Abstract

Background

Alzheimer’s disease and related dementias (AD/ADRD) are a public health challenge for Vietnam because of its rapidly aging population. However, very few community-based programs exist to support people living with AD/ADRD and their family caregivers. Resources for Enhancing Alzheimer’s Caregiver Health in Vietnam (REACH VN) is a culturally adapted family caregiver intervention shown in a pilot study to be feasible and promising in terms of preliminary efficacy. We describe the protocol for a larger cluster randomized controlled trial (RCT) to test the efficacy of REACH VN among family caregivers of people living with dementia in a semi-rural area outside of Hanoi, Vietnam.

Methods

Thirty-two clusters with approximately 350 caregivers will be randomized to either REACH VN intervention or enhanced usual care. REACH VN is a multicomponent intervention delivered in-home or by phone over the course of 2 to 3 months. To be eligible, family caregivers need to be ≥18 years old, be the person who provides the most day-to-day care for people living with dementia, and have a score ≥ 6 on the Zarit Burden Interview-4. The primary outcomes are caregiver burden (Zarit Burden Interview-12) and psychological distress (Patient Health Questionnaire-4). Secondary outcomes include caregiver somatic symptoms (Patient Health Questionnaire-15) and perceived stress (Perceived Stress Scale-10). These outcomes will be assessed at baseline, 3 months, and 6 months. Exploratory analyses to examine potential mediators of primary outcomes are also planned.

Discussion

To our knowledge, this is the first large-scale study to test the efficacy of a community-based family dementia caregiver intervention in Vietnam. Results from this study will help inform efforts to widely deliver the REACH VN intervention or similar community-based family dementia caregiver support programs in Vietnam and other low- and middle-income countries (LMIC).

Trial registration

ClinicalTrials.govNCT04542317. Registered on 9 September 2020

Details

Title
Resources for Enhancing Alzheimer’s Caregiver Health in Vietnam (REACH VN): study protocol for a cluster randomized controlled trial to test the efficacy of a family dementia caregiver intervention in Vietnam
Author
Tran, Duyen 1 ; Nguyen, Huong 2 ; Pham, Thang 3 ; Nguyen, Anh T. 4 ; Nguyen, Hung T. 4 ; Nguyen, Ngoc B. 5 ; Nguyen, Bien H. 6 ; Harvey, Danielle 7 ; Gitlin, Laura 8 ; Hinton, Ladson 9   VIAFID ORCID Logo 

1  University of California, Davis, Department of Neurology, Sacramento, USA (GRID:grid.27860.3b) (ISNI:0000 0004 1936 9684) 
2  University of Minnesota, School of Nursing, Minneapolis, USA (GRID:grid.17635.36) (ISNI:0000000419368657) 
3  National Geriatric Hospital, Hanoi, Vietnam (GRID:grid.17635.36); Hanoi Medical University, Hanoi, Vietnam (GRID:grid.56046.31) (ISNI:0000 0004 0642 8489) 
4  National Geriatric Hospital, Hanoi, Vietnam (GRID:grid.56046.31); Hanoi Medical University, Hanoi, Vietnam (GRID:grid.56046.31) (ISNI:0000 0004 0642 8489) 
5  National Geriatric Hospital, Hanoi, Vietnam (GRID:grid.56046.31) 
6  Hai Duong Provincial General Hospital, Hai Duong, Vietnam (GRID:grid.56046.31) 
7  University of California, Davis, Department of Public Health Sciences, Davis, USA (GRID:grid.27860.3b) (ISNI:0000 0004 1936 9684) 
8  Drexel University, College of Nursing and Health Professions, Philadelphia, USA (GRID:grid.166341.7) (ISNI:0000 0001 2181 3113) 
9  University of California, Davis, Department of Psychiatry and Behavioral Sciences, Sacramento, USA (GRID:grid.27860.3b) (ISNI:0000 0004 1936 9684) 
Pages
377
Publication year
2022
Publication date
Dec 2022
Publisher
Springer Nature B.V.
e-ISSN
17456215
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s13063-022-06228-6
ProQuest document ID
2808575215
Copyright
© The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.