Abstract
Background
Increased uptake of sodium is a major cause for cardiovascular disease and mortality. Reduction of daily salt intake below a reference level of 2 g per day (the equivalent to 5 g salt/day) is known to effectively reduce cardiovascular mortality. The widespread use of social media, with a constant increase in video consumption, is opening new avenues for the dissemination of innovative and scalable approaches to health-related information and recommendations for a healthy diet, such as via video interventions with short animated stories (SAS).
Objective
This study will evaluate the effect of a sodium intake-SAS video intervention on immediate and medium-term knowledge about dietary sodium. Beyond that, immediate and medium-term effects on behavioral expectation to reduce sodium intake as well as voluntary post-trial engagement with the video content will be examined.
Methods
In this 4-armed, parallel, randomized controlled trial, 10,000 adult, US participants will be randomly assigned to (1) a short, animated storytelling intervention video on sodium as a cardiovascular disease risk factor followed by surveys assessing the facts on sodium and cardiovascular disease conveyed in the video (2) the surveys only, (3) an attention placebo control video followed by the before mentioned surveys, and (4) an arm that is exposed to neither the video nor the surveys. Two weeks later, participants in all four arms will complete all of the surveys.
Results
Primary outcomes are the immediate and medium-term effects of the short, animated storytelling intervention video on knowledge about dietary sodium. Secondary outcomes are immediate and medium-term effects of the short, animated storytelling intervention on behavioral expectation to reduce sodium intake as well as voluntary post-trial engagement with the video content.
Conclusion
This study will extend the knowledge on the effects of short, animated storytelling for the containment of the global cardiovascular disease burden. Knowledge on the groups that may be more likely to voluntarily engage with SAS video content will help to improve targeting of future interventions towards audiences at risk.
Trial registration {2a}
ClinicalTrials.gov NCT05735457. Registered on February 21, 2023.
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Details
; Nguyen, K 2 ; Aziz, M Abd El 3 ; Überreiter, C 4 ; Bärnighausen, T 5 ; Adam, M 6 1 University of Freiburg, Interdisciplinary Medical Intensive Care, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany (GRID:grid.5963.9); Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373)
2 Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373)
3 Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); Heidelberg University Hospital, Division of Infectious Diseases and Tropical Medicine, Heidelberg, Germany (GRID:grid.5253.1) (ISNI:0000 0001 0328 4908)
4 University of Freiburg, Interdisciplinary Medical Intensive Care, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany (GRID:grid.5963.9)
5 Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); Harvard T. H Chan School of Public Health, Department of Global Health and Population, Boston, USA (GRID:grid.38142.3c) (ISNI:000000041936754X); Africa Health Research Institute (AHRI), Somkhele, South Africa (GRID:grid.488675.0) (ISNI:0000 0004 8337 9561)
6 Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany (GRID:grid.7700.0) (ISNI:0000 0001 2190 4373); Stanford University School of Medicine, Department of Pediatrics, Stanford, USA (GRID:grid.168010.e) (ISNI:0000000419368956)




