Details
Title
The tumor-enriched small molecule gambogic amide suppresses glioma by targeting WDR1-dependent cytoskeleton remodeling
Author
Qu, Jiaorong 1 ; Qiu, Bojun 1 ; Zhang, Yuxin 1 ; Hu, Yan 1 ; Wang, Zhixing 1 ; Guan, Zhiang 1 ; Qin, Yiming 1 ; Sui, Tongtong 1 ; Wu, Fan 2 ; Li, Boyang 1 ; Han, Wei 1 ; Peng, Xiaozhong 3
1 Peking Union Medical College, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Beijing, China (GRID:grid.506261.6) (ISNI:0000 0001 0706 7839); State Key Laboratory of Common Mechanism Research for Major Diseases, Beijing, China (GRID:grid.506261.6)
2 Capital Medical University, Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China (GRID:grid.24696.3f) (ISNI:0000 0004 0369 153X); Capital Medical University, Department of Neurosurgery, Beijing Tiantan Hospital, Beijing, China (GRID:grid.24696.3f) (ISNI:0000 0004 0369 153X)
3 Peking Union Medical College, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Beijing, China (GRID:grid.506261.6) (ISNI:0000 0001 0706 7839); State Key Laboratory of Respiratory Health and Multimorbidity, Beijing, China (GRID:grid.506261.6); Chinese Academy of Medical Sciences & Peking Union Medical College, National Human Diseases Animal Model Resource Center, Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Institute of Laboratory Animal Science, Beijing, China (GRID:grid.506261.6) (ISNI:0000 0001 0706 7839)
1 Peking Union Medical College, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Beijing, China (GRID:grid.506261.6) (ISNI:0000 0001 0706 7839); State Key Laboratory of Common Mechanism Research for Major Diseases, Beijing, China (GRID:grid.506261.6)
2 Capital Medical University, Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Beijing, China (GRID:grid.24696.3f) (ISNI:0000 0004 0369 153X); Capital Medical University, Department of Neurosurgery, Beijing Tiantan Hospital, Beijing, China (GRID:grid.24696.3f) (ISNI:0000 0004 0369 153X)
3 Peking Union Medical College, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Beijing, China (GRID:grid.506261.6) (ISNI:0000 0001 0706 7839); State Key Laboratory of Respiratory Health and Multimorbidity, Beijing, China (GRID:grid.506261.6); Chinese Academy of Medical Sciences & Peking Union Medical College, National Human Diseases Animal Model Resource Center, Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Institute of Laboratory Animal Science, Beijing, China (GRID:grid.506261.6) (ISNI:0000 0001 0706 7839)
Pages
424
Publication year
2023
Publication date
2023
ISSN
20959907
e-ISSN
20593635
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2886746232
Copyright
© The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.