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Rx
For 100 mL
Acyclovir sodium 4 g
Ora Plus 50 mL
Ora Sweet or Ora Sweet SF qs 100 mL
METHOD OF PREPARATION
1. Calculate the required quantity of each ingrethent for the total amount to be prepared.
2. Weigh and/or measure each ingrethent accurately.
3. Reconstitute the acyclovir sodium vial with the smallest quantity of purified water required to allow withdrawal from the vial. Note: It does not have to all he in solution.
4. Place in a suitable calibrated container.
5. Add the Ora-Plus geometrically anil mix well.
6. Add sufficient Ora-Svveet or Ora-Sweet SF to volume and mix well.
7. Package and label.
PACKAGING
Package in tight, light-resistant containers.1
LABELING
Keep out of reach of children. Use only as directed. Shake Well.
STABILITY
A beyond-use date of 12 hours can be used for this preparation.1
USE
Acyclovir oral suspension is used in the treatment of genital herpes, herpes zoster, and varicella in immunocompetent individuais.2
QUALITY CONTROL
Quality-control assessment can include weight/volume, pH, specific gravity, active drug assay, color, rheological properties/pourability, physical observation, and physical stability (discoloration, foreign materials, gas formation, mold growth).3
DISCUSSION
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