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© 2023. This work is published under http://dentistry.tbzmed.ac.ir/jpid/index.php/jpid/about/editorialPolicies#openAccessPolicy (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

ZnO nanoparticles could be toxic against HGF in high concentrations and with prolonged exposure. [...]incorporating ZnO nanoparticles into a biocompatible polymer such as PLGA could be a beneficial strategy for reducing their toxicity. Because of their nanometric scale, nanoparticles can easily infiltrate the cell wall. [...]given their high intrinsic toxicity, ensuring the safety of these nanoparticles against HGF cells is essential. [...]incorporating ZnO nanoparticles into a biocompatible polymer such as PLGA might be a beneficial strategy for reducing the toxicity of these metallic nanoparticles. [...]the decanted PLGA-ZnO dispersion was allowed to dry at room temperature overnight.18 FESEM analysis The samples were treated in an ultrasonic bath for 15 minutes.

Details

Title
Cytotoxicity of PLGA-zinc oxide nanocomposite on human gingival fibroblasts
Author
Mozaffari, Asieh 1 ; Mirzapour, Samira Mohammad 2 ; Rad, Motahare Sharifi 3 ; Ranjbaran, Mehdi 4 

 Department of Periodontics, Faculty of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran 
 Department of Periodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran 
 Department of Pharmaceutical Nanotechnology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran 
 Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran 
Pages
28-34
Section
Research Article
Publication year
2023
Publication date
2023
Publisher
Tabriz University of Medical Sciences
ISSN
20087748
e-ISSN
20087756
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2859257856
Copyright
© 2023. This work is published under http://dentistry.tbzmed.ac.ir/jpid/index.php/jpid/about/editorialPolicies#openAccessPolicy (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.