cancer Research Center (DKFZ), Bioinformatics and Omics Data Analytics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
10  University of Texas MD Anderson Cancer Center, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
11  Universidade de Santiago de Compostela, Department of Zoology, Genetics and Physical Anthropology, Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645); Universidade de Santiago de Compostela, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645); Universidade de Vigo, The Biomedical Research Centre (CINBIO), Vigo, Spain (GRID:grid.6312.6) (ISNI:0000 0001 2097 6738) 
12  University of Cambridge, Transmissible Cancer Group, Department of Veterinary Medicine, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
13  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Dana-Farber Cancer Institute, Department of Medical Oncology, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910); Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
14  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Toronto, Department of Medical Biophysics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); University of Toronto, Department of Pharmacology, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); University of California Los Angeles, Los Angeles, USA (GRID:grid.19006.3e) (ISNI:0000 0000 9632 6718) 
15  Peter MacCallum Cancer Centre, Melbourne, Australia (GRID:grid.1055.1) (ISNI:0000000403978434); University of Melbourne, Sir Peter MacCallum Department of Oncology, Melbourne, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X) 
16  German Cancer Research Center (DKFZ), Division of Applied Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); German Cancer Consortium (DKTK), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany (GRID:grid.461742.2) (ISNI:0000 0000 8855 0365) 
17  Johns Hopkins School of Medicine, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311) 
18  Wellcome Genome Campus, Wellcome Sanger Institute, Hinxton, UK (GRID:grid.52788.30) (ISNI:0000 0004 0427 7672); University of Cambridge, Department of Haematology, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
19  Microbiology and Immunology, University of Ottawa Faculty of Medicine, Department of Biochemistry, Ottawa, Canada (GRID:grid.28046.38) (ISNI:0000 0001 2182 2255) 
20  Barcelona Supercomputing Center (BSC), Barcelona, Spain (GRID:grid.10097.3f) (ISNI:0000 0004 0387 1602) 
21  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623) 
22  University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); University of Cambridge, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
23  Quantitative Genomics Laboratories (qGenomics), Barcelona, Spain (GRID:grid.5335.0); The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299) 
24  German Cancer Research Center (DKFZ), Division of Applied Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
25  Barcelona Supercomputing Center (BSC), Barcelona, Spain (GRID:grid.10097.3f) (ISNI:0000 0004 0387 1602); The University of Queensland, Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, St Lucia, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537) 
26  Bar-Ilan University, The Azrieli Faculty of Medicine, Safed, Israel (GRID:grid.22098.31) (ISNI:0000 0004 1937 0503) 
27  Yale University, Department of Computer Science, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710); Yale University, Department of Molecular Biophysics and Biochemistry, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710); Yale University, Program in Computational Biology and Bioinformatics, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710) 
28  National Institute of Environmental Health Sciences (NIEHS), Genome Integrity and Structural Biology Laboratory, Durham, USA (GRID:grid.280664.e) (ISNI:0000 0001 2110 5790) 
29  University of California, Santa Cruz, Biomolecular Engineering Department, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
30  Brandeis University, Waltham, USA (GRID:grid.253264.4) (ISNI:0000 0004 1936 9473) 
31  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Massachusetts General Hospital Center for Cancer Research, Charlestown, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
32  New York Genome Center, New York, USA (GRID:grid.429884.b) (ISNI:0000 0004 1791 0895); Weill Cornell Medicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
33  Hopp Children’s Cancer Center (KiTZ), Heidelberg, Germany (GRID:grid.510964.f); Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
34  German Cancer Research Center (DKFZ), Division of Applied Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Wellcome Genome Campus, Wellcome Sanger Institute, Hinxton, UK (GRID:grid.52788.30) (ISNI:0000 0004 0427 7672); Korea Advanced Institute of Science and Technology, Daejeon, South Korea (GRID:grid.37172.30) (ISNI:0000 0001 2292 0500) 
35  Skolkovo Institute of Science and Technology, Moscow, Russia (GRID:grid.454320.4) (ISNI:0000 0004 0555 3608); A.A.Kharkevich Institute of Information Transmission Problems, Moscow, Russia (GRID:grid.435025.5) (ISNI:0000 0004 0619 6198); Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia (GRID:grid.465331.6) 
36  National Institute of Environmental Health Sciences (NIEHS), Integrative Bioinformatics Support Group, Durham, USA (GRID:grid.280664.e) (ISNI:0000 0001 2110 5790) 
37  Seoul National University Hospital, Center For Medical Innovation, Seoul, South Korea (GRID:grid.412484.f) (ISNI:0000 0001 0302 820X); Seoul National University Hospital, Department of Internal Medicine, Seoul, South Korea (GRID:grid.412484.f) (ISNI:0000 0001 0302 820X) 
38  European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, European Molecular Biology Laboratory, Cambridge, UK (GRID:grid.225360.0) (ISNI:0000 0000 9709 7726); European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany (GRID:grid.4709.a) (ISNI:0000 0004 0495 846X) 
39  Boston Children’s Hospital and Harvard Medical School, Division of Genetics and Genomics, Boston, USA (GRID:grid.2515.3) (ISNI:0000 0004 0378 8438) 
40  National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany (GRID:grid.461742.2) (ISNI:0000 0000 8855 0365); German Cancer Research Center (DKFZ) and BioQuant, Division of Chromatin Networks, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
41  Wellcome Genome Campus, Wellcome Sanger Institute, Hinxton, UK (GRID:grid.52788.30) (ISNI:0000 0004 0427 7672) 
42  University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); University of Cambridge, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); University of St Andrews, St Andrews, School of Medicine/School of Mathematics and Statistics, Fife, UK (GRID:grid.11914.3c) (ISNI:0000 0001 0721 1626) 
43  University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
44  Weill Cornell Medicine, Department of Physiology and Biophysics, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Weill Cornell Medicine, Englander Institute for Precision Medicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Weill Cornell Medicine, Institute for Computational Biomedicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
45  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Dana-Farber Cancer Institute, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910); University Hospital and University of Bern, Department of Medical Oncology, Inselspital, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); The University of Melbourne, Department of Pathology, Melbourne, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X) 
46  The University of Tokyo, The Institute of Medical Science, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X) 
47  RIKEN Center for Integrative Medical Sciences, Yokohama, Japan (GRID:grid.509459.4) (ISNI:0000 0004 0472 0267) 
48  Yale University, Department of Molecular Biophysics and Biochemistry, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710) 
49  The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); University of Tübingen, Institute of Medical Genetics and Applied Genomics, Tübingen, Germany (GRID:grid.10392.39) (ISNI:0000 0001 2190 1447); Universitat Pompeu Fabra (UPF), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676) 
50  QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Australia (GRID:grid.1049.c) (ISNI:0000 0001 2294 1395); University of Queensland, St Lucia, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537) 
51  German Cancer Research Center (DKFZ) and BioQuant, Division of Chromatin Networks, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
52  Washington State University, School of Molecular Biosciences and Center for Reproductive Biology, Pullman, USA (GRID:grid.30064.31) (ISNI:0000 0001 2157 6568) 
53  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Dana-Farber Cancer Institute, Department of Cancer Biology, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910) 
54  Beth Israel Deaconess Medical Center, Cancer Research Institute, Boston, USA (GRID:grid.239395.7) (ISNI:0000 0000 9011 8547) 
55  University of Melbourne, Sir Peter MacCallum Department of Oncology, Melbourne, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X); Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia (GRID:grid.1055.1) (ISNI:0000000403978434) 
56  University of Copenhagen, Finsen Laboratory and Biotech Research & Innovation Centre (BRIC), Copenhagen, Denmark (GRID:grid.5254.6) (ISNI:0000 0001 0674 042X) 
57  Barcelona Supercomputing Center (BSC), Barcelona, Spain (GRID:grid.10097.3f) (ISNI:0000 0004 0387 1602); Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain (GRID:grid.425902.8) (ISNI:0000 0000 9601 989X) 
58  National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany (GRID:grid.461742.2) (ISNI:0000 0000 8855 0365); Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Dana-Farber Cancer Institute, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910) 
59  European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany (GRID:grid.4709.a) (ISNI:0000 0004 0495 846X); University of Copenhagen, Finsen Laboratory and Biotech Research & Innovation Centre (BRIC), Copenhagen, Denmark (GRID:grid.5254.6) (ISNI:0000 0001 0674 042X); Charité Universitätsmedizin Berlin, Department of Urology, Berlin, Germany (GRID:grid.6363.0) (ISNI:0000 0001 2218 4662) 
60  The University of Chicago, Ben May Department for Cancer Research, Department of Human Genetics, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822) 
61  New York Genome Center, New York, USA (GRID:grid.429884.b) (ISNI:0000 0004 1791 0895); Weill Cornell Medicine, Tri-institutional PhD program of computational biology and medicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
62  Seoul National University Hospital, Department of Internal Medicine, Seoul, South Korea (GRID:grid.412484.f) (ISNI:0000 0001 0302 820X) 
63  Universidade de Santiago de Compostela, Department of Zoology, Genetics and Physical Anthropology, Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645); Universidade de Santiago de Compostela, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645); Universidade de Vigo, The Biomedical Research Centre (CINBIO), Vigo, Spain (GRID:grid.6312.6) (ISNI:0000 0001 2097 6738); Wellcome Genome Campus, Wellcome Sanger Institute, Hinxton, UK (GRID:grid.52788.30) (ISNI:0000 0004 0427 7672) 
64  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Dana-Farber Cancer Institute, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910) 
65  Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071) 
66  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382) 
67  Memorial Sloan Kettering Cancer Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
68  University of Tokyo, Genome Science Division, Research Center for Advanced Science and Technology, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X) 
69  University of Chicago, Department of Surgery, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822) 
70  Keimyung University Dongsan Medical Center, Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, School of Medicine, Daegu, South Korea (GRID:grid.414067.0) (ISNI:0000 0004 0647 8419) 
71  Gachon University, Department of Oncology, Gil Medical Center, Incheon, South Korea (GRID:grid.256155.0) (ISNI:0000 0004 0647 2973) 
72  Hiroshima University, Hiroshima, Japan (GRID:grid.257022.0) (ISNI:0000 0000 8711 3200) 
73  The University of Texas MD Anderson Cancer Center, Department of Bioinformatics and Computational Biology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
74  King Faisal Specialist Hospital and Research Centre, Al Maather, Riyadh, Saudi Arabia (GRID:grid.415310.2) (ISNI:0000 0001 2191 4301) 
75  Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain (GRID:grid.7719.8) (ISNI:0000 0000 8700 1153) 
76  University Medical Center Hamburg, Bioinformatics Core Facility, Hamburg, Germany (GRID:grid.13648.38) (ISNI:0000 0001 2180 3484); Leibniz Institute for Experimental Virology, Heinrich Pette Institute, Hamburg, Germany (GRID:grid.418481.0) (ISNI:0000 0001 0665 103X) 
77  Ontario Institute for Cancer Research, Ontario Tumour Bank, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
78  The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); National Cancer Institute, Laboratory of Pathology, Center for Cancer Research, Bethesda, USA (GRID:grid.48336.3a) (ISNI:0000 0004 1936 8075) 
79  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); University of California San Diego, Department of Cellular and Molecular Medicine and Department of Bioengineering, La Jolla, USA (GRID:grid.266100.3) (ISNI:0000 0001 2107 4242); UC San Diego Moores Cancer Center, San Diego, USA (GRID:grid.516081.b) (ISNI:0000 0000 9217 9714) 
80  Canada’s Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada (GRID:grid.434706.2) (ISNI:0000 0004 0410 5424) 
81  University of Melbourne, Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X) 
82  Royal National Orthopaedic Hospital - Bolsover, London, UK (GRID:grid.416177.2) (ISNI:0000 0004 0417 7890) 
83  The University of Texas MD Anderson Cancer Center, Department of Genomic Medicine, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); Baylor College of Medicine, Quantitative and Computational Biosciences Graduate Program, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X); The Jackson Laboratory for Genomic Medicine, Farmington, USA (GRID:grid.249880.f) (ISNI:0000 0004 0374 0039) 
84  Ontario Institute for Cancer Research, Genome Informatics Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
85  Christian-Albrechts-University, Institute of Human Genetics, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986); Ulm University and Ulm University Medical Center, Institute of Human Genetics, Ulm, Germany (GRID:grid.410712.1) (ISNI:0000 0004 0473 882X) 
86  University of Queensland, St. Lucia, Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537) 
87  Salford Royal NHS Foundation Trust, Salford, UK (GRID:grid.412346.6) (ISNI:0000 0001 0237 2025) 
88  University and Hospital Trust of Verona, Department of Surgery, Pancreas Institute, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
89  Oregon Health and Science University, Molecular and Medical Genetics, OHSU Knight Cancer Institute, Portland, USA (GRID:grid.5288.7) (ISNI:0000 0000 9758 5690) 
90  BC Cancer Research Centre, Department of Molecular Oncology, Vancouver, Canada (GRID:grid.248762.d) (ISNI:0000 0001 0702 3000) 
91  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); University College London, London, UK (GRID:grid.83440.3b) (ISNI:0000000121901201) 
92  National Cancer Center Research Institute, National Cancer Center, Division of Cancer Genomics, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385) 
93  DLR Project Management Agency, Bonn, Germany (GRID:grid.272242.3) 
94  Tokyo Women’s Medical University, Tokyo, Japan (GRID:grid.410818.4) (ISNI:0000 0001 0720 6587) 
95  Memorial Sloan Kettering Cancer Center, Center for Molecular Oncology, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
96  Los Alamos National Laboratory, Los Alamos, USA (GRID:grid.148313.c) (ISNI:0000 0004 0428 3079) 
97  University Health Network, Toronto General Hospital, Department of Pathology, Toronto, Canada (GRID:grid.417184.f) (ISNI:0000 0001 0661 1177); Nottingham University Hospitals NHS Trust, Nottingham, UK (GRID:grid.240404.6) (ISNI:0000 0001 0440 1889) 
98  German Cancer Research Center (DKFZ), Epigenomics and Cancer Risk Factors, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
99  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Toronto, Department of Molecular Genetics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); Vector Institute, Toronto, Canada (GRID:grid.494618.6) 
100  Ulm University and Ulm University Medical Center, Institute of Human Genetics, Ulm, Germany (GRID:grid.410712.1) (ISNI:0000 0004 0473 882X); Christian-Albrechts-University, Hematopathology Section, Institute of Pathology, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986) 
101  University of North Carolina at Chapel Hill, Department of Pathology and Laboratory Medicine, School of Medicine, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
102  Oslo University Hospital, The Norwegian Radium Hospital, Department of Cancer Genetics, Institute for Cancer Research, Oslo, Norway (GRID:grid.55325.34) (ISNI:0000 0004 0389 8485) 
103  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Toronto, Department of Molecular Genetics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
104  University of Barcelona, Pathology, Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (GRID:grid.5841.8) (ISNI:0000 0004 1937 0247) 
105  University of Toronto, Department of Molecular Genetics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
106  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Washington University School of Medicine, Alvin J. Siteman Cancer Center, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
107  University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X) 
108  University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
109  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, USA (GRID:grid.511177.4); Harvard Medical School, Department of Pediatrics, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
110  University of Leeds, St. James’s University Hospital, Leeds Institute of Medical Research @ St. James’s, Leeds, UK (GRID:grid.443984.6) (ISNI:0000 0000 8813 7132) 
111  University and Hospital Trust of Verona, Department of Pathology and Diagnostics, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
112  Princess Alexandra Hospital, Department of Surgery, Brisbane, Australia (GRID:grid.412744.0) (ISNI:0000 0004 0380 2017); University of Queensland, Surgical Oncology Group, Diamantina Institute, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537) 
113  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
114  Case Western Reserve University School of Medicine, Department of Population and Quantitative Health Sciences, Cleveland, USA (GRID:grid.67105.35) (ISNI:0000 0001 2164 3847); University Hospitals Cleveland Medical Center, Research Health Analytics and Informatics, Cleveland, USA (GRID:grid.443867.a) (ISNI:0000 0000 9149 4843) 
115  Gloucester Royal Hospital, Gloucester, UK (GRID:grid.413144.7) (ISNI:0000 0001 0489 6543) 
116  European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Cambridge, UK (GRID:grid.225360.0) (ISNI:0000 0000 9709 7726) 
117  Ontario Institute for Cancer Research, Ontario Tumour Bank, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
118  University of Calgary, Arnie Charbonneau Cancer Institute, Calgary, Canada (GRID:grid.22072.35) (ISNI:0000 0004 1936 7697); University of Calgary, Departments of Surgery and Oncology, Calgary, Canada (GRID:grid.22072.35) (ISNI:0000 0004 1936 7697) 
119  Oslo University Hospital, The Norwegian Radium Hospital, Department of Pathology, Oslo, Norway (GRID:grid.55325.34) (ISNI:0000 0004 0389 8485) 
120  Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
121  Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University School of Medicine, Department of Oncology, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311); University Hospital Southampton NHS Foundation Trust, Southampton, UK (GRID:grid.430506.4) (ISNI:0000 0004 0465 4079) 
122  Royal Stoke University Hospital, Stoke-on-Trent, UK (GRID:grid.439344.d) (ISNI:0000 0004 0641 6760) 
123  Ontario Institute for Cancer Research, Genome Sequence Informatics, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); Human Longevity Inc, San Diego, USA (GRID:grid.459583.6) (ISNI:0000 0004 4652 6825) 
124  La Trobe University, Olivia Newton-John Cancer Research Institute, Heidelberg, Australia (GRID:grid.1018.8) (ISNI:0000 0001 2342 0938) 
125  Chinese Academy of Sciences, Computer Network Information Center, Beijing, China (GRID:grid.9227.e) (ISNI:0000000119573309) 
126  Genome Canada, Ottawa, Canada (GRID:grid.440163.4) (ISNI:0000 0001 0352 8618) 
127  Barcelona Institute of Science and Technology (BIST), CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); Universitat Pompeu Fabra (UPF), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676) 
128  Buck Institute for Research on Aging, Novato, USA (GRID:grid.272799.0) (ISNI:0000 0000 8687 5377) 
129  Duke University Medical Center, Durham, USA (GRID:grid.189509.c) (ISNI:0000000100241216) 
130  Hannover Medical School, Department of Human Genetics, Hannover, Germany (GRID:grid.10423.34) (ISNI:0000 0000 9529 9877) 
131  University of California San Diego, Department of Cellular and Molecular Medicine and Department of Bioengineering, La Jolla, USA (GRID:grid.266100.3) (ISNI:0000 0001 2107 4242); UC San Diego Moores Cancer Center, San Diego, USA (GRID:grid.516081.b) (ISNI:0000 0000 9217 9714) 
132  Cedars-Sinai Medical Center, Center for Bioinformatics and Functional Genomics, Los Angeles, USA (GRID:grid.50956.3f) (ISNI:0000 0001 2152 9905); Cedars-Sinai Medical Center, Department of Biomedical Sciences, Los Angeles, USA (GRID:grid.50956.3f) (ISNI:0000 0001 2152 9905); The Hebrew University Faculty of Medicine, Jerusalem, Israel (GRID:grid.9619.7) (ISNI:0000 0004 1937 0538) 
133  Queen Mary University of London, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, London, UK (GRID:grid.4868.2) (ISNI:0000 0001 2171 1133) 
134  University of Leipzig, Department of Computer Science, Bioinformatics Group, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786); University of Leipzig, Interdisciplinary Center for Bioinformatics, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786); University of Leipzig, Transcriptome Bioinformatics, LIFE Research Center for Civilization Diseases, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786) 
135  University of Southern California, USC Norris Comprehensive Cancer Center, Los Angeles, USA (GRID:grid.42505.36) (ISNI:0000 0001 2156 6853) 
136  University and Hospital Trust of Verona, Department of Diagnostics and Public Health, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
137  Aarhus University, Department of Mathematics, Aarhus, Denmark (GRID:grid.7048.b) (ISNI:0000 0001 1956 2722); Aarhus University Hospital, Department of Molecular Medicine (MOMA), Aarhus N, Denmark (GRID:grid.154185.c) (ISNI:0000 0004 0512 597X) 
138  Instituto Carlos Slim de la Salud, Mexico City, Mexico (GRID:grid.154185.c) 
139  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Toronto, Department of Medical Biophysics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
140  University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X); University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432); University of New South Wales (UNSW Sydney), South Western Sydney Clinical School, Faculty of Medicine, Liverpool, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432); Glasgow Royal Infirmary, West of Scotland Pancreatic Unit, Glasgow, UK (GRID:grid.411714.6) (ISNI:0000 0000 9825 7840) 
141  Berlin Institute of Health and Charitè - Universitätsmedizin Berlin, Center for Digital Health, Berlin, Germany (GRID:grid.484013.a) (ISNI:0000 0004 6879 971X); German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
142  Duke University Medical Center, The Preston Robert Tisch Brain Tumor Center, Durham, USA (GRID:grid.189509.c) (ISNI:0000000100241216) 
143  University of Leipzig, Department of Computer Science, Bioinformatics Group, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786); University of Leipzig, Interdisciplinary Center for Bioinformatics, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786) 
144  Massachusetts General Hospital, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
145  National Institute of Biomedical Genomics, Kalyani, India (GRID:grid.410872.8) (ISNI:0000 0004 1774 5690) 
146  Oslo University Hospital, The Norwegian Radium Hospital, Department of Pathology, Oslo, Norway (GRID:grid.55325.34) (ISNI:0000 0004 0389 8485); University of Oslo, Institute of Clinical Medicine and Institute of Oral Biology, Oslo, Norway (GRID:grid.5510.1) (ISNI:0000 0004 1936 8921) 
147  University of North Carolina at Chapel Hill, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
148  University and Hospital Trust of Verona, ARC-Net Centre for Applied Research on Cancer, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
149  The Institute of Cancer Research, London, UK (GRID:grid.18886.3f) 
150  Duke-NUS Medical School, Centre for Computational Biology, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924); Duke-NUS Medical School, Programme in Cancer and Stem Cell Biology, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924) 
151  Lund University, Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund, Sweden (GRID:grid.4514.4) (ISNI:0000 0001 0930 2361) 
152  Heinrich-Heine-University, Department of Pediatric Oncology, Hematology and Clinical Immunology, Düsseldorf, Germany (GRID:grid.411327.2) (ISNI:0000 0001 2176 9917) 
153  RIKEN Center for Integrative Medical Sciences, Laboratory for Medical Science Mathematics, Yokohama, Japan (GRID:grid.509459.4) (ISNI:0000 0004 0472 0267); RIKEN Center for Integrative Medical Sciences, Yokohama, Japan (GRID:grid.509459.4) (ISNI:0000 0004 0472 0267) 
154  Friedrich-Ebert-Hospital, Department of Internal Medicine/Hematology, Neumünster, Germany (GRID:grid.419890.d) 
155  Yale University, Departments of Dermatology and Pathology, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710) 
156  Barcelona Supercomputing Center (BSC), Barcelona, Spain (GRID:grid.10097.3f) (ISNI:0000 0004 0387 1602); Universitat Pompeu Fabra (UPF), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299) 
157  University of Oxford, Radcliffe Department of Medicine, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948) 
158  McGill University, Canadian Center for Computational Genomics, Montreal, Canada (GRID:grid.14709.3b) (ISNI:0000 0004 1936 8649); McGill University, Department of Human Genetics, Montreal, Canada (GRID:grid.14709.3b) (ISNI:0000 0004 1936 8649) 
159  Tampere University and Tays Cancer Center, Tampere University Hospital, Faculty of Medicine and Health Technology, Tampere, Finland (GRID:grid.412330.7) (ISNI:0000 0004 0628 2985) 
160  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK (GRID:grid.415967.8) (ISNI:0000 0000 9965 1030) 
161  Centre Léon Bérard, Translational Research and Innovation, Lyon, France (GRID:grid.418116.b) (ISNI:0000 0001 0200 3174) 
162  Fox Chase Cancer Center, Philadelphia, USA (GRID:grid.249335.a) (ISNI:0000 0001 2218 7820) 
163  World Health Organization, International Agency for Research on Cancer, Lyon, France (GRID:grid.17703.32) (ISNI:0000000405980095) 
164  Earlham Institute, Norwich, UK (GRID:grid.421605.4) (ISNI:0000 0004 0447 4123); University of East Anglia, Norwich Medical School, Norwich, UK (GRID:grid.8273.e) (ISNI:0000 0001 1092 7967) 
165  Radboud University, Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands (GRID:grid.5590.9) (ISNI:0000000122931605) 
166  University of Toronto, Department of Medical Biophysics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); CRUK Manchester Institute and Centre, Manchester, UK (GRID:grid.17063.33); University of Toronto, Department of Radiation Oncology, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); University of Manchester, Division of Cancer Sciences, Manchester Cancer Research Centre, Manchester, UK (GRID:grid.5379.8) (ISNI:0000000121662407); Princess Margaret Cancer Centre, Radiation Medicine Program, Toronto, Canada (GRID:grid.415224.4) (ISNI:0000 0001 2150 066X) 
167  The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
168  Harvard Medical School, Department of Pathology, Brigham and Women’s Hospital, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
169  The Johns Hopkins University School of Medicine, Department of Surgery, Division of Thoracic Surgery, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311) 
170  The Netherlands Cancer Institute, Oncode Institute, Division of Molecular Pathology, Amsterdam, The Netherlands (GRID:grid.430814.a) (ISNI:0000 0001 0674 1393) 
171  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Dana-Farber Cancer Institute, Department of Medical Oncology, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910); University of California Santa Cruz, Department of Biomolecular Engineering, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917); University of California Santa Cruz, UC Santa Cruz Genomics Institute, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
172  Technical University of Denmark, Center for Biological Sequence Analysis, Department of Bio and Health Informatics, Lyngby, Denmark (GRID:grid.5170.3) (ISNI:0000 0001 2181 8870); University of Copenhagen, Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark (GRID:grid.5254.6) (ISNI:0000 0001 0674 042X) 
173  University of Queensland, St. Lucia, Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537); University of Queensland, St. Lucia, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537) 
174  Universidade de Santiago de Compostela, Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS), Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645); (CiMUS), Universidade de Santiago de Compostela, Department of Zoology, Genetics and Physical Anthropology, Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645); Universidade de Vigo, The Biomedical Research Centre (CINBIO), Vigo, Spain (GRID:grid.6312.6) (ISNI:0000 0001 2097 6738) 
175  Oregon Health and Science University, Biomedical Engineering, Portland, USA (GRID:grid.5288.7) (ISNI:0000 0000 9758 5690) 
176  German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Institute of Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373) 
177  Federal Ministry of Education and Research, Berlin, Germany (GRID:grid.5586.e) (ISNI:0000 0004 0639 2885) 
178  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Dana-Farber Cancer Institute, Department of Medical Oncology, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910) 
179  University of Sydney, Melanoma Institute Australia, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
180  University Hospital Muenster, Pediatric Hematology and Oncology, Muenster, Germany (GRID:grid.16149.3b) (ISNI:0000 0004 0551 4246) 
181  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Foundation Medicine, Inc, Cambridge, USA (GRID:grid.418158.1) (ISNI:0000 0004 0534 4718) 
182  Stanford University School of Medicine, Department of Biomedical Data Science, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956); Stanford University School of Medicine, Department of Genetics, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956) 
183  University of California, Bakar Computational Health Sciences Institute and Department of Pediatrics, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811) 
184  Oslo University Hospital, The Norwegian Radium Hospital, Department of Cancer Genetics, Institute for Cancer Research, Oslo, Norway (GRID:grid.55325.34) (ISNI:0000 0004 0389 8485); University of Oslo, Institute of Clinical Medicine, Faculty of Medicine, Oslo, Norway (GRID:grid.5510.1) (ISNI:0000 0004 1936 8921) 
185  National Institutes of Health, National Cancer Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165) 
186  Royal Marsden NHS Foundation Trust, London and Sutton, UK (GRID:grid.5072.0) (ISNI:0000 0001 0304 893X) 
187  European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Cambridge, UK (GRID:grid.225360.0) (ISNI:0000 0000 9709 7726); European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany (GRID:grid.4709.a) (ISNI:0000 0004 0495 846X) 
188  University of Cambridge, Department of Oncology, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); University of Cambridge, Li Ka Shing Centre, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
189  Institut Gustave Roussy, Villejuif, France (GRID:grid.14925.3b) (ISNI:0000 0001 2284 9388) 
190  University of Barcelona, Anatomia Patológica, Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (GRID:grid.5841.8) (ISNI:0000 0004 1937 0247); Spanish Ministry of Science and Innovation, Madrid, Spain (GRID:grid.451322.3) (ISNI:0000 0004 1770 9462) 
191  University of Michigan Comprehensive Cancer Center, Ann Arbor, USA (GRID:grid.412590.b) (ISNI:0000 0000 9081 2336) 
192  University of Bern, Department for BioMedical Research, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); University Hospital and University of Bern, Department of Medical Oncology, Inselspital, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); University of Bern, Graduate School for Cellular and Biomedical Sciences, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157) 
193  University and Hospital Trust of Verona, Department of Diagnostics and Public Health, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X); University and Hospital Trust of Verona, ARC-Net Centre for Applied Research on Cancer, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
194  University of Pavia, Pavia, Italy (GRID:grid.8982.b) (ISNI:0000 0004 1762 5736) 
195  University of Alabama at Birmingham, Birmingham, USA (GRID:grid.265892.2) (ISNI:0000000106344187) 
196  Toronto General Hospital, UHN Program in BioSpecimen Sciences, Toronto, Canada (GRID:grid.417184.f) (ISNI:0000 0001 0661 1177) 
197  Icahn School of Medicine at Mount Sinai, Department of Urology, New York, USA (GRID:grid.59734.3c) (ISNI:0000 0001 0670 2351) 
198  University of Tasmania, Sandy Bay Campus, Centre for Law and Genetics, Hobart, Australia (GRID:grid.1009.8) (ISNI:0000 0004 1936 826X) 
199  German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Heidelberg University, Faculty of Biosciences, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373) 
200  Division of Anatomic Pathology, Mayo Clinic, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
201  University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X); University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432) 
202  National Institutes of Health, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165) 
203  University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432); Wollongong Hospital, Illawarra Shoalhaven Local Health District L3 Illawarra Cancer Care Centre, Wollongong, Australia (GRID:grid.417154.2) (ISNI:0000 0000 9781 7439) 
204  Ontario Institute for Cancer Research, Genome Informatics Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); BioForA, French National Institute for Agriculture, Food, and Environment (INRAE), ONF, Orléans, France (GRID:grid.419890.d) 
205  Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University School of Medicine, Department of Oncology, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311); Johns Hopkins University, Department of Biostatistics, Bloomberg School of Public Health, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311) 
206  Salford Royal NHS Foundation Trust, Salford, UK (GRID:grid.412346.6) (ISNI:0000 0001 0237 2025); Memorial Sloan Kettering Cancer Center, Center for Molecular Oncology, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
207  University of California San Diego, San Diego, USA (GRID:grid.266100.3) (ISNI:0000 0001 2107 4242) 
208  Division of Experimental Pathology, Mayo Clinic, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
209  University of Sydney, Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X); Westmead Hospital, Department of Gynaecological Oncology, Sydney, Australia (GRID:grid.413252.3) (ISNI:0000 0001 0180 6477) 
210  PDXen Biosystems Inc, Seoul, South Korea (GRID:grid.66859.34) 
211  Korea Advanced Institute of Science and Technology, Daejeon, South Korea (GRID:grid.37172.30) (ISNI:0000 0001 2292 0500) 
212  Electronics and Telecommunications Research Institute, Daejeon, South Korea (GRID:grid.36303.35) (ISNI:0000 0000 9148 4899) 
213  Institut National du Cancer (INCA), Boulogne-Billancourt, France (GRID:grid.455095.8) (ISNI:0000 0001 2189 059X) 
214  The University of Texas MD Anderson Cancer Center, Department of Bioinformatics and Computational Biology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); University of Alabama at Birmingham, Department of Genetics, Informatics Institute, Birmingham, USA (GRID:grid.265892.2) (ISNI:0000000106344187) 
215  National Cancer Centre, Division of Medical Oncology, Singapore, Singapore (GRID:grid.410724.4) (ISNI:0000 0004 0620 9745) 
216  University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432); University of Sydney, Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
217  University and Hospital Trust of Verona, Medical Oncology, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
218  University Hospital Schleswig-Holstein, Department of Pediatrics, Kiel, Germany (GRID:grid.412468.d) (ISNI:0000 0004 0646 2097) 
219  Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University Health Network, Hepatobiliary/Pancreatic Surgical Oncology Program, Toronto, Canada (GRID:grid.231844.8) (ISNI:0000 0004 0474 0428) 
220  University of Auckland, School of Biological Sciences, Auckland, New Zealand (GRID:grid.9654.e) (ISNI:0000 0004 0372 3343) 
221  University of Melbourne, Department of Surgery, Parkville, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X); Royal Children’s Hospital, The Murdoch Children’s Research Institute, Parkville, Australia (GRID:grid.416107.5) (ISNI:0000 0004 0614 0346); Walter and Eliza Hall Institute, Parkville, Australia (GRID:grid.1042.7) (ISNI:0000 0004 0432 4889) 
222  Vancouver Prostate Centre, Vancouver, Canada (GRID:grid.412541.7) (ISNI:0000 0001 0684 7796) 
223  University Health Network, Hepatobiliary/Pancreatic Surgical Oncology Program, Toronto, Canada (GRID:grid.231844.8) (ISNI:0000 0004 0474 0428); Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (GRID:grid.416166.2) (ISNI:0000 0004 0473 9881) 
224  The Institute of Cancer Research, London, UK (GRID:grid.18886.3f); Earlham Institute, Norwich, UK (GRID:grid.421605.4) (ISNI:0000 0004 0447 4123); University of East Anglia, Norwich Medical School, Norwich, UK (GRID:grid.8273.e) (ISNI:0000 0001 1092 7967); University of East Anglia, Norwich, UK (GRID:grid.8273.e) (ISNI:0000 0001 1092 7967) 
225  Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University School of Medicine, Department of Oncology, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311) 
226  University and Hospital Trust of Verona, Department of Pathology and Diagnostics, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X); University and Hospital Trust of Verona, ARC-Net Centre for Applied Research on Cancer, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
227  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Norfolk and Norwich University Hospital NHS Trust, Norwich, UK (GRID:grid.240367.4) (ISNI:0000 0004 0445 7876) 
228  Victorian Institute of Forensic Medicine, Southbank, Australia (GRID:grid.433802.e) (ISNI:0000 0004 0465 4247) 
229  Baylor College of Medicine, Human Genome Sequencing Center, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X) 
230  University of Melbourne, Peter MacCallum Cancer Centre, Melbourne, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X) 
231  University of California Santa Cruz, UC Santa Cruz Genomics Institute, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
232  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Massachusetts General Hospital, Physics Division, Optimization and Systems Biology Lab, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
233  Baylor College of Medicine, Department of Medicine, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X) 
234  University of Cologne, Cologne, Germany (GRID:grid.6190.e) (ISNI:0000 0000 8580 3777) 
235  International Genomics Consortium, Phoenix, USA (GRID:grid.450294.e) (ISNI:0000 0004 0641 0756) 
236  Ontario Institute for Cancer Research, Genomics Research Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
237  The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); Barking Havering and Redbridge University Hospitals NHS Trust, Romford, UK (GRID:grid.439436.f) (ISNI:0000 0004 0459 7289) 
238  University of Sydney, Children’s Hospital at Westmead, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
239  University and Hospital Trust of Verona, Department of Medicine, Section of Endocrinology, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
240  Memorial Sloan Kettering Cancer Center, Computational Biology Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); ETH Zurich, Department of Biology, Zürich, Switzerland (GRID:grid.5801.c) (ISNI:0000 0001 2156 2780); ETH Zurich, Department of Computer Science, Zurich, Switzerland (GRID:grid.5801.c) (ISNI:0000 0001 2156 2780); SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland (GRID:grid.419765.8) (ISNI:0000 0001 2223 3006); Weill Cornell Medical College, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
241  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); University of Cambridge, Addenbrooke’s Hospital, Academic Department of Medical Genetics, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); MRC Cancer Unit, University of Cambridge, Cambridge, UK (GRID:grid.415041.5) 
242  University of North Carolina at Chapel Hill, Departments of Pediatrics and Genetics, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
243  Seven Bridges Genomics, Charlestown, USA (GRID:grid.492568.4) 
244  Stanford University School of Medicine, Department of Biomedical Data Science, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956); Stanford University School of Medicine, Department of Genetics, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956); Annai Systems, Inc, Carlsbad, USA (GRID:grid.168010.e) 
245  University of Padua, Department of Pathology, General Hospital of Treviso, Department of Medicine, Treviso, Italy (GRID:grid.5608.b) (ISNI:0000 0004 1757 3470) 
246  University of Lausanne, Department of Computational Biology, Lausanne, Switzerland (GRID:grid.9851.5) (ISNI:0000 0001 2165 4204); University of Geneva Medical School, Department of Genetic Medicine and Development, Geneva, Switzerland (GRID:grid.8591.5) (ISNI:0000 0001 2322 4988); University of Geneva, Swiss Institute of Bioinformatics, Geneva, Switzerland (GRID:grid.8591.5) (ISNI:0000 0001 2322 4988) 
247  The Francis Crick Institute, London, UK (GRID:grid.451388.3) (ISNI:0000 0004 1795 1830); University of Leuven, Leuven, Belgium (GRID:grid.5596.f) (ISNI:0000 0001 0668 7884) 
248  Universitat Pompeu Fabra (UPF), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); University of Tübingen, Institute of Medical Genetics and Applied Genomics, Tübingen, Germany (GRID:grid.10392.39) (ISNI:0000 0001 2190 1447) 
249  Genome Institute of Singapore, Computational and Systems Biology, Singapore, Singapore (GRID:grid.418377.e) (ISNI:0000 0004 0620 715X); National University of Singapore, School of Computing, Singapore, Singapore (GRID:grid.4280.e) (ISNI:0000 0001 2180 6431) 
250  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); The Francis Crick Institute, London, UK (GRID:grid.451388.3) (ISNI:0000 0004 1795 1830); University of Oxford, Big Data Institute, Li Ka Shing Centre, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948) 
251  Francis Crick Institute, Biomedical Data Science Laboratory, London, UK (GRID:grid.451388.3) (ISNI:0000 0004 1795 1830); University College London, Bioinformatics Group, Department of Computer Science, London, UK (GRID:grid.83440.3b) (ISNI:0000000121901201) 
252  University of Toronto, The Edward S. Rogers Sr. Department of Electrical and Computer Engineering, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
253  Institut Jules Bordet, Breast Cancer Translational Research Laboratory JC Heuson, Brussels, Belgium (GRID:grid.418119.4) (ISNI:0000 0001 0684 291X); KU Leuven, Department of Oncology, Laboratory for Translational Breast Cancer Research, Leuven, Belgium (GRID:grid.5596.f) (ISNI:0000 0001 0668 7884) 
254  The Barcelona Institute of Science and Technology, Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); Universitat Pompeu Fabra, Research Program on Biomedical Informatics, Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676) 
255  Princess Margaret Cancer Centre, Division of Medical Oncology, Toronto, Canada (GRID:grid.415224.4) (ISNI:0000 0001 2150 066X) 
256  Weill Cornell Medicine, Department of Physiology and Biophysics, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Weill Cornell Medicine, Institute for Computational Biomedicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
257  UPMC Shadyside, Department of Pathology, Pittsburgh, USA (GRID:grid.415596.a) (ISNI:0000 0004 0440 3018) 
258  Independent Consultant, Wellesley, USA (GRID:grid.415596.a) 
259  Uppsala University, Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala, Sweden (GRID:grid.8993.b) (ISNI:0000 0004 1936 9457) 
260  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Washington University School of Medicine, Alvin J. Siteman Cancer Center, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Washington University School of Medicine, St. Louis, Department of Medicine and Department of Genetics, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
261  Hefei University of Technology, Anhui, China (GRID:grid.256896.6) (ISNI:0000 0001 0395 8562) 
262  Cedars-Sinai Medical Center, Center for Bioinformatics and Functional Genomics, Los Angeles, USA (GRID:grid.50956.3f) (ISNI:0000 0001 2152 9905) 
263  Translational Cancer Research Unit, GZA Hospitals St.-Augustinus, Center for Oncological Research, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium (GRID:grid.5284.b) (ISNI:0000 0001 0790 3681) 
264  Vancouver Prostate Centre, Vancouver, Canada (GRID:grid.412541.7) (ISNI:0000 0001 0684 7796); Simon Fraser University, Burnaby, Canada (GRID:grid.61971.38) (ISNI:0000 0004 1936 7494) 
265  University of Pennsylvania, Philadelphia, USA (GRID:grid.25879.31) (ISNI:0000 0004 1936 8972) 
266  Universitat Pompeu Fabra (UPF), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299) 
267  University of Cambridge, Li Ka Shing Centre, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
268  University Hospital Southampton NHS Foundation Trust, Southampton, UK (GRID:grid.430506.4) (ISNI:0000 0004 0465 4079); Royal Marsden NHS Foundation Trust, London and Sutton, UK (GRID:grid.5072.0) (ISNI:0000 0001 0304 893X) 
269  The Wellcome Trust, London, UK (GRID:grid.52788.30) (ISNI:0000 0004 0427 7672) 
270  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); The Hospital for Sick Children, Toronto, Canada (GRID:grid.42327.30) (ISNI:0000 0004 0473 9646) 
271  University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X); Queen Elizabeth University Hospital, Department of Pathology, Glasgow, UK (GRID:grid.511123.5) (ISNI:0000 0004 5988 7216) 
272  QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Australia (GRID:grid.1049.c) (ISNI:0000 0001 2294 1395) 
273  University of Cambridge, Department of Oncology, Centre for Cancer Genetic Epidemiology, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); University of Cambridge, Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
274  Prostate Cancer Canada, Toronto, Canada (GRID:grid.453281.9) (ISNI:0000 0004 4652 6665) 
275  The Institute of Cancer Research, London, UK (GRID:grid.18886.3f); Royal Marsden NHS Foundation Trust, London and Sutton, UK (GRID:grid.5072.0) (ISNI:0000 0001 0304 893X) 
276  Lund University Cancer Center at Medicon Village, Lund University, Department of Laboratory Medicine, Translational Cancer Research, Lund, Sweden (GRID:grid.4514.4) (ISNI:0000 0001 0930 2361) 
277  Heidelberg University, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin, New BIH Digital Health Center, Berlin, Germany (GRID:grid.6363.0) (ISNI:0000 0001 2218 4662) 
278  European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany (GRID:grid.4709.a) (ISNI:0000 0004 0495 846X) 
279  The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (GRID:grid.466571.7) (ISNI:0000 0004 1756 6246); Econometrics and Health (GRECS), UdG, Research Group on Statistics, Barcelona, Spain (GRID:grid.466571.7) 
280  Icelandic Cancer Registry, Icelandic Cancer Society, Reykjavik, Iceland (GRID:grid.507118.a) (ISNI:0000 0001 0329 4954) 
281  Weill Cornell Medical College, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
282  Fourth Military Medical University, State Key Laboratory of Cancer Biology, and Xijing Hospital of Digestive Diseases, Shaanxi, China (GRID:grid.233520.5) (ISNI:0000 0004 1761 4404) 
283  Surgical Pathology Unit, University of Padua, Department of Medicine (DIMED), Padua, Italy (GRID:grid.5608.b) (ISNI:0000 0004 1757 3470) 
284  Dana-Farber Cancer Institute, Department of Cancer Biology, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910) 
285  Rigshospitalet, Copenhagen, Denmark (GRID:grid.475435.4) 
286  National Institutes of Health, Center for Cancer Genomics, National Cancer Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165) 
287  Ontario Institute for Cancer Research, Genome Informatics Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Montreal, Department of Biochemistry and Molecular Medicine, Montreal, Canada (GRID:grid.14848.31) (ISNI:0000 0001 2292 3357) 
288  James Cook University, Australian Institute of Tropical Health and Medicine, Douglas, Australia (GRID:grid.1011.1) (ISNI:0000 0004 0474 1797) 
289  Istituto Neurologico Besta, Department of Neuro-Oncology, Milano, Italy (GRID:grid.10097.3f) 
290  The Francis Crick Institute, London, UK (GRID:grid.451388.3) (ISNI:0000 0004 1795 1830) 
291  Bioplatforms Australia, North Ryde, Australia (GRID:grid.484025.f) 
292  MRC Cancer Unit, University of Cambridge, Cambridge, UK (GRID:grid.415041.5) 
293  University College London Cancer Institute, Department of Pathology (Research), London, UK (GRID:grid.83440.3b) (ISNI:0000000121901201) 
294  Princess Margaret Cancer Centre, Department of Surgical Oncology, Toronto, Canada (GRID:grid.415224.4) (ISNI:0000 0001 2150 066X) 
295  Erasmus Medical Center, Department of Medical Oncology, Josephine Nefkens Institute and Cancer Genomics Centre, Rotterdam, The Netherlands (GRID:grid.5645.2) (ISNI:000000040459992X) 
296  The University of Queensland Thoracic Research Centre, The Prince Charles Hospital, Brisbane, Australia (GRID:grid.415184.d) (ISNI:0000 0004 0614 0266) 
297  European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Cambridge, UK (GRID:grid.225360.0) (ISNI:0000 0000 9709 7726); Universidade do Porto, CIBIO/InBIO - Research Center in Biodiversity and Genetic Resources, Vairão, Portugal (GRID:grid.5808.5) (ISNI:0000 0001 1503 7226) 
298  HCA Laboratories, London, UK (GRID:grid.420746.3) (ISNI:0000 0001 1887 2462); University of Liverpool, Liverpool, UK (GRID:grid.10025.36) (ISNI:0000 0004 1936 8470) 
299  University of Florida, Department of Neurosurgery, Gainesville, USA (GRID:grid.15276.37) (ISNI:0000 0004 1936 8091) 
300  The Barcelona Institute of Science and Technology, Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299) 
301  Graduate School of Medicine, University of Tokyo, Department of Pathology, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X) 
302  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
303  The University of Texas MD Anderson Cancer Center, Department of Genomic Medicine, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
304  Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University Health Network, Hepatobiliary/Pancreatic Surgical Oncology Program, Toronto, Canada (GRID:grid.231844.8) (ISNI:0000 0004 0474 0428); Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (GRID:grid.416166.2) (ISNI:0000 0004 0473 9881) 
305  University of Milano Bicocca, Monza, Italy (GRID:grid.7563.7) (ISNI:0000 0001 2174 1754) 
306  BGI-Shenzhen, Shenzhen, China (GRID:grid.21155.32) (ISNI:0000 0001 2034 1839) 
307  Dana-Farber Cancer Institute, Department of Medical Oncology, Boston, USA (GRID:grid.65499.37) (ISNI:0000 0001 2106 9910) 
308  Oslo University Hospital Ulleval, Department of Pathology, Oslo, Norway (GRID:grid.55325.34) (ISNI:0000 0004 0389 8485) 
309  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard Medical School, Center for Biomedical Informatics, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
310  Barcelona Supercomputing Center (BSC), Barcelona, Spain (GRID:grid.10097.3f) (ISNI:0000 0004 0387 1602); University of Barcelona, Department Biochemistry and Molecular Biomedicine, Barcelona, Spain (GRID:grid.5841.8) (ISNI:0000 0004 1937 0247) 
311  The Jackson Laboratory for Genomic Medicine, Farmington, USA (GRID:grid.249880.f) (ISNI:0000 0004 0374 0039) 
312  National Institutes of Health, Office of Cancer Genomics, National Cancer Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165) 
313  Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
314  The University of Texas MD Anderson Cancer Center, Department of Cancer Biology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); The University of Texas MD Anderson Cancer Center, Department of Surgical Oncology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
315  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Massachusetts General Hospital, Center for Cancer Research, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924); Massachusetts General Hospital, Department of Pathology, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
316  Memorial Sloan Kettering Cancer Center, Department of Pathology, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
317  Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
318  Ontario Institute for Cancer Research, Genome Sequence Informatics, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
319  University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432); University of Sydney, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
320  University of Oxford, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948) 
321  Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386); Academic Urology Group, University of Cambridge, Department of Surgery, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
322  University of Würzburg, Department of Medicine II, Wuerzburg, Germany (GRID:grid.8379.5) (ISNI:0000 0001 1958 8658) 
323  University of Miami, Sylvester Comprehensive Cancer Center, Miami, USA (GRID:grid.26790.3a) (ISNI:0000 0004 1936 8606) 
324  The Barcelona Institute of Science and Technology, Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); Universitat Pompeu Fabra, Research Program on Biomedical Informatics, Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona, Spain (GRID:grid.20522.37) (ISNI:0000 0004 1767 9005) 
325  St. Thomas’s Hospital, London, UK (GRID:grid.425213.3) 
326  Osaka International Cancer Center, Osaka, Japan (GRID:grid.425213.3) 
327  Washington University School of Medicine, Alvin J. Siteman Cancer Center, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
328  Skåne University Hospital, Lund University, Department of Pathology, Lund, Sweden (GRID:grid.411843.b) (ISNI:0000 0004 0623 9987) 
329  University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X); Beatson West of Scotland Cancer Centre, Department of Medical Oncology, Glasgow, UK (GRID:grid.422301.6) (ISNI:0000 0004 0606 0717) 
330  Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (GRID:grid.416166.2) (ISNI:0000 0004 0473 9881) 
331  University of Cambridge, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
332  National Institutes of Health, National Human Genome Research Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165) 
333  University of Melbourne, Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Melbourne, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X) 
334  University of Chicago, Department of Medicine, Section of Hematology/Oncology, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822) 
335  Leibniz Institute for Experimental Virology, Heinrich Pette Institute, Hamburg, Germany (GRID:grid.418481.0) (ISNI:0000 0001 0665 103X); Partner Site Hamburg-Borstel-Lübeck-Riems, German Center for Infection Research (DZIF), Hamburg, Germany (GRID:grid.452463.2) 
336  Aarhus University, Bioinformatics Research Centre (BiRC), Aarhus, Denmark (GRID:grid.7048.b) (ISNI:0000 0001 1956 2722) 
337  Ministry of Science and Technology, Government of India, Department of Biotechnology, New Delhi, India (GRID:grid.410865.e) 
338  Genome Institute of Singapore, Computational and Systems Biology, Singapore, Singapore (GRID:grid.418377.e) (ISNI:0000 0004 0620 715X); National Cancer Centre Singapore, Singapore, Singapore (GRID:grid.410724.4) (ISNI:0000 0004 0620 9745) 
339  Christian-Albrechts-University, Institute of Human Genetics, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986) 
340  Friedrich-Ebert-Hospital, Department of Internal Medicine/Hematology, Neumünster, Germany (GRID:grid.205975.c) 
341  Vancouver Prostate Centre, Vancouver, Canada (GRID:grid.412541.7) (ISNI:0000 0001 0684 7796); University of British Columbia, Department of Urologic Sciences, Vancouver, Canada (GRID:grid.17091.3e) (ISNI:0000 0001 2288 9830) 
342  Stanford University, Department of Internal Medicine, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956) 
343  The University of Texas Health Science Center at Houston, Houston, USA (GRID:grid.267308.8) (ISNI:0000 0000 9206 2401) 
344  Imperial College NHS Trust, Imperial College, London, UK (GRID:grid.7445.2) (ISNI:0000 0001 2113 8111) 
345  University of Frankfurt Medical School, Senckenberg Institute of Pathology, Frankfurt, Germany (GRID:grid.7839.5) (ISNI:0000 0004 1936 9721) 
346  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Massachusetts General Hospital, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
347  UC San Diego Moores Cancer Center, San Diego, USA (GRID:grid.516081.b) (ISNI:0000 0000 9217 9714); UC San Diego School of Medicine, Department of Medicine, Division of Biomedical Informatics, San Diego, USA (GRID:grid.266100.3) (ISNI:0000 0001 2107 4242) 
348  Yale University, Program in Computational Biology and Bioinformatics, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710); The University of Texas Health Science Center, Center for Precision Health, School of Biomedical Informatics, Houston, USA (GRID:grid.468222.8) 
349  Oxford Nanopore Technologies, New York, USA (GRID:grid.468222.8) 
350  University of Tokyo, Institute of Medical Science, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X) 
351  University of California Santa Cruz, UC Santa Cruz Genomics Institute, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917); University of California Santa Cruz, Howard Hughes Medical Institute, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
352  Wakayama Medical University, Wakayama, Japan (GRID:grid.412857.d) (ISNI:0000 0004 1763 1087) 
353  University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208); University of North Carolina at Chapel Hill, Department of Internal Medicine, Division of Medical Oncology, Lineberger Comprehensive Cancer Center, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208); University of Tennessee Health Science Center for Cancer Research, Memphis, USA (GRID:grid.267301.1) (ISNI:0000 0004 0386 9246) 
354  Salford Royal NHS Foundation Trust, Department of Histopathology, Salford, UK (GRID:grid.412346.6) (ISNI:0000 0001 0237 2025); University of Manchester, Faculty of Biology, Medicine and Health, Manchester, UK (GRID:grid.5379.8) (ISNI:0000000121662407) 
355  University of Sydney, Melanoma Institute Australia, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X); QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Australia (GRID:grid.1049.c) (ISNI:0000 0001 2294 1395) 
356  Peking University, BIOPIC, ICG and College of Life Sciences, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319); Peking University, Peking-Tsinghua Center for Life Sciences, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
357  Children’s Hospital of Philadelphia, Philadelphia, USA (GRID:grid.239552.a) (ISNI:0000 0001 0680 8770) 
358  The University of Texas MD Anderson Cancer Center, Department of Bioinformatics and Computational Biology and Department of Systems Biology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
359  German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Institute of Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373) 
360  Karolinska Institute, Stockholm, Sweden (GRID:grid.4714.6) (ISNI:0000 0004 1937 0626) 
361  University of Toronto, The Donnelly Centre, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
362  Hallym University, Department of Medical Genetics, College of Medicine, Chuncheon, South Korea (GRID:grid.256753.0) (ISNI:0000 0004 0470 5964) 
363  Universitat Pompeu Fabra, Department of Experimental and Health Sciences, Institute of Evolutionary Biology (UPF-CSIC), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676) 
364  German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Institute of Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); University Clinics, Health Data Science Unit, Heidelberg, Germany (GRID:grid.411941.8) (ISNI:0000 0000 9194 7179) 
365  Hokkaido University, Sapporo, Japan (GRID:grid.39158.36) (ISNI:0000 0001 2173 7691) 
366  National Cancer Center Hospital, Department of Pathology and Clinical Laboratory, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385) 
367  University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208); University of North Carolina at Chapel Hill, Department of Genetics, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
368  Aarhus University, Department of Mathematics, Aarhus, Denmark (GRID:grid.7048.b) (ISNI:0000 0001 1956 2722); Aarhus University, Bioinformatics Research Centre (BiRC), Aarhus, Denmark (GRID:grid.7048.b) (ISNI:0000 0001 1956 2722) 
369  Simon Fraser University, Burnaby, Canada (GRID:grid.61971.38) (ISNI:0000 0004 1936 7494) 
370  University of Leipzig, Department of Computer Science, Bioinformatics Group, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786); University of Leipzig, Interdisciplinary Center for Bioinformatics, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786); University of Leipzig, Transcriptome Bioinformatics, LIFE Research Center for Civilization Diseases, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786); Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Computational Biology, Jena, Germany (GRID:grid.418245.e) (ISNI:0000 0000 9999 5706) 
371  University of Melbourne Centre for Cancer Research, Melbourne, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X) 
372  The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299) 
373  University of Nebraska Medical Center, Omaha, USA (GRID:grid.266813.8) (ISNI:0000 0001 0666 4105) 
374  University of Queensland, St. Lucia, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537); QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Australia (GRID:grid.1049.c) (ISNI:0000 0001 2294 1395) 
375  Syntekabio Inc, Daejeon, South Korea (GRID:grid.256753.0) 
376  Academic Medical Center, Department of Pathology, Amsterdam, The Netherlands (GRID:grid.5650.6) (ISNI:0000000404654431) 
377  Aarhus University Hospital, Department of Molecular Medicine (MOMA), Aarhus N, Denmark (GRID:grid.154185.c) (ISNI:0000 0004 0512 597X) 
378  BGI-Shenzhen, Shenzhen, China (GRID:grid.21155.32) (ISNI:0000 0001 2034 1839); China National GeneBank-Shenzhen, Shenzhen, China (GRID:grid.507779.b) (ISNI:0000 0004 4910 5858) 
379  German Cancer Research Center (DKFZ), Division of Molecular Genetics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
380  Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386) 
381  Hong Kong University of Science and Technology, Clear Water Bay, Division of Life Science and Applied Genomics Center, Hong Kong, China (GRID:grid.24515.37) (ISNI:0000 0004 1937 1450) 
382  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Icahn School of Medicine at Mount Sinai, New York, USA (GRID:grid.59734.3c) (ISNI:0000 0001 0670 2351) 
383  Geneplus-Shenzhen, Shenzhen, China (GRID:grid.419890.d); Xi’an Jiaotong University, School of Computer Science and Technology, Xi’an, China (GRID:grid.43169.39) (ISNI:0000 0001 0599 1243) 
384  Ontario Institute for Cancer Research, Genomics Research Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); AbbVie, North Chicago, USA (GRID:grid.431072.3) (ISNI:0000 0004 0572 4227) 
385  Charité – University Medicine Berlin, Institute of Pathology, Berlin, Germany (GRID:grid.6363.0) (ISNI:0000 0001 2218 4662) 
386  British Columbia Cancer Agency, Centre for Translational and Applied Genomics, Vancouver, Canada (GRID:grid.248762.d) (ISNI:0000 0001 0702 3000) 
387  Edinburgh Royal Infirmary, Edinburgh, UK (GRID:grid.418716.d) (ISNI:0000 0001 0709 1919) 
388  Max Delbrück Center for Molecular Medicine, Berlin Institute for Medical Systems Biology, Berlin, Germany (GRID:grid.419491.0) (ISNI:0000 0001 1014 0849) 
389  Institute of Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); Heidelberg University, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); University Hospital, Department of Pediatric Immunology, Hematology and Oncology, Heidelberg, Germany (GRID:grid.5253.1) (ISNI:0000 0001 0328 4908); German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany (GRID:grid.482664.a) 
390  Johns Hopkins University School of Medicine, Department of Urology, James Buchanan Brady Urological Institute, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311) 
391  The University of Tokyo, Department of Preventive Medicine, Graduate School of Medicine, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X) 
392  Baylor College of Medicine, Department of Molecular and Cellular Biology, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X); Baylor College of Medicine, Department of Pathology and Immunology, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X); Michael E. DeBakey Veterans Affairs Medical Center, Houston, USA (GRID:grid.413890.7) (ISNI:0000 0004 0420 5521) 
393  Technical University of Denmark, Lyngby, Denmark (GRID:grid.5170.3) (ISNI:0000 0001 2181 8870) 
394  Hanyang University, Department of Pathology, College of Medicine, Seoul, South Korea (GRID:grid.49606.3d) (ISNI:0000 0001 1364 9317) 
395  University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X); Glasgow Royal Infirmary, West of Scotland Pancreatic Unit, Glasgow, UK (GRID:grid.411714.6) (ISNI:0000 0000 9825 7840); University of Glasgow, Glasgow Royal Infirmary, Academic Unit of Surgery, School of Medicine, College of Medical, Veterinary and Life Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X) 
396  Ulsan University, Department of Pathology, Asan Medical Center, College of Medicine, Songpa-gu, South Korea (GRID:grid.267370.7) (ISNI:0000 0004 0533 4667) 
397  Science Writer, Garrett Park, USA (GRID:grid.10698.36) 
398  Ontario Institute for Cancer Research, International Cancer Genome Consortium (ICGC)/ICGC Accelerating Research in Genomic Oncology (ARGO) Secretariat, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
399  European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany (GRID:grid.4709.a) (ISNI:0000 0004 0495 846X); University of Ljubljana, Ljubljana, Slovenia (GRID:grid.8954.0) (ISNI:0000 0001 0721 6013) 
400  University of Chicago, Department of Public Health Sciences, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822); NorthShore University HealthSystem, Research Institute, Evanston, USA (GRID:grid.240372.0) (ISNI:0000 0004 0400 4439) 
401  University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432) 
402  University Hospital and University of Bern, Department of Medical Oncology, Inselspital, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); University of Bern, Department for Biomedical Research, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157) 
403  RIKEN Center for Integrative Medical Sciences, Laboratory for Medical Science Mathematics, Yokohama, Japan (GRID:grid.509459.4) (ISNI:0000 0004 0472 0267) 
404  McGill University and Génome Québec Innovation Centre, Centre of Genomics and Policy, Montreal, Canada (GRID:grid.411640.6) 
405  University of North Carolina at Chapel Hill, Carolina Center for Genome Sciences, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
406  Cancer Research UK, London, UK (GRID:grid.11485.39) (ISNI:0000 0004 0422 0975) 
407  Indivumed GmbH, Hamburg, Germany (GRID:grid.37172.30) 
408  Genome Integration Data Center, Syntekabio, Inc, Daejeon, South Korea (GRID:grid.37172.30) 
409  Oxford Nanopore Technologies, New York, USA (GRID:grid.154185.c) 
410  Memorial Sloan Kettering Cancer Center, Computational Biology Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); ETH Zurich, Department of Biology, Zürich, Switzerland (GRID:grid.5801.c) (ISNI:0000 0001 2156 2780); ETH Zurich, Department of Computer Science, Zurich, Switzerland (GRID:grid.5801.c) (ISNI:0000 0001 2156 2780); SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland (GRID:grid.419765.8) (ISNI:0000 0001 2223 3006); University Hospital Zurich, Zurich, Switzerland (GRID:grid.412004.3) (ISNI:0000 0004 0478 9977) 
411  Swiss Institute of Bioinformatics, Clinical Bioinformatics, Geneva, Switzerland (GRID:grid.419765.8) (ISNI:0000 0001 2223 3006); University Hospital Zurich, Institute for Pathology and Molecular Pathology, Zurich, Switzerland (GRID:grid.412004.3) (ISNI:0000 0004 0478 9977); University of Zurich, Institute of Molecular Life Sciences, Zurich, Switzerland (GRID:grid.7400.3) (ISNI:0000 0004 1937 0650) 
412  University of Edinburgh, MRC Human Genetics Unit, MRC IGMM, Edinburgh, UK (GRID:grid.4305.2) (ISNI:0000 0004 1936 7988) 
413  German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
414  Cedars-Sinai Medical Center, Women’s Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Los Angeles, USA (GRID:grid.50956.3f) (ISNI:0000 0001 2152 9905) 
415  University of Zagreb, Department of Biology, Bioinformatics Group, Division of Molecular Biology, Faculty of Science, Zagreb, Croatia (GRID:grid.4808.4) (ISNI:0000 0001 0657 4636) 
416  University Hospital Schleswig-Holstein, Department for Internal Medicine II, Kiel, Germany (GRID:grid.412468.d) (ISNI:0000 0004 0646 2097) 
417  University of Queensland, St. Lucia, Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537); Genetics and Molecular Pathology, SA Pathology, Adelaide, Australia (GRID:grid.414733.6) (ISNI:0000 0001 2294 430X) 
418  National Cancer Center Hospital, Department of Gastric Surgery, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385) 
419  National Cancer Center Research Institute, Department of Bioinformatics, Division of Cancer Genomics, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385) 
420  University College London, London, UK (GRID:grid.83440.3b) (ISNI:0000000121901201) 
421  The George Washington University, School of Medicine and Health Science, Department of Surgery, Washington, USA (GRID:grid.253615.6) (ISNI:0000 0004 1936 9510); National Cancer Institute, National Institutes of Health, Endocrine Oncology Branch, Center for Cancer Research, Bethesda, USA (GRID:grid.48336.3a) (ISNI:0000 0004 1936 8075) 
422  Macquarie University, Melanoma Institute Australia, Sydney, Australia (GRID:grid.1004.5) (ISNI:0000 0001 2158 5405) 
423  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Massachusetts Institute of Technology, MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, USA (GRID:grid.116068.8) (ISNI:0000 0001 2341 2786) 
424  University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432); University of Sydney, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X); Royal Prince Alfred Hospital, Tissue Pathology and Diagnostic Oncology, Sydney, Australia (GRID:grid.413249.9) (ISNI:0000 0004 0385 0051) 
425  Barking Havering and Redbridge University Hospitals NHS Trust, Romford, UK (GRID:grid.439436.f) (ISNI:0000 0004 0459 7289) 
426  University and Hospital Trust of Verona, Department of Surgery, Pancreas Institute, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X); Khon Kaen University, Cholangiocarcinoma Screening and Care Program and Liver Fluke and Cholangiocarcinoma Research Centre, Faculty of Medicine, Khon Kaen, Thailand (GRID:grid.9786.0) (ISNI:0000 0004 0470 0856) 
427  Weill Cornell Medicine, Department of Physiology and Biophysics, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Weill Cornell Medicine, Institute for Computational Biomedicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Controlled Department and Institution, New York, USA (GRID:grid.5386.8); Weill Cornell Medicine, Englander Institute for Precision Medicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
428  National Cancer Center, Gyeonggi, South Korea (GRID:grid.410914.9) (ISNI:0000 0004 0628 9810) 
429  Ewha Womans University, Department of Biochemistry, College of Medicine, Seoul, South Korea (GRID:grid.255649.9) (ISNI:0000 0001 2171 7754) 
430  University of California San Diego, Health Sciences Department of Biomedical Informatics, La Jolla, USA (GRID:grid.266100.3) (ISNI:0000 0001 2107 4242) 
431  National Cancer Centre Korea, Research Core Center, Goyang-si, South Korea (GRID:grid.410914.9) (ISNI:0000 0004 0628 9810) 
432  Sungkyunkwan University School of Medicine, Department of Health Sciences and Technology, Seoul, South Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X); Samsung Genome Institute, Seoul, South Korea (GRID:grid.264381.a) 
433  Dana-Farber/Brigham and Women’s Cancer Center, Breast Oncology Program, Boston, USA (GRID:grid.417747.6) (ISNI:0000 0004 0460 3896); Memorial Sloan Kettering Cancer Center, Department of Surgery, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); Brigham and Women’s Hospital, Division of Breast Surgery, Boston, USA (GRID:grid.62560.37) (ISNI:0000 0004 0378 8294) 
434  Christian-Albrechts-University, Hematopathology Section, Institute of Pathology, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986) 
435  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); University of Bergen, Department of Clinical Science, Bergen, Norway (GRID:grid.7914.b) (ISNI:0000 0004 1936 7443) 
436  Uppsala University, Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala, Sweden (GRID:grid.8993.b) (ISNI:0000 0004 1936 9457); Polish Academy of Sciences, Institute of Computer Science, Warsawa, Poland (GRID:grid.413454.3) (ISNI:0000 0001 1958 0162) 
437  Hopp Children’s Cancer Center (KiTZ), Heidelberg, Germany (GRID:grid.510964.f); Functional and Structural Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
438  Functional and Structural Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
439  National Institutes of Health, Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165) 
440  University of Leipzig, Interdisciplinary Center for Bioinformatics, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786); University of Leipzig, Transcriptome Bioinformatics, LIFE Research Center for Civilization Diseases, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786) 
441  University of Leipzig, Institute for Medical Informatics Statistics and Epidemiology, Leipzig, Germany (GRID:grid.9647.c) (ISNI:0000 0004 7669 9786) 
442  The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); The University of Texas MD Anderson Cancer Center, Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
443  Georg-Augusts-University of Göttingen, Department of Hematology and Oncology, Göttingen, Germany (GRID:grid.7450.6) (ISNI:0000 0001 2364 4210) 
444  Yale University, Department of Molecular Biophysics and Biochemistry, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710); Yale University, Program in Computational Biology and Bioinformatics, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710) 
445  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Massachusetts General Hospital, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
446  University of Duisburg-Essen, Institute of Cell Biology (Cancer Research), Essen, Germany (GRID:grid.5718.b) (ISNI:0000 0001 2187 5445) 
447  Karolinska Institute, Stockholm, Sweden (GRID:grid.4714.6) (ISNI:0000 0004 1937 0626); King’s College London and Guy’s and St. Thomas’ NHS Foundation Trust, London, UK (GRID:grid.420545.2) (ISNI:0000 0004 0489 3985) 
448  Van Andel Research Institute, Center for Epigenetics, Grand Rapids, USA (GRID:grid.251017.0) (ISNI:0000 0004 0406 2057) 
449  Royal Brisbane and Women’s Hospital, The University of Queensland Centre for Clinical Research, Herston, Australia (GRID:grid.416100.2) (ISNI:0000 0001 0688 4634) 
450  University of Cologne, Department of Pediatric Oncology and Hematology, Cologne, Germany (GRID:grid.6190.e) (ISNI:0000 0000 8580 3777); University of Düsseldorf, Düsseldorf, Germany (GRID:grid.411327.2) (ISNI:0000 0001 2176 9917) 
451  University Hospital and University of Bern, Department of Medical Oncology, Inselspital, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); University of Bern, Graduate School for Cellular and Biomedical Sciences, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); University of Bern, Department for Biomedical Research, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157) 
452  Institut Jules Bordet, Department of Pathology, Brussels, Belgium (GRID:grid.418119.4) (ISNI:0000 0001 0684 291X) 
453  Sahlgrenska Academy at University of Gothenburg, Institute of Biomedicine, Gothenburg, Sweden (GRID:grid.8761.8) (ISNI:0000 0000 9919 9582) 
454  McGill University, Department of Human Genetics, Montreal, Canada (GRID:grid.14709.3b) (ISNI:0000 0004 1936 8649) 
455  Children’s Medical Research Institute, Sydney, Australia (GRID:grid.414235.5) (ISNI:0000 0004 0619 2154) 
456  Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin, New BIH Digital Health Center, Berlin, Germany (GRID:grid.6363.0) (ISNI:0000 0001 2218 4662) 
457  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Massachusetts General Hospital, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924); RIKEN Center for Integrative Medical Sciences, Laboratory for Medical Science Mathematics, Yokohama, Japan (GRID:grid.509459.4) (ISNI:0000 0004 0472 0267) 
458  The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); The University of Texas MD Anderson Cancer Center, Department of Genomic Medicine, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
459  ILSbio, LLC Biobank, Chestertown, USA (GRID:grid.492568.4) 
460  Yale University, Program in Computational Biology and Bioinformatics, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710) 
461  Hanyang University, Institute for Bioengineering and Biopharmaceutical Research (IBBR), Seoul, South Korea (GRID:grid.49606.3d) (ISNI:0000 0001 1364 9317) 
462  University of California Santa Cruz, Department of Statistics, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
463  Institute of Biomedical Sciences, Academia Sinica, National Genotyping Center, Taipei, Taiwan (GRID:grid.482251.8) (ISNI:0000 0004 0633 7958) 
464  Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics/Otto Warburg Laboratory Gene Regulation and Systems Biology of Cancer, Berlin, Germany (GRID:grid.419538.2) (ISNI:0000 0000 9071 0620) 
465  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); The Institute of Cancer Research, London, UK (GRID:grid.18886.3f) 
466  McGill University and Genome Quebec Innovation Centre, Montreal, Canada (GRID:grid.411640.6) 
467  biobyte solutions GmbH, Heidelberg, Germany (GRID:grid.431797.f) 
468  Memorial Sloan Kettering Cancer Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); New York University, Gynecologic Oncology, NYU Laura and Isaac Perlmutter Cancer Center, New York, USA (GRID:grid.137628.9) (ISNI:0000 0004 1936 8753) 
469  Washington University School of Medicine, Division of Oncology, Stem Cell Biology Section, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
470  The University of Texas MD Anderson Cancer Center, Department of Bioinformatics and Computational Biology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); Baylor College of Medicine, Quantitative and Computational Biosciences Graduate Program, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X); The University of Texas MD Anderson Cancer Center, Department of Systems Biology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
471  German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); German Cancer Research Center (DKFZ), Division of Molecular Genetics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
472  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard University, Cambridge, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
473  National Cancer Institute, National Institutes of Health, Urologic Oncology Branch, Center for Cancer Research, Bethesda, USA (GRID:grid.48336.3a) (ISNI:0000 0004 1936 8075) 
474  University of Oslo, Oslo, Norway (GRID:grid.5510.1) (ISNI:0000 0004 1936 8921) 
475  Memorial Sloan Kettering Cancer Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); Weill Cornell Medicine, Department of Physiology and Biophysics, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Weill Cornell Medicine, Institute for Computational Biomedicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
476  Princess Margaret Cancer Centre, Radiation Medicine Program, Toronto, Canada (GRID:grid.415224.4) (ISNI:0000 0001 2150 066X); University of Toronto, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
477  Peking University, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319); Peking University, School of Life Sciences, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
478  Leidos Biomedical Research, Inc, McLean, USA (GRID:grid.419407.f) (ISNI:0000 0004 4665 8158) 
479  The Jackson Laboratory for Genomic Medicine, Farmington, USA (GRID:grid.249880.f) (ISNI:0000 0004 0374 0039); Yale University, Department of Molecular Biophysics and Biochemistry, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710); Yale University, Program in Computational Biology and Bioinformatics, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710) 
480  University of Barcelona, Hematology, Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (GRID:grid.5841.8) (ISNI:0000 0004 1937 0247) 
481  Queen Mary University of London, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, London, UK (GRID:grid.4868.2) (ISNI:0000 0001 2171 1133); Second Military Medical University, Shanghai, China (GRID:grid.73113.37) (ISNI:0000 0004 0369 1660) 
482  Chinese Cancer Genome Consortium, Shenzhen, China (GRID:grid.73113.37); Beijing Hospital, Department of Medical Oncology, Beijing, China (GRID:grid.414350.7) (ISNI:0000 0004 0447 1045); Peking University Cancer Hospital and Institute, Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing, China (GRID:grid.412474.0) (ISNI:0000 0001 0027 0586) 
483  Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
484  Institute for Systems Biology, Seattle, USA (GRID:grid.64212.33) (ISNI:0000 0004 0463 2320) 
485  University Institute of Oncology-IUOPA, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Oviedo, Spain (GRID:grid.410712.1) 
486  Institut Bergonié, Bordeaux, France (GRID:grid.476460.7) (ISNI:0000 0004 0639 0505) 
487  Cancer Unit, MRC University of Cambridge, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
488  University of Southern California, USC Norris Comprehensive Cancer Center, Los Angeles, USA (GRID:grid.42505.36) (ISNI:0000 0001 2156 6853); Children’s Hospital Los Angeles, Department of Pathology and Laboratory Medicine, Center for Personalized Medicine, Los Angeles, USA (GRID:grid.239546.f) (ISNI:0000 0001 2153 6013) 
489  University of Sydney, Melanoma Institute Australia, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X); University of Sydney, Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X); John Curtin School of Medical Research, Canberra, Australia (GRID:grid.1001.0) (ISNI:0000 0001 2180 7477) 
490  PraxisClinic am Johannisplatz, MVZ Department of Oncology, Leipzig, Germany (GRID:grid.1001.0) 
491  Ghent University, Department of Information Technology, Ghent, Belgium (GRID:grid.5342.0) (ISNI:0000 0001 2069 7798); Ghent University, Department of Plant Biotechnology and Bioinformatics, Ghent, Belgium (GRID:grid.5342.0) (ISNI:0000 0001 2069 7798) 
492  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Fox Chase Cancer Center, Philadelphia, USA (GRID:grid.249335.a) (ISNI:0000 0001 2218 7820); Nationwide Children’s Hospital, Institute for Genomic Medicine, Columbus, USA (GRID:grid.240344.5) (ISNI:0000 0004 0392 3476) 
493  Oregon Health and Science University, Computational Biology Program, School of Medicine, Portland, USA (GRID:grid.5288.7) (ISNI:0000 0000 9758 5690) 
494  University of California Santa Cruz, Department of Biomolecular Engineering, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
495  Duke University, Department of Surgery, Durham, USA (GRID:grid.26009.3d) (ISNI:0000 0004 1936 7961) 
496  Barcelona Institute of Science and Technology (BIST), CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); Universitat Pompeu Fabra, Department of Experimental and Health Sciences, Institute of Evolutionary Biology (UPF-CSIC), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain (GRID:grid.425902.8) (ISNI:0000 0000 9601 989X); Universitat Autònoma de Barcelona, Institut Català de Paleontologia Miquel Crusafont, Barcelona, Spain (GRID:grid.7080.f) (ISNI:0000 0001 2296 0625) 
497  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); University of Glasgow, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X) 
498  Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain (GRID:grid.425902.8) (ISNI:0000 0000 9601 989X); Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (GRID:grid.10403.36) (ISNI:0000000091771775) 
499  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Massachusetts General Hospital, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924); Massachusetts General Hospital Center for Cancer Research, Charlestown, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
500  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Washington University School of Medicine, Division of Oncology, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
501  Royal Marsden NHS Foundation Trust, London and Sutton, UK (GRID:grid.5072.0) (ISNI:0000 0001 0304 893X); Imperial College, Department of Surgery and Cancer, London, UK (GRID:grid.7445.2) (ISNI:0000 0001 2113 8111) 
502  Oxford Nanopore Technologies, Applications Department, Oxford, UK (GRID:grid.437060.6) (ISNI:0000 0004 0567 5138) 
503  University of California San Francisco, Department of Obstetrics, Gynecology and Reproductive Services, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811) 
504  Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); Ontario Institute for Cancer Research, Genomics Research Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University California at Davis, Department of Biochemistry and Molecular Medicine, Sacramento, USA (GRID:grid.27860.3b) (ISNI:0000 0004 1936 9684) 
505  Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (GRID:grid.416166.2) (ISNI:0000 0004 0473 9881) 
506  Princess Margaret Cancer Centre, STTARR Innovation Facility, Toronto, Canada (GRID:grid.415224.4) (ISNI:0000 0001 2150 066X) 
507  University and Hospital Trust of Verona, Department of Surgery, Pancreas Institute, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X); Western Sydney University, Discipline of Surgery, Penrith, Australia (GRID:grid.1029.a) (ISNI:0000 0000 9939 5719) 
508  Yale University, Program in Computational Biology and Bioinformatics, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710); Yale University, Yale School of Medicine, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710) 
509  University of North Carolina at Chapel Hill, Department of Genetics, Lineberger Comprehensive Cancer Center, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
510  Henry Ford Hospital, Departments of Neurology and Neurosurgery, Detroit, USA (GRID:grid.413103.4) (ISNI:0000 0001 2160 8953) 
511  University of Queensland, St. Lucia, Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537); University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432) 
512  Oregon Health and Science University, Precision Oncology, OHSU Knight Cancer Institute, Portland, USA (GRID:grid.5288.7) (ISNI:0000 0000 9758 5690) 
513  University Medical Center Hamburg-Eppendorf, Institute of Pathology, Hamburg, Germany (GRID:grid.13648.38) (ISNI:0000 0001 2180 3484) 
514  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386); University of Cambridge, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
515  Kyushu University, Department of Health Sciences, Faculty of Medical Sciences, Fukuoka, Japan (GRID:grid.177174.3) (ISNI:0000 0001 2242 4849) 
516  Heidelberg Academy of Sciences and Humanities, Heidelberg, Germany (GRID:grid.461593.c) (ISNI:0000 0001 1939 6592) 
517  Vector Institute, Toronto, Canada (GRID:grid.494618.6); University of Toronto, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
518  University of Melbourne, Melbourne, Department of Clinical Pathology, VIC, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X); Roswell Park Cancer Institute, Department of Pathology, Buffalo, USA (GRID:grid.240614.5) (ISNI:0000 0001 2181 8635) 
519  University of Helsinki, Department of Computer Science, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071); University of Helsinki, Institute of Biotechnology, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071); University of Helsinki, Organismal and Evolutionary Biology Research Programme, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071) 
520  Washington University School of Medicine, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
521  Penrose St. Francis Health Services, Colorado Springs, USA (GRID:grid.430183.d) (ISNI:0000 0004 6354 3547) 
522  University of Bergen, Department of Clinical Science, Bergen, Norway (GRID:grid.7914.b) (ISNI:0000 0004 1936 7443) 
523  Ulm University and University Hospital of Ulm, Institute of Pathology, Ulm, Germany (GRID:grid.410712.1) (ISNI:0000 0004 0473 882X) 
524  National Cancer Center, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385) 
525  Genome Institute of Singapore, Singapore, Singapore (GRID:grid.418377.e) (ISNI:0000 0004 0620 715X) 
526  Barcelona Institute of Science and Technology (BIST), CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); Universitat Pompeu Fabra, Department of Experimental and Health Sciences, Institute of Evolutionary Biology (UPF-CSIC), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain (GRID:grid.425902.8) (ISNI:0000 0000 9601 989X) 
527  University of Cambridge, Li Ka Shing Centre, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386) 
528  German Cancer Aid, Bonn, Germany (GRID:grid.453370.6) (ISNI:0000 0001 2161 6363) 
529  Centre for Computational Biology, Duke-NUS Medical School, Programme in Cancer and Stem Cell Biology, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924) 
530  The Chinese University of Hong Kong, Shatin, NT, China (GRID:grid.10784.3a) (ISNI:0000 0004 1937 0482) 
531  Fourth Military Medical University, State Key Laboratory of Cancer Biology, and Xijing Hospital of Digestive Diseases, Shaanxi, China (GRID:grid.233520.5) (ISNI:0000 0004 1761 4404); Fourth Military Medical University, Shaanxi, China (GRID:grid.233520.5) (ISNI:0000 0004 1761 4404) 
532  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); University of Cambridge, Addenbrooke’s Hospital, Academic Department of Medical Genetics, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); MRC Cancer Unit, University of Cambridge, Cambridge, UK (GRID:grid.415041.5); The University of Cambridge School of Clinical Medicine, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934) 
533  St. Jude Children’s Research Hospital, Memphis, USA (GRID:grid.240871.8) (ISNI:0000 0001 0224 711X) 
534  Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University Health Network, Princess Margaret Cancer Centre, Toronto, Canada (GRID:grid.415224.4) (ISNI:0000 0001 2150 066X) 
535  Ontario Institute for Cancer Research, Genome Informatics Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
536  University of Chicago, Department of Medicine, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822) 
537  Department of Neurology, Mayo Clinic, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
538  Cambridge University Hospitals NHS Foundation Trust, Cambridge Oesophagogastric Centre, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386) 
539  Carleton College, Department of Computer Science, Northfield, USA (GRID:grid.253692.9) (ISNI:0000 0004 0445 5969) 
540  University of Melbourne, Melbourne, Department of Clinical Pathology, VIC, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X); University of Glasgow, Institute of Cancer Sciences, College of Medical Veterinary and Life Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X) 
541  University of Alabama at Birmingham, Department of Epidemiology, Birmingham, USA (GRID:grid.265892.2) (ISNI:0000000106344187); HudsonAlpha Institute for Biotechnology, Huntsville, USA (GRID:grid.417691.c) (ISNI:0000 0004 0408 3720); University of Alabama at Birmingham, O’Neal Comprehensive Cancer Center, Birmingham, USA (GRID:grid.265892.2) (ISNI:0000000106344187) 
542  Keio University School of Medicine, Department of Pathology, Tokyo, Japan (GRID:grid.26091.3c) (ISNI:0000 0004 1936 9959) 
543  National Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385) 
544  Sage Bionetworks, Seattle, USA (GRID:grid.430406.5) (ISNI:0000 0004 6023 5303) 
545  National Cancer Centre, Lymphoma Genomic Translational Research Laboratory, Singapore, Singapore (GRID:grid.410724.4) (ISNI:0000 0004 0620 9745) 
546  Robert-Bosch-Hospital, Department of Clinical Pathology, Stuttgart, Germany (GRID:grid.416008.b) (ISNI:0000 0004 0603 4965) 
547  Ontario Institute for Cancer Research, Genome Informatics Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Toronto, Department of Cell and Systems Biology, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
548  University of Melbourne, Melbourne, Department of Clinical Pathology, VIC, Australia (GRID:grid.1008.9) (ISNI:0000 0001 2179 088X) 
549  BGI-Shenzhen, Shenzhen, China (GRID:grid.21155.32) (ISNI:0000 0001 2034 1839); Karolinska Institutet, Department of Biosciences and Nutrition, Stockholm, Sweden (GRID:grid.4714.6) (ISNI:0000 0004 1937 0626) 
550  German Cancer Research Center (DKFZ), Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
551  National Cancer Center, Center for Liver Cancer, Research Institute and Hospital, Gyeonggi, South Korea (GRID:grid.410914.9) (ISNI:0000 0004 0628 9810) 
552  Sungkyunkwan University School of Medicine, Division of Hematology-Oncology, Samsung Medical Center, Seoul, South Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X); Sungkyunkwan University School of Medicine, Samsung Advanced Institute for Health Sciences and Technology, Seoul, South Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X) 
553  Sangmyung University, Cheonan Industry-Academic Collaboration Foundation, Cheonan, South Korea (GRID:grid.263136.3) (ISNI:0000 0004 0533 2389) 
554  Nottingham University Hospitals NHS Trust, Nottingham, UK (GRID:grid.240404.6) (ISNI:0000 0001 0440 1889) 
555  NYU Langone Medical Center, New York, USA (GRID:grid.240324.3) (ISNI:0000 0001 2109 4251) 
556  Memorial Sloan Kettering Cancer Center, Computational Biology Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
557  Aarhus University Hospital, Department of Molecular Medicine (MOMA), Aarhus N, Denmark (GRID:grid.154185.c) (ISNI:0000 0004 0512 597X); Aarhus University, Bioinformatics Research Centre (BiRC), Aarhus, Denmark (GRID:grid.7048.b) (ISNI:0000 0001 1956 2722) 
558  Cleveland Clinic, Department of Hematology and Medical Oncology, Cleveland, USA (GRID:grid.239578.2) (ISNI:0000 0001 0675 4725) 
559  University of North Carolina at Chapel Hill, Department of Pathology and Laboratory Medicine, School of Medicine, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208); University of North Carolina at Chapel Hill, Department of Genetics, Lineberger Comprehensive Cancer Center, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
560  Ontario Institute for Cancer Research, Genome Informatics Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of California San Francisco, Department of Radiation Oncology, San Francisco, USA (GRID:grid.266102.1) (ISNI:0000 0001 2297 6811) 
561  Department of Health Sciences Research, Mayo Clinic, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
562  Helen F. Graham Cancer Center at Christiana Care Health Systems, Newark, USA (GRID:grid.414316.5) (ISNI:0000 0004 0444 1241) 
563  Hopp Children’s Cancer Center (KiTZ), Heidelberg, Germany (GRID:grid.510964.f); Functional and Structural Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Heidelberg University Hospital, Heidelberg, Germany (GRID:grid.5253.1) (ISNI:0000 0001 0328 4908) 
564  CSRA Incorporated, Fairfax, USA (GRID:grid.414235.5) 
565  University College London Cancer Institute, Research Department of Pathology, London, UK (GRID:grid.83440.3b) (ISNI:0000000121901201) 
566  King’s Health Partners AHSC, King’s College London School of Medicine, Department of Research Oncology, Guy’s Hospital, London, UK (GRID:grid.13097.3c) (ISNI:0000 0001 2322 6764) 
567  Macquarie University, Faculty of Medicine and Health Sciences, Sydney, Australia (GRID:grid.1004.5) (ISNI:0000 0001 2158 5405) 
568  University Hospital of Minjoz, INSERM UMR 1098, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213) 
569  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Harvard Medical School, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Massachusetts General Hospital, Center for Cancer Research, Boston, USA (GRID:grid.32224.35) (ISNI:0000 0004 0386 9924) 
570  Spanish National Cancer Research Centre, Madrid, Spain (GRID:grid.7719.8) (ISNI:0000 0000 8700 1153) 
571  Fundeni Clinical Institute, Center of Digestive Diseases and Liver Transplantation, Bucharest, Romania (GRID:grid.415180.9) (ISNI:0000 0004 0540 9980) 
572  Cureline, Inc, South San Francisco, USA (GRID:grid.415180.9) 
573  Universitat Pompeu Fabra (UPF), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676) 
574  St. Luke’s Cancer Centre, Royal Surrey County Hospital NHS Foundation Trust, Guildford, UK (GRID:grid.412946.c) (ISNI:0000 0001 0372 6120) 
575  Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge Breast Unit, Addenbrooke’s Hospital, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386) 
576  University Institute of Oncology-IUOPA, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Oviedo, Spain (GRID:grid.24029.3d) 
577  University of Sydney, Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
578  East of Scotland Breast Service, Ninewells Hospital, Aberdeen, UK (GRID:grid.416266.1) (ISNI:0000 0000 9009 9462) 
579  Universitat Pompeu Fabra (UPF), Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); The Barcelona Institute of Science and Technology, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); University of Barcelona, IRSJD, IBUB, Department of Genetics, Microbiology and Statistics, Barcelona, Spain (GRID:grid.5841.8) (ISNI:0000 0004 1937 0247) 
580  Medical College of Wisconsin, Department of Obstetrics and Gynecology, Milwaukee, USA (GRID:grid.30760.32) (ISNI:0000 0001 2111 8460) 
581  Winship Cancer Institute of Emory University, Hematology and Medical Oncology, Atlanta, USA (GRID:grid.516089.3) (ISNI:0000 0004 9535 5639) 
582  Princeton University, Department of Computer Science, Princeton, USA (GRID:grid.16750.35) (ISNI:0000 0001 2097 5006) 
583  Vanderbilt University, Vanderbilt Ingram Cancer Center, Nashville, USA (GRID:grid.152326.1) (ISNI:0000 0001 2264 7217) 
584  University of Düsseldorf, Düsseldorf, Germany (GRID:grid.411327.2) (ISNI:0000 0001 2176 9917) 
585  Christian-Albrechts-University, Institute of Human Genetics, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986); Christian-Albrechts-University, Hematopathology Section, Institute of Pathology, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986) 
586  Ohio State University College of Medicine and Arthur G. James Comprehensive Cancer Center, Columbus, USA (GRID:grid.261331.4) (ISNI:0000 0001 2285 7943) 
587  Yokohama City University Graduate School of Medicine, Department of Surgery, Kanagawa, Japan (GRID:grid.268441.d) (ISNI:0000 0001 1033 6139) 
588  University of North Carolina at Chapel Hill, Research Computing Center, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
589  Erasmus Medical Center, Department of Medical Oncology, Josephine Nefkens Institute and Cancer Genomics Centre, Rotterdam, The Netherlands (GRID:grid.5645.2) (ISNI:000000040459992X); University of Copenhagen, Finsen Laboratory and Biotech Research and Innovation Centre (BRIC), Copenhagen, Denmark (GRID:grid.5254.6) (ISNI:0000 0001 0674 042X) 
590  University Health Network, Toronto General Hospital, Department of Pathology, Toronto, Canada (GRID:grid.417184.f) (ISNI:0000 0001 0661 1177); Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Toronto, Department of Medical Biophysics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); Toronto General Hospital, UHN Program in BioSpecimen Sciences, Toronto, Canada (GRID:grid.417184.f) (ISNI:0000 0001 0661 1177); University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); Memorial Sloan Kettering Cancer Center, Department of Pathology, Human Oncology and Pathogenesis Program, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
591  University Hospital Giessen, Pediatric Hematology and Oncology, Giessen, Germany (GRID:grid.411067.5) (ISNI:0000 0000 8584 9230) 
592  Oncologie Sénologie, ICM Institut Régional du Cancer, Montpellier, France (GRID:grid.418189.d) (ISNI:0000 0001 2175 1768) 
593  Norfolk and Norwich University Hospital NHS Trust, Norwich, UK (GRID:grid.240367.4) (ISNI:0000 0004 0445 7876) 
594  Christian-Albrechts-University, Institute of Clinical Molecular Biology, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986) 
595  University of Wuerzburg, Institute of Pathology, Wuerzburg, Germany (GRID:grid.8379.5) (ISNI:0000 0001 1958 8658) 
596  Royal Marsden NHS Foundation Trust, London and Sutton, UK (GRID:grid.5072.0) (ISNI:0000 0001 0304 893X); North Bristol NHS Trust, Department of Urology, Bristol, UK (GRID:grid.418484.5) (ISNI:0000 0004 0380 7221) 
597  Duke-NUS Medical School, Centre for Computational Biology, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924); Duke-NUS Medical School, Programme in Cancer and Stem Cell Biology, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924); National Heart Centre Singapore, SingHealth, Duke-NUS Institute of Precision Medicine, Singapore, Singapore (GRID:grid.419385.2) (ISNI:0000 0004 0620 9905) 
598  Vector Institute, Toronto, Canada (GRID:grid.494618.6); University of Toronto, Department of Computer Science, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
599  University of Bern, Department for Biomedical Research, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); University Hospital of Bern, University of Bern, Bern Center for Precision Medicine, Bern, Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157); Weill Cornell Medicine and New York Presbyterian Hospital, Englander Institute for Precision Medicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Meyer Cancer Center, Weill Cornell Medicine, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); Weill Cornell Medical College, Pathology and Laboratory, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X) 
600  The Barcelona Institute of Science and Technology, Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); Universitat Pompeu Fabra, Research Program on Biomedical Informatics, Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); Vall d’Hebron Institute of Oncology: VHIO, Barcelona, Spain (GRID:grid.411083.f) (ISNI:0000 0001 0675 8654) 
601  University and Hospital Trust of Verona, General and Hepatobiliary-Biliary Surgery, Pancreas Institute, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X) 
602  Memorial Sloan Kettering Cancer Center, Computational Biology Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); ETH Zurich, Department of Biology, Zürich, Switzerland (GRID:grid.5801.c) (ISNI:0000 0001 2156 2780); ETH Zurich, Department of Computer Science, Zurich, Switzerland (GRID:grid.5801.c) (ISNI:0000 0001 2156 2780); SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland (GRID:grid.419765.8) (ISNI:0000 0001 2223 3006); Weill Cornell Medical College, New York, USA (GRID:grid.5386.8) (ISNI:000000041936877X); University Hospital Zurich, Zurich, Switzerland (GRID:grid.412004.3) (ISNI:0000 0004 0478 9977) 
603  The Barcelona Institute of Science and Technology, Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); Universitat Pompeu Fabra, Research Program on Biomedical Informatics, Barcelona, Spain (GRID:grid.5612.0) (ISNI:0000 0001 2172 2676); Tata Institute of Fundamental Research, National Centre for Biological Sciences, Bangalore, India (GRID:grid.22401.35) (ISNI:0000 0004 0502 9283) 
604  Vancouver Prostate Centre, Vancouver, Canada (GRID:grid.412541.7) (ISNI:0000 0001 0684 7796); Simon Fraser University, Burnaby, Canada (GRID:grid.61971.38) (ISNI:0000 0004 1936 7494); Indiana University, Bloomington, USA (GRID:grid.411377.7) (ISNI:0000 0001 0790 959X) 
605  Department of Pathology, GZA-ZNA Hospitals, Antwerp, Belgium (GRID:grid.428965.4) (ISNI:0000 0004 7536 2436) 
606  Analytical Biological Services, Inc, Wilmington, USA (GRID:grid.422639.8) (ISNI:0000 0004 0372 3861) 
607  University and Hospital Trust of Verona, Department of Surgery, Pancreas Institute, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X); University of Sydney, Sydney Medical School, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
608  Memorial Sloan Kettering Cancer Center, Computational Biology Center, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); Harvard Medical School, cBio Center, Dana-Farber Cancer Institute, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Harvard Medical School, Department of Cell Biology, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
609  Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India (GRID:grid.410869.2) (ISNI:0000 0004 1766 7522) 
610  University of New South Wales (UNSW Sydney), Cancer Division, Garvan Institute of Medical Research, Kinghorn Cancer Centre, Sydney, Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432); The University of Newcastle, School of Environmental and Life Sciences, Faculty of Science, Ourimbah, Australia (GRID:grid.266842.c) (ISNI:0000 0000 8831 109X) 
611  German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); University Hospital of Essen, Department of Dermatology, Essen, Germany (GRID:grid.410718.b) (ISNI:0000 0001 0262 7331) 
612  Charité Universitätsmedizin Berlin, Department of Urology, Berlin, Germany (GRID:grid.6363.0) (ISNI:0000 0001 2218 4662); University Medical Center Hamburg-Eppendorf, Martini-Clinic, Prostate Cancer Center, Hamburg, Germany (GRID:grid.13648.38) (ISNI:0000 0001 2180 3484) 
613  University of Kiel, Department of General Internal Medicine, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986) 
614  European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Cambridge, UK (GRID:grid.225360.0) (ISNI:0000 0000 9709 7726); Max Delbrück Center for Molecular Medicine, Berlin Institute for Medical Systems Biology, Berlin, Germany (GRID:grid.419491.0) (ISNI:0000 0001 1014 0849); German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); German Cancer Consortium (DKTK), Partner site Berlin, Berlin, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
615  University of Sydney, Melanoma Institute Australia, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X); Royal Prince Alfred Hospital, Tissue Pathology and Diagnostic Oncology, Sydney, Australia (GRID:grid.413249.9) (ISNI:0000 0004 0385 0051); University of Sydney, Sydney Medical School, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
616  University of Pittsburgh, Pittsburgh, USA (GRID:grid.21925.3d) (ISNI:0000 0004 1936 9000) 
617  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Massachusetts Eye and Ear, Harvard Medical School, Department of Ophthalmology and Ocular Genomics Institute, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
618  NorthShore University HealthSystem, Center for Psychiatric Genetics, Evanston, USA (GRID:grid.240372.0) (ISNI:0000 0004 0400 4439) 
619  University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
620  Harvard Medical School, cBio Center, Dana-Farber Cancer Institute, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Harvard Medical School, Department of Cell Biology, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
621  Van Andel Research Institute, Grand Rapids, USA (GRID:grid.251017.0) (ISNI:0000 0004 0406 2057) 
622  University of Toronto, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
623  National Cancer Center Research Institute, National Cancer Center, Division of Cancer Genomics, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385); University of Tokyo, Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X) 
624  Japan Agency for Medical Research and Development, Tokyo, Japan (GRID:grid.480536.c) (ISNI:0000 0004 5373 4593) 
625  Korea University, Seoul, South Korea (GRID:grid.222754.4) (ISNI:0000 0001 0840 2678) 
626  Annai Systems, Inc, Carlsbad, USA (GRID:grid.26999.3d) 
627  Stanford University School of Medicine, Department of Genetics, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956) 
628  Walter Reed National Military Medical Center, Murtha Cancer Center, Bethesda, USA (GRID:grid.414467.4) (ISNI:0000 0001 0560 6544) 
629  Ulm University and Ulm University Medical Center, Institute of Human Genetics, Ulm, Germany (GRID:grid.410712.1) (ISNI:0000 0004 0473 882X); University of Kiel, Human Genetics, Kiel, Germany (GRID:grid.9764.c) (ISNI:0000 0001 2153 9986) 
630  Harvard Medical School, Department of Pathology, Brigham and Women’s Hospital, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Dana-Farber Cancer Institute, Harvard Medical School, Department of Oncologic Pathology, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X) 
631  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); University of Toronto, Department of Computer Science, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
632  University and Hospital Trust of Verona, Department of Surgery, Pancreas Institute, Verona, Italy (GRID:grid.411475.2) (ISNI:0000 0004 1756 948X); Memorial Sloan Kettering Cancer Center, Department of Surgery, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
633  Broad Institute of MIT and Harvard, Cambridge, USA (GRID:grid.66859.34) (ISNI:0000 0004 0546 1623); Stanford University School of Medicine, Department of Genetics, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956) 
634  University of North Carolina at Chapel Hill, Department of Genetics, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
635  Oregon Health and Science University, Portland, USA (GRID:grid.5288.7) (ISNI:0000 0000 9758 5690) 
636  The University of Texas MD Anderson Cancer Center, Center for RNA Interference and Noncoding RNA, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); The University of Texas MD Anderson Cancer Center, Department of Experimental Therapeutics, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); The University of Texas MD Anderson Cancer Center, Department of Gynecologic Oncology and Reproductive Medicine, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
637  University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK (GRID:grid.15628.38) (ISNI:0000 0004 0393 1193) 
638  Radboud University Nijmegen Medical Centre, Department of Radiation Oncology, Nijmegen, The Netherlands (GRID:grid.10417.33) (ISNI:0000 0004 0444 9382) 
639  University of Chicago, Institute for Genomics and Systems Biology, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822) 
640  Clinic for Hematology and Oncology, St.-Antonius-Hospital, Eschweiler, Germany (GRID:grid.459927.4) (ISNI:0000 0000 8785 9045) 
641  ETH Zurich, Department of Biology, Zürich, Switzerland (GRID:grid.5801.c) (ISNI:0000 0001 2156 2780); SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland (GRID:grid.419765.8) (ISNI:0000 0001 2223 3006); Korea University, Seoul, South Korea (GRID:grid.222754.4) (ISNI:0000 0001 0840 2678); Memorial Sloan Kettering Cancer Center, Computational and Systems Biology Program, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
642  University of Iceland, Reykjavik, Iceland (GRID:grid.14013.37) (ISNI:0000 0004 0640 0021) 
643  European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Cambridge, UK (GRID:grid.225360.0) (ISNI:0000 0000 9709 7726); European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany (GRID:grid.4709.a) (ISNI:0000 0004 0495 846X); German Cancer Research Center (DKFZ), Division of Computational Genomics and Systems Genetics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
644  Ninewells Hospital, Dundee Cancer Centre, Dundee, UK (GRID:grid.416266.1) (ISNI:0000 0000 9009 9462) 
645  University of Ulm and University Hospital of Ulm, Department for Internal Medicine III, Ulm, Germany (GRID:grid.410712.1) (ISNI:0000 0004 0473 882X) 
646  University of California Santa Cruz, Department of Biomolecular Engineering, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917); University of California Santa Cruz, UC Santa Cruz Genomics Institute, Santa Cruz, USA (GRID:grid.205975.c) (ISNI:0000 0001 0740 6917) 
647  China National GeneBank-Shenzhen, Shenzhen, China (GRID:grid.507779.b) (ISNI:0000 0004 4910 5858); Institut Curie, INSERM Unit 830, Paris, France (GRID:grid.418596.7) (ISNI:0000 0004 0639 6384) 
648  University of Tokyo, Genome Science Division, Research Center for Advanced Science and Technology, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X); Yokohama City University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Kanagawa, Japan (GRID:grid.268441.d) (ISNI:0000 0001 1033 6139) 
649  Radboud University Nijmegen Medical Centre, Department of Laboratory Medicine, Nijmegen, The Netherlands (GRID:grid.10417.33) (ISNI:0000 0004 0444 9382) 
650  German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany (GRID:grid.461742.2) (ISNI:0000 0000 8855 0365); German Cancer Research Center (DKFZ), Division of Cancer Genome Research, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
651  Singapore General Hospital, Department of General Surgery, Singapore, Singapore (GRID:grid.163555.1) (ISNI:0000 0000 9486 5048) 
652  Duke-NUS Medical School, Programme in Cancer and Stem Cell Biology, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924); Genome Institute of Singapore, Singapore, Singapore (GRID:grid.418377.e) (ISNI:0000 0004 0620 715X); National Heart Centre Singapore, SingHealth, Duke-NUS Institute of Precision Medicine, Singapore, Singapore (GRID:grid.419385.2) (ISNI:0000 0004 0620 9905); National University of Singapore, Cancer Science Institute of Singapore, Singapore, Singapore (GRID:grid.4280.e) (ISNI:0000 0001 2180 6431) 
653  University of Tokyo, Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, Tokyo, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X) 
654  Genome-Scale Biology Research Program, University of Helsinki, Department of Medical and Clinical Genetics, Helsinki, Finland (GRID:grid.7737.4) (ISNI:0000 0004 0410 2071) 
655  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); The Francis Crick Institute, London, UK (GRID:grid.451388.3) (ISNI:0000 0004 1795 1830) 
656  Cambridge University Hospitals NHS Foundation Trust, East Anglian Medical Genetics Service, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386) 
657  University of Cambridge, Li Ka Shing Centre, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); Columbia University, Irving Institute for Cancer Dynamics, New York, USA (GRID:grid.21729.3f) (ISNI:0000000419368729) 
658  Duke-NUS Medical School, Programme in Cancer and Stem Cell Biology, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924); National Heart Centre Singapore, SingHealth, Duke-NUS Institute of Precision Medicine, Singapore, Singapore (GRID:grid.419385.2) (ISNI:0000 0004 0620 9905); National University of Singapore, Cancer Science Institute of Singapore, Singapore, Singapore (GRID:grid.4280.e) (ISNI:0000 0001 2180 6431); Institute of Molecular and Cell Biology, Singapore, Singapore (GRID:grid.418812.6) (ISNI:0000 0004 0620 9243); National Cancer Centre Singapore, Laboratory of Cancer Epigenome, Division of Medical Science, Singapore, Singapore (GRID:grid.410724.4) (ISNI:0000 0004 0620 9745) 
659  Universidade de Santiago de Compostela, Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS), Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645); (CiMUS), Universidade de Santiago de Compostela, Department of Zoology, Genetics and Physical Anthropology, Santiago de Compostela, Spain (GRID:grid.11794.3a) (ISNI:0000000109410645) 
660  Universite Lyon, INCa-Synergie, Centre Léon Bérard, Lyon, France (GRID:grid.434706.2) 
661  Mayo Clinic, Department of Urology, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
662  Royal National Orthopaedic Hospital - Stanmore, Stanmore, UK (GRID:grid.416177.2) (ISNI:0000 0004 0417 7890) 
663  Universidade de Vigo, The Biomedical Research Centre (CINBIO), Vigo, Spain (GRID:grid.6312.6) (ISNI:0000 0001 2097 6738); University of Vigo, Department of Biochemistry, Genetics and Immunology, Vigo, Spain (GRID:grid.6312.6) (ISNI:0000 0001 2097 6738) 
664  Giovanni Paolo II / I.R.C.C.S. Cancer Institute, Bari, Italy (GRID:grid.6312.6) 
665  Institute of Pharmacy and Molecular Biotechnology and BioQuant, Heidelberg University, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
666  Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy, Rome, Italy (GRID:grid.414603.4); University of Verona, Verona, Italy (GRID:grid.5611.3) (ISNI:0000 0004 1763 1124) 
667  Centre National de Génotypage, CEA - Institute de Génomique, Evry, France (GRID:grid.418135.a) (ISNI:0000 0004 0641 3404) 
668  Maastricht University, CAPHRI Research School, Maastricht, The Netherlands (GRID:grid.5012.6) (ISNI:0000 0001 0481 6099) 
669  Centre Léon Bérard, Department of Biopathology, Lyon, France (GRID:grid.418116.b) (ISNI:0000 0001 0200 3174); Université Claude Bernard Lyon 1, Villeurbanne, France (GRID:grid.7849.2) (ISNI:0000 0001 2150 7757) 
670  Barcelona Institute of Science and Technology (BIST), CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299) 
671  Nottingham University Hospitals NHS Trust, Nottingham, UK (GRID:grid.240404.6) (ISNI:0000 0001 0440 1889); University Health Network, Princess Margaret Cancer Centre, Toronto, Canada (GRID:grid.415224.4) (ISNI:0000 0001 2150 066X) 
672  RIKEN Center for Integrative Medical Sciences, Laboratory for Medical Science Mathematics, Yokohama, Japan (GRID:grid.509459.4) (ISNI:0000 0004 0472 0267); Core Research for Evolutional Science and Technology (CREST), JST, Tokyo, Japan (GRID:grid.419082.6) (ISNI:0000 0004 1754 9200); University of Tokyo, Department of Biological Sciences, Laboratory for Medical Science Mathematics, Graduate School of Science, Yokohama, Japan (GRID:grid.26999.3d) (ISNI:0000 0001 2151 536X); Tokyo Medical and Dental University (TMDU), Department of Medical Science Mathematics, Medical Research Institute, Tokyo, Japan (GRID:grid.265073.5) (ISNI:0000 0001 1014 9130) 
673  University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK (GRID:grid.412563.7) (ISNI:0000 0004 0376 6589) 
674  Queen’s University, Centre for Cancer Research and Cell Biology, Belfast, UK (GRID:grid.4777.3) (ISNI:0000 0004 0374 7521) 
675  The University of Texas MD Anderson Cancer Center, Breast Medical Oncology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
676  Royal Stoke University Hospital, Stoke-on-Trent, UK (GRID:grid.439344.d) (ISNI:0000 0004 0641 6760); Johns Hopkins University School of Medicine, Department of Pathology, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311); Johns Hopkins University School of Medicine, Department of Surgery, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311) 
677  Uppsala University, Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala, Sweden (GRID:grid.8993.b) (ISNI:0000 0004 1936 9457); Karolinska Institute, Department of Oncology-Pathology, Science for Life Laboratory, Stockholm, Sweden (GRID:grid.4714.6) (ISNI:0000 0004 1937 0626) 
678  University of Southampton, School of Cancer Sciences, Faculty of Medicine, Southampton, UK (GRID:grid.5491.9) (ISNI:0000 0004 1936 9297) 
679  Tallinn University of Technology, Department of Gene Technology, Tallinn, Estonia (GRID:grid.6988.f) (ISNI:0000000110107715); SickKids Research Institute, The Hospital for Sick Children, Genetics and Genome Biology Program, Toronto, Canada (GRID:grid.42327.30) (ISNI:0000 0004 0473 9646) 
680  Winship Cancer Institute and School of Medicine, Emory University, Departments of Neurosurgery and Hematology and Medical Oncology, Atlanta, USA (GRID:grid.189967.8) (ISNI:0000 0001 0941 6502) 
681  University Health Network, Toronto General Hospital, Department of Pathology, Toronto, Canada (GRID:grid.417184.f) (ISNI:0000 0001 0661 1177) 
682  Barcelona Supercomputing Center (BSC), Barcelona, Spain (GRID:grid.10097.3f) (ISNI:0000 0004 0387 1602); Norwegian University of Science and Technology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Trondheim, Norway (GRID:grid.5947.f) (ISNI:0000 0001 1516 2393) 
683  University of Toronto, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); Argmix Consulting, North Vancouver, Canada (GRID:grid.17063.33) 
684  Ghent University, Department of Plant Biotechnology and Bioinformatics, Ghent, Belgium (GRID:grid.5342.0) (ISNI:0000 0001 2069 7798); Ghent University, Interuniversitair Micro-Electronica Centrum (IMEC), Department of Information Technology, Ghent, Belgium (GRID:grid.5342.0) (ISNI:0000 0001 2069 7798) 
685  University of Oxford, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948); University of Oxford, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948) 
686  University of Latvia, Institute of Mathematics and Computer Science, Riga, Latvia (GRID:grid.9845.0) (ISNI:0000 0001 0775 3222) 
687  University of Sydney, Discipline of Pathology, Sydney Medical School, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
688  Institut Curie, INSERM Unit 830, Paris, France (GRID:grid.418596.7) (ISNI:0000 0004 0639 6384) 
689  QIMR Berghofer Medical Research Institute, Department of Genetics and Computational Biology, Brisbane, Australia (GRID:grid.1049.c) (ISNI:0000 0001 2294 1395); University of Oxford, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948) 
690  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); Centre for Mathematical Sciences, University of Cambridge, Department of Applied Mathematics and Theoretical Physics, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); Memorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952); Columbia University, Department of Statistics, New York, USA (GRID:grid.21729.3f) (ISNI:0000000419368729) 
691  University of Queensland, St. Lucia, Institute for Molecular Bioscience, Brisbane, Australia (GRID:grid.1003.2) (ISNI:0000 0000 9320 7537) 
692  Uppsala University, Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala, Sweden (GRID:grid.8993.b) (ISNI:0000 0004 1936 9457) 
693  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Xi’an Jiaotong University, School of Computer Science and Technology, Xi’an, China (GRID:grid.43169.39) (ISNI:0000 0001 0599 1243); Xi’an Jiaotong University, School of Electronic and Information Engineering, Xi’an, China (GRID:grid.43169.39) (ISNI:0000 0001 0599 1243) 
694  The University of Texas MD Anderson Cancer Center, Department of Bioinformatics and Computational Biology, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); Baylor College of Medicine, Quantitative and Computational Biosciences Graduate Program, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X) 
695  Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386); Cambridge University Hospitals NHS Foundation Trust, Department of Histopathology, Cambridge, UK (GRID:grid.24029.3d) (ISNI:0000 0004 0383 8386) 
696  Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK (GRID:grid.10306.34) (ISNI:0000 0004 0606 5382); University of Oxford, Big Data Institute, Li Ka Shing Centre, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948); University of Oxford, Oxford NIHR Biomedical Research Centre, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948) 
697  Georgia Regents University Cancer Center, Augusta, USA (GRID:grid.410427.4) (ISNI:0000 0001 2284 9329) 
698  Wythenshawe Hospital, Manchester, UK (GRID:grid.417286.e) (ISNI:0000 0004 0422 2524) 
699  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Washington University School of Medicine, St. Louis, Department of Medicine and Department of Genetics, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Washington University School of Medicine, Department of Genetics, St.Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
700  German Cancer Research Center (DKFZ), Division of Theoretical Bioinformatics, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584); Leibniz Institute of Baltic Sea Research, Department of Biological Oceanography, Rostock, Germany (GRID:grid.423940.8) (ISNI:0000 0001 2188 0463) 
701  Barcelona Institute of Science and Technology (BIST), CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona, Spain (GRID:grid.473715.3) (ISNI:0000 0004 6475 7299); University of Oxford, Wellcome Centre for Human Genetics, Oxford, UK (GRID:grid.4991.5) (ISNI:0000 0004 1936 8948) 
702  Baylor College of Medicine, Human Genome Sequencing Center, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X); Baylor College of Medicine, Department of Molecular and Human Genetics, Houston, USA (GRID:grid.39382.33) (ISNI:0000 0001 2160 926X) 
703  Thoracic Oncology Laboratory, Mayo Clinic, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
704  Ontario Institute for Cancer Research, Computational Biology Program, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X); Ontario Institute for Cancer Research, PanCuRx Translational Research Initiative, Toronto, Canada (GRID:grid.419890.d) (ISNI:0000 0004 0626 690X) 
705  The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Institute for Genomic Medicine, Nationwide Children’s Hospital, Columbus, USA (GRID:grid.240344.5) (ISNI:0000 0004 0392 3476) 
706  Division of Gynecologic Oncology, Mayo Clinic, Department of Obstetrics and Gynecology, Rochester, USA (GRID:grid.66875.3a) (ISNI:0000 0004 0459 167X) 
707  Vector Institute, Toronto, Canada (GRID:grid.494618.6); University of Toronto, The Donnelly Centre, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938); University of Toronto, Department of Computer Science, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
708  International Institute for Molecular Oncology, Poznań, Poland (GRID:grid.510975.f) (ISNI:0000 0004 6004 7353); Poznan University of Medical Sciences, Poznań, Poland (GRID:grid.22254.33) (ISNI:0000 0001 2205 0971) 
709  German Cancer Research Center (DKFZ), Genomics and Proteomics Core Facility High Throughput Sequencing Unit, Heidelberg, Germany (GRID:grid.7497.d) (ISNI:0000 0004 0492 0584) 
710  National Cancer Centre Singapore, NCCS-VARI Translational Research Laboratory, Singapore, Singapore (GRID:grid.410724.4) (ISNI:0000 0004 0620 9745) 
711  Canada’s Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada (GRID:grid.434706.2) (ISNI:0000 0004 0410 5424); The McDonnell Genome Institute at Washington University, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
712  Washington University, Edison Family Center for Genome Sciences and Systems Biology, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002) 
713  University of Toronto, Department of Medical Biophysics, Toronto, Canada (GRID:grid.17063.33) (ISNI:0000 0001 2157 2938) 
714  University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X); MRC-University of Glasgow Centre for Virus Research, Glasgow, UK (GRID:grid.301713.7) (ISNI:0000 0004 0393 3981) 
715  Annai Systems, Inc, Carlsbad, USA (GRID:grid.32224.35) 
716  Oregon Health and Science University, Department of Medical Informatics and Clinical Epidemiology, Division of Bioinformatics and Computational Biology, OHSU Knight Cancer Institute, Portland, USA (GRID:grid.5288.7) (ISNI:0000 0000 9758 5690) 
717  Huazhong University of Science and Technology, School of Electronic Information and Communications, Wuhan, China (GRID:grid.33199.31) (ISNI:0000 0004 0368 7223) 
718  Xi’an Jiaotong University, School of Computer Science and Technology, Xi’an, China (GRID:grid.43169.39) (ISNI:0000 0001 0599 1243) 
719  Peking University Cancer Hospital and Institute, Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing, China (GRID:grid.412474.0) (ISNI:0000 0001 0027 0586) 
720  Johns Hopkins University, Department of Applied Mathematics and Statistics, Baltimore, USA (GRID:grid.21107.35) (ISNI:0000 0001 2171 9311) 
721  National Cancer Center Research Institute, National Cancer Center, Division of Cancer Genomics, Tokyo, Japan (GRID:grid.272242.3) (ISNI:0000 0001 2168 5385); Osaka University, Department of Cancer Genome Informatics, Graduate School of Medicine, Osaka, Japan (GRID:grid.136593.b) (ISNI:0000 0004 0373 3971) 
722  European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany (GRID:grid.4709.a) (ISNI:0000 0004 0495 846X); Heidelberg University, Institute of Computer Science, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373) 
723  University of Sydney, School of Mathematics and Statistics, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
724  Xi’an Jiaotong University, School of Electronic and Information Engineering, Xi’an, China (GRID:grid.43169.39) (ISNI:0000 0001 0599 1243); Xi’an Jiaotong University, The First Affiliated Hospital, Xi’an, China (GRID:grid.43169.39) (ISNI:0000 0001 0599 1243) 
725  Washington University School of Medicine, St. Louis, Department of Medicine and Department of Genetics, St. Louis, USA (GRID:grid.4367.6) (ISNI:0000 0001 2355 7002); Memorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, USA (GRID:grid.51462.34) (ISNI:0000 0001 2171 9952) 
726  The Chinese University of Hong Kong, Department of Medicine and Therapeutics, Shatin, NT, China (GRID:grid.10784.3a) (ISNI:0000 0004 1937 0482) 
727  The University of Texas MD Anderson Cancer Center, Department of Biostatistics, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776) 
728  Duke-NUS Medical School, Singapore, Singapore (GRID:grid.428397.3) (ISNI:0000 0004 0385 0924) 
729  Shanghai Jiaotong University School of Medicine, Department of Surgery, Ruijin Hospital, Shanghai, China (GRID:grid.16821.3c) (ISNI:0000 0004 0368 8293) 
730  University of Cambridge, Li Ka Shing Centre, Cancer Research UK Cambridge Institute, Cambridge, UK (GRID:grid.5335.0) (ISNI:0000000121885934); University of Glasgow, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X); University of Glasgow, School of Computing Science, Glasgow, UK (GRID:grid.8756.c) (ISNI:0000 0001 2193 314X) 
731  Oslo University Hospital, Division of Orthopaedic Surgery, Oslo, Norway (GRID:grid.55325.34) (ISNI:0000 0004 0389 8485) 
732  National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany (GRID:grid.461742.2) (ISNI:0000 0000 8855 0365) 
733  Monash University, Eastern Clinical School, Melbourne, Australia (GRID:grid.1002.3) (ISNI:0000 0004 1936 7857); Epworth HealthCare, Richmond, Australia (GRID:grid.414539.e) (ISNI:0000 0001 0459 5396) 
734  Peking University, Beijing, China (GRID:grid.11135.37) (ISNI:0000 0001 2256 9319) 
735  Second Military Medical University, Shanghai, China (GRID:grid.73113.37) (ISNI:0000 0004 0369 1660) 
736  The University of Texas Health Science Center at Houston, Houston, USA (GRID:grid.267308.8) (ISNI:0000 0000 9206 2401); Xi’an Jiaotong University, School of Computer Science and Technology, Xi’an, China (GRID:grid.43169.39) (ISNI:0000 0001 0599 1243) 
737  Yale University, Program in Computational Biology and Bioinformatics, New Haven, USA (GRID:grid.47100.32) (ISNI:0000000419368710); The Ohio State University, Department of Biomedical Informatics, College of Medicine, Columbus, USA (GRID:grid.261331.4) (ISNI:0000 0001 2285 7943); The Ohio State University Comprehensive Cancer Center (OSUCCC – James), Columbus, USA (GRID:grid.413944.f) (ISNI:0000 0001 0447 4797) 
738  The University of Texas School of Biomedical Informatics (SBMI) at Houston, Houston, USA (GRID:grid.267308.8) (ISNI:0000 0000 9206 2401) 
739  The University of Texas MD Anderson Cancer Center, Department of Biostatistics, Houston, USA (GRID:grid.240145.6) (ISNI:0000 0001 2291 4776); University of North Carolina at Chapel Hill, Department of Biostatistics, Chapel Hill, USA (GRID:grid.10698.36) (ISNI:0000000122483208) 
740  Feinberg School of Medicine, Northwestern University, Department of Biochemistry and Molecular Genetics, Chicago, USA (GRID:grid.16753.36) (ISNI:0000 0001 2299 3507) 
741  University of Sydney, Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X); Westmead Hospital, Department of Gynaecological Oncology, Sydney, Australia (GRID:grid.413252.3) (ISNI:0000 0001 0180 6477); University of Sydney, Faculty of Medicine and Health, Sydney, Australia (GRID:grid.1013.3) (ISNI:0000 0004 1936 834X) 
742  Erasmus Medical Center Rotterdam, Department of Pathology, Rotterdam, The Netherlands (GRID:grid.5645.2) (ISNI:000000040459992X) 
743  The Netherlands Cancer Institute, Division of Molecular Carcinogenesis, Amsterdam, The Netherlands (GRID:grid.430814.a) (ISNI:0000 0001 0674 1393) 
744  University of Zurich, Institute of Molecular Life Sciences, Zurich, Switzerland (GRID:grid.7400.3) (ISNI:0000 0004 1937 0650); University of Zurich, Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, Zurich, Switzerland (GRID:grid.7400.3) (ISNI:0000 0004 1937 0650) 
Publication year
2020
Publication date
2020
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2748042952
Copyright
© The Author(s) 2020. corrected publication 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.