Abstract

Background

Although risk factors of occlusive acute mesenteric ischemia are well known, triggering factors of nonocclusive mesenteric ischemia (NOMI) remain unclear. Alongside to the known risk factors for NOMI, the role of atherosclerosis is not fully elucidated. The purpose of our study was to evaluate whether abdominal atherosclerosis is a risk factor for NOMI.

Methods

From January 2018 to December 2021, all consecutive patients admitted to the intensive care unit who underwent contrast-enhanced CT for suspicion of NOMI were evaluated for inclusion. Clinical and biological data at the time of the CT scan were retrospectively extracted from medical charts and reviewed by a single radiologist. The cohorts were matched by a 1:1 propensity score based on the patient clinical, biological data, and abdominal CT features associated with NOMI. Noncontrast CT acquisitions were used to calculate calcium scores of the abdominal aorta, celiac trunk, superior mesenteric artery (SMA), and common iliac artery according to the Agatston method. Analyses were performed before and after propensity score matching.

Results

Among the 165 critically ill patients included, 59 (36%) had NOMI. Before matching analysis, the SMA and total abdominal Agatston calcium scores were not different between patients without and with NOMI (52.00 [IQR = 0, 473] vs. 137.00 [IQR = 0, 259], P = 0.857, respectively, and 7253 [IQR = 1220, 21738] versus 5802 [IQR = 2075, 15,084]; P = 0.723). The results were similar after matching 38 patients with NOMI and 38 without: 153 [IQR = 0, 665] versus 85 [IQR = 0, 240] (P = 0.312) for the SMA calcium score, and 7915 [IQR = 1812, 21561] versus 4139 [IQR = 1440, 9858] (P = 0.170) for the total abdominal Agatston calcium score.

Conclusion

Our results suggest that atherosclerosis is not a risk factor for NOMI in critically ill patients.

Details

Title
Abdominal atherosclerosis is not a risk factor of nonocclusive mesenteric ischemia among critically ill patients: a propensity matching study
Author
Konan, Anhum 1 ; Piton, Gael 2 ; Ronot, Maxime 3 ; Hassoun, Youness 4 ; Winiszewski, Hadrien 2 ; Besch, Guillaume 5 ; Doussot, Alexandre 6 ; Delabrousse, Eric 7 ; Calame, Paul 8   VIAFID ORCID Logo 

1  University of Bourgogne Franche-Comté, CHRU Besançon, Department of Radiology, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213); Yopougon University Hospital, Department of Radiology, Abidjan, Côte d’Ivoire (GRID:grid.411158.8) 
2  University of Bourgogne Franche-Comté, CHRU Besançon, Medical Intensive Care Unit, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213) 
3  University Hospitals Paris Nord Val-de-Seine, AP—HP, Beaujon, Department of Radiology, Clichy, France (GRID:grid.50550.35) (ISNI:0000 0001 2175 4109) 
4  University of Bourgogne Franche-Comté, CHRU Besançon, Department of Radiology, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213) 
5  University of Bourgogne Franche-Comté, CHRU Besançon, Surgical Intensive Care Unit, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213) 
6  University of Bourgogne Franche-Comté, CHRU Besançon, Department of Digestive Surgery, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213) 
7  University of Bourgogne Franche-Comté, CHRU Besançon, Department of Radiology, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213); University of Franche-Comté, EA 4662 Nanomedicine Lab, Imagery and Therapeutics, Besançon, France (GRID:grid.7459.f) (ISNI:0000 0001 2188 3779) 
8  University of Bourgogne Franche-Comté, CHRU Besançon, Department of Radiology, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213); University of Franche-Comté, EA 4662 Nanomedicine Lab, Imagery and Therapeutics, Besançon, France (GRID:grid.7459.f) (ISNI:0000 0001 2188 3779); Hôpital Jean Minjoz, Service de Radiologie, CHRU Besançon, Besançon, France (GRID:grid.411158.8) (ISNI:0000 0004 0638 9213) 
Pages
117
Publication year
2022
Publication date
Dec 2022
Publisher
Springer Nature B.V.
e-ISSN
21105820
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s13613-022-01096-4
ProQuest document ID
2757874966
Copyright
© The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.