Abstract
Background
Management of the open abdomen is an increasingly common part of surgical practice. The purpose of this review is to examine the scientific background for the use of temporary abdominal closure (TAC) in the open abdomen as a way to modulate the local and systemic inflammatory response, with an emphasis on decompression after abdominal compartment syndrome (ACS).
Methods
A review of the relevant English language literature was conducted. Priority was placed on articles published within the last 5 years.
Results/Conclusion
Recent data from our group and others have begun to lay the foundation for the concept of TAC as a method to modulate the local and/or systemic inflammatory response in patients with an open abdomen resulting from ACS.
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1 University of Texas Medical School at Houston, Department of Pediatric Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401); University of Texas Medical School at Houston, Department of Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401); Texas A & M University, Michael E. DeBakey Institute for Comparative Cardiovascular Science and Biomedical Devices, USA (GRID:grid.264756.4) (ISNI:0000000446872082)
2 University of Texas Medical School at Houston, Department of Pediatric Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401)
3 University of Texas Medical School at Houston, Department of Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401)
4 University of Texas Medical School at Houston, Department of Pediatric Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401); University of Texas Medical School at Houston, Department of Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401)
5 University of Texas Medical School at Houston, Department of Pediatric Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401); Texas A & M University, Michael E. DeBakey Institute for Comparative Cardiovascular Science and Biomedical Devices, USA (GRID:grid.264756.4) (ISNI:0000000446872082)
6 Texas A & M University, Michael E. DeBakey Institute for Comparative Cardiovascular Science and Biomedical Devices, USA (GRID:grid.264756.4) (ISNI:0000000446872082)
7 University of Texas Medical School at Houston, Department of Pediatric Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401); Texas A & M University, Michael E. DeBakey Institute for Comparative Cardiovascular Science and Biomedical Devices, USA (GRID:grid.264756.4) (ISNI:0000000446872082); University of Texas Medical School at Houston, Department of Pediatric Surgery, Houston, USA (GRID:grid.267308.8) (ISNI:0000000092062401)