Abstract

Diffuse large B cell lymphoma (DLBCL) is the most common type of lymphoma in adults with high heterogeneity. Recent studies have manifested that the occurrence and development of DLBCL is related to hepatitis B virus (HBV) infection. As a medium-to-high prevalence area of HBV infection in China, the importance and exact mechanism of HBV infection in the occurrence of DLBCL have attracted considerable attention. HBV-associated DLBCL has unique clinical characteristics, poor treatment effect and inferior prognosis. HBV reactivation caused by DLBCL treatment also needs for constant vigilance. In this review we summarize the current research progress in the epidemiology, pathogenesis, clinical characteristics, HBV reactivation and antiviral therapies of HBV-associated DLBCL, in order to provide reference for clinical diagnosis and treatment.

Details

Title
Hepatitis B virus–associated diffuse large B cell lymphoma: epidemiology, biology, clinical features and HBV reactivation
Author
Jiayu, Zhu 1 ; Zhang, Qingyuan 1   VIAFID ORCID Logo 

1  Harbin Medical University Cancer Hospital, Department of Medical Oncology, Harbin, China (GRID:grid.412651.5) (ISNI:0000 0004 1808 3502) 
Pages
38
Publication year
2023
Publication date
Dec 2023
Publisher
Springer Nature B.V.
e-ISSN
27314529
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1007/s44178-023-00061-w
ProQuest document ID
2879467357
Copyright
© The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.