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Abstract
Cardiac sarcoidosis (CS) is a chameleon of cardiology, and it can mimic different cardiac diseases; among them is arrhythmogenic cardiomyopathy (ACM). We admitted a 70‐year‐old female patient with heart failure symptoms in 2015, who fulfilled all major ECG and non‐invasive imaging criteria of biventricular ACM. She was well with the recommended medications for 3 years, showing only isolated cardiac involvement, but in 2018, cervical and mediastinal lymphadenopathy appeared and cervical lymph node core biopsy histology, bronchoalveolar lavage flow cytometry strongly suggested extracardiac sarcoidosis. Therefore, our suspicion was that sarcoidosis is responsible for the cardiac involvement, which was not confirmed by PET‐CT and gallium scintigraphy examinations. At the end of 2018, she died in septicaemia with multiorgan failure, and only autopsy verified her CS. A new ECG algorithm published in 2021 for the differential diagnosis of CS and biventricular ACM, when applied on her ECGs recorded in 2015, suggested the diagnosis of CS.
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Details
1 Department of Medicine and Hematology, Semmelweis University, Budapest, Hungary
2 Heart and Vascular Center, Semmelweis University, Budapest, Hungary
3 Department of Pulmonology, Semmelweis University, Budapest, Hungary
4 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
5 Department of Medicine, Division of Non‐Invasive Cardiology, University of Szeged, Szeged, Hungary
6 Department of Histopathology, Sheffield Teaching Hospitals, NHS Foundation Trust, Northern General Hospital, Sheffield, UK